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Protein

Probable acyl-CoA dehydrogenase FadE10

Gene

fadE10

Organism
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor.

Cofactori

FADBy similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei422 – 4221Proton acceptorBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

FAD, Flavoprotein

Names & Taxonomyi

Protein namesi
Recommended name:
Probable acyl-CoA dehydrogenase FadE10 (EC:1.3.-.-)
Gene namesi
Name:fadE10
Ordered Locus Names:Mb0897
OrganismiMycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Taxonomic identifieri233413 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001419 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 650650Probable acyl-CoA dehydrogenase FadE10PRO_0000201210Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP63430.
SMRiP63430. Positions 25-587.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi443 – 46422Ala-richAdd
BLAST

Sequence similaritiesi

Belongs to the acyl-CoA dehydrogenase family.Curated

Phylogenomic databases

HOGENOMiHOG000131667.
KOiK00257.
OMAiEGSTEIM.
OrthoDBiEOG600DMX.

Family and domain databases

Gene3Di1.10.540.10. 1 hit.
InterProiIPR006091. Acyl-CoA_Oxase/DH_cen-dom.
IPR009075. AcylCo_DH/oxidase_C.
IPR013786. AcylCoA_DH/ox_N.
IPR009100. AcylCoA_DH/oxidase_NM_dom.
[Graphical view]
PfamiPF00441. Acyl-CoA_dh_1. 1 hit.
PF02770. Acyl-CoA_dh_M. 1 hit.
PF02771. Acyl-CoA_dh_N. 1 hit.
[Graphical view]
SUPFAMiSSF47203. SSF47203. 1 hit.
SSF56645. SSF56645. 1 hit.

Sequencei

Sequence statusi: Complete.

P63430-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQQTQVTEE QARALAEESR ESGWDKPSFA KELFLGRFPL GLIHPFPKPS
60 70 80 90 100
DAEEARTEAF LVKLREFLDT VDGSVIERAA QIPDEYVKGL AELGCFGLKI
110 120 130 140 150
PSEYGGLNMS QVAYNRVLMM VTTVHSSLGA LLSAHQSIGV PEPLKLAGTA
160 170 180 190 200
EQKRRFLPRC AAGAISAFLL TEPDVGSDPA RMASTATPID DGQAYELEGV
210 220 230 240 250
KLWTTNGVVA DLLVVMARVP RSEGHRGGIS AFVVEADSPG ITVERRNKFM
260 270 280 290 300
GLRGIENGVT RLHRVRVPKD NLIGREGDGL KIALTTLNAG RLSLPAIATG
310 320 330 340 350
VAKQALKIAR EWSVERVQWG KPVGQHEAVA SKISFIAATN YALDAVVELS
360 370 380 390 400
SQMADEGRND IRIEAALAKL WSSEMACLVG DELLQIRGGR GYETAESLAA
410 420 430 440 450
RGERAVPVEQ MVRDLRINRI FEGSSEIMRL LIAREAVDAH LTAAGDLANP
460 470 480 490 500
KADLRQKAAA AAGASGFYAK WLPKLVFGEG QLPTTYREFG ALATHLRFVE
510 520 530 540 550
RSSRKLARNT FYGMARWQAS LEKKQGFLGR IVDIGAELFA ISAACVRAEA
560 570 580 590 600
QRTADPVEGE QAYELAEAFC QQATLRVEAL FDALWSNTDS IDVRLANDVL
610 620 630 640 650
EGRYTWLEQG ILDQSEGTGP WIASWEPGPS TEANLARRFL TVSPSSEAKL
Length:650
Mass (Da):70,745
Last modified:October 11, 2004 - v1
Checksum:iFECF934A3F01C0D1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX248333 Genomic DNA. Translation: CDO42141.1.
RefSeqiNP_854554.1. NC_002945.3.
WP_003898626.1. NC_002945.3.

Genome annotation databases

EnsemblBacteriaiCDO42141; CDO42141; Mb0897.
GeneIDi1092772.
KEGGimbo:Mb0897.
PATRICi18003636. VBIMycBov88188_0976.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX248333 Genomic DNA. Translation: CDO42141.1.
RefSeqiNP_854554.1. NC_002945.3.
WP_003898626.1. NC_002945.3.

3D structure databases

ProteinModelPortaliP63430.
SMRiP63430. Positions 25-587.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCDO42141; CDO42141; Mb0897.
GeneIDi1092772.
KEGGimbo:Mb0897.
PATRICi18003636. VBIMycBov88188_0976.

Phylogenomic databases

HOGENOMiHOG000131667.
KOiK00257.
OMAiEGSTEIM.
OrthoDBiEOG600DMX.

Family and domain databases

Gene3Di1.10.540.10. 1 hit.
InterProiIPR006091. Acyl-CoA_Oxase/DH_cen-dom.
IPR009075. AcylCo_DH/oxidase_C.
IPR013786. AcylCoA_DH/ox_N.
IPR009100. AcylCoA_DH/oxidase_NM_dom.
[Graphical view]
PfamiPF00441. Acyl-CoA_dh_1. 1 hit.
PF02770. Acyl-CoA_dh_M. 1 hit.
PF02771. Acyl-CoA_dh_N. 1 hit.
[Graphical view]
SUPFAMiSSF47203. SSF47203. 1 hit.
SSF56645. SSF56645. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-935 / AF2122/97.

Entry informationi

Entry nameiY897_MYCBO
AccessioniPrimary (citable) accession number: P63430
Secondary accession number(s): O53885, Q10535, X2BGE3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: November 11, 2015
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.