Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative acetyl-coenzyme A carboxylase carboxyl transferase subunit beta

Gene

accD3

Organism
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.By similarity

Catalytic activityi

ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigase
Biological processFatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (EC:6.4.1.2)
Short name:
ACCase beta chain
Gene namesi
Name:accD3
Ordered Locus Names:BQ2027_MB0928C
OrganismiMycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Taxonomic identifieri233413 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001419 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001997741 – 495Putative acetyl-coenzyme A carboxylase carboxyl transferase subunit betaAdd BLAST495

Structurei

3D structure databases

ProteinModelPortaliP63406.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 236CoA carboxyltransferase N-terminalPROSITE-ProRule annotationAdd BLAST236
Domaini242 – 470CoA carboxyltransferase C-terminalPROSITE-ProRule annotationAdd BLAST229

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni1 – 470CarboxyltransferasePROSITE-ProRule annotationAdd BLAST470

Sequence similaritiesi

Belongs to the AccD/PCCB family.Curated

Phylogenomic databases

HOGENOMiHOG000244564.
KOiK01962.
K01963.
OMAiAVIACEF.

Family and domain databases

InterProiView protein in InterPro
IPR034733. AcCoA_carboxyl.
IPR000438. Acetyl_CoA_COase_Trfase_b_su.
IPR029045. ClpP/crotonase-like_dom.
IPR011763. COA_CT_C.
IPR011762. COA_CT_N.
PfamiView protein in Pfam
PF01039. Carboxyl_trans. 1 hit.
PRINTSiPR01070. ACCCTRFRASEB.
SUPFAMiSSF52096. SSF52096. 2 hits.
PROSITEiView protein in PROSITE
PS50989. COA_CT_CTER. 1 hit.
PS50980. COA_CT_NTER. 1 hit.

Sequencei

Sequence statusi: Complete.

P63406-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRITTDQLR HAVLDRGSFV SWDSEPLAVP VADSYARELA AARAATGADE
60 70 80 90 100
SVQTGEGRVF GRRVAVVACE FDFLGGSIGV AAAERITAAV ERATAERLPL
110 120 130 140 150
LASPSSGGTR MQEGTVAFLQ MVKIAAAIQL HNQARLPYLV YLRHPTTGGV
160 170 180 190 200
FASWGSLGHL TVAEPGALIG FLGPRVYELL YGDPFPSGVQ TAENLRRHGI
210 220 230 240 250
IDGVVALDRL RPMLDRALTV LIDAPEPLPA PQTPAPVPDV PTWDSVVASR
260 270 280 290 300
RPDRPGVRQL LRHGATDRVL LSGTDQGEAA TTLLALARFG GQPTVVLGQQ
310 320 330 340 350
RAVGGGGSTV GPAALREARR GMALAAELCL PLVLVIDAAG PALSAAAEQG
360 370 380 390 400
GLAGQIAHCL AELVTLDTPT VSILLGQGSG GPALAMLPAD RVLAALHGWL
410 420 430 440 450
APLPPEGASA IVFRDTAHAA ELAAAQGIRS ADLLKSGIVD TIVPEYPDAA
460 470 480 490
DEPIEFALRL SNAIAAEVHA LRKIPAPERL ATRLQRYRRI GLPRD
Length:495
Mass (Da):51,772
Last modified:October 11, 2004 - v1
Checksum:i156C96E927FF950C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LT708304 Genomic DNA. Translation: SIT99526.1.
RefSeqiNP_854585.1. NC_002945.3.
WP_003404691.1. NC_002945.4.

Genome annotation databases

EnsemblBacteriaiCDO42172; CDO42172; Mb0928c.
KEGGimbo:Mb0928c.
PATRICifig|233413.5.peg.1009.

Similar proteinsi

Entry informationi

Entry nameiACCD_MYCBO
AccessioniPrimary (citable) accession number: P63406
Secondary accession number(s): A0A1R3XWS2, Q10561, X2BG50
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: August 30, 2017
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families