P63340 (YQEG_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Inner membrane transport protein YqeG

Gene names

Name:	yqeG
Ordered Locus Names:	b2845, JW2813

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	409 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Cell inner membrane; Multi-pass membrane protein.
Sequence similarities	Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.

Ontologies

Keywords
Biological process	Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 409	409	Inner membrane transport protein YqeG		PRO_0000093814
Regions
	Topological domain	1 – 25	25	Periplasmic Potential
	Transmembrane	26 – 46	21	Helical; Potential
	Topological domain	47 – 87	41	Cytoplasmic Potential
	Transmembrane	88 – 108	21	Helical; Potential
	Topological domain	109 – 127	19	Periplasmic Potential
	Transmembrane	128 – 148	21	Helical; Potential
	Topological domain	149 – 151	3	Cytoplasmic Potential
	Transmembrane	152 – 172	21	Helical; Potential
	Topological domain	173 – 193	21	Periplasmic Potential
	Transmembrane	194 – 214	21	Helical; Potential
	Topological domain	215 – 235	21	Cytoplasmic Potential
	Transmembrane	236 – 256	21	Helical; Potential
	Topological domain	257 – 276	20	Periplasmic Potential
	Transmembrane	277 – 297	21	Helical; Potential
	Topological domain	298 – 329	32	Cytoplasmic Potential
	Transmembrane	330 – 350	21	Helical; Potential
	Topological domain	351 – 353	3	Periplasmic Potential
	Transmembrane	354 – 374	21	Helical; Potential
	Topological domain	375 – 388	14	Cytoplasmic Potential
	Transmembrane	389 – 409	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	P63340 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: 3CBFF3E7D4CC5539	FASTA	409	45,099
	10 20 30 40 50 60 MSNIWSKEET LWSFALYGTA VGAGTLFLPI QLGSAGAVVL FITALVAWPL TYWPHKALCQ 70 80 90 100 110 120 FILSSKTSAG EGITGAVTHY YGKKIGNLIT TLYFIAFFVV VLIYAVAITN SLTEQLAKHM 130 140 150 160 170 180 VIDLRIRMLV SLGVVLILNL IFLMGRHATI RVMGFLVFPL IAYFLFLSIY LVGSWQPDLL 190 200 210 220 230 240 TTQVEFNQNT LHQIWISIPV MVFAFSHTPI ISTFAIDRRE KYGEHAMDKC KKIMKVAYLI 250 260 270 280 290 300 ICISVLFFVF SCLLSIPPSY IEAAKEEGVT ILSALSMLPN APAWLSISGI IVAVVAMSKS 310 320 330 340 350 360 FLGTYFGVIE GATEVVKTTL QQVGVKKSRA FNRALSIMLV SLITFIVCCI NPNAISMIYA 370 380 390 400 ISGPLIAMIL FIMPTLSTYL IPALKPWRSI GNLITLIVGI LCVSVMFFS

References

[1]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[2]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[3]	"Global topology analysis of the Escherichia coli inner membrane proteome." Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G. Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract] Cited for: TOPOLOGY [LARGE SCALE ANALYSIS]. Strain: K12 / MG1655 / ATCC 47076.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U29581 Genomic DNA. Translation: AAB40492.1. U00096 Genomic DNA. Translation: AAC75884.1. AP009048 Genomic DNA. Translation: BAE76914.1.
PIR	F65067.
RefSeq	NP_417322.1. NC_000913.2. YP_491050.1. NC_007779.1.
3D structure databases
ProteinModelPortal	P63340.
ModBase	Search...
Protein-protein interaction databases
STRING	511145.b2845.
Proteomic databases
PRIDE	P63340.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC75884; AAC75884; b2845. BAE76914; BAE76914; BAE76914.
GeneID	12934519. 945028.
KEGG	ecj:Y75_p2779. eco:b2845.
PATRIC	32121108. VBIEscCol129921_2943.
Organism-specific databases
EchoBASE	EB2901.
EcoGene	EG13098. yqeG.
Phylogenomic databases
eggNOG	COG0814.
HOGENOM	HOG000270787.
OMA	VVCCINP.
ProtClustDB	CLSK880505.
Enzyme and pathway databases
BioCyc	EcoCyc:B2845-MONOMER. ECOL316407:JW2813-MONOMER.
Gene expression databases
Genevestigator	P63340.
Family and domain databases
InterPro	IPR018227. Tryptophan/tyrosine_permease. [Graphical view]
Pfam	PF03222. Trp_Tyr_perm. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YQEG_ECOLI

Accession

Primary (citable) accession number: P63340
Secondary accession number(s): Q2M9Z2, Q46940

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 11, 2004
Last sequence update:	October 11, 2004
Last modified:	May 1, 2013
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program