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P63337 (6PGL_NEIMB) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
6-phosphogluconolactonase
Short name=6PGL
EC=3.1.1.31
Gene names
Name:pgl
Ordered Locus Names:NMB1391
OrganismNeisseria meningitidis serogroup B
Taxonomic identifier491 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria

Protein attributes

Sequence length231 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

Catalytic activity

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.

Sequence similarities

Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processpentose-phosphate shunt

Inferred from electronic annotation. Source: InterPro

   Molecular function6-phosphogluconolactonase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2312316-phosphogluconolactonase
PRO_0000090098

Sequences

Sequence LengthMass (Da)Tools
P63337 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 5EF54C495553D073

FASTA23124,980
        10         20         30         40         50         60 
MFVWHEYENA AEAAQSLADA VADALQGALD EKGGAVLAVS GGRSPIAFFN ALSQKDLDWK 

        70         80         90        100        110        120 
NVGITLADER IVPTVHADSN TGLVREYLLK NKAEAAMWIP MVEDGKTETE LHPDAVVDYA 

       130        140        150        160        170        180 
LKHYKQPDVL VLGMGNDGHT ASIFPKAPQF QTAIDGSAGV ALVHTTPVTA PHERVSMTLD 

       190        200        210        220        230 
AIAHTGHVFL AIRGEEKKAV FDQAAQGENR EYPINLVLNH QGVNCHVFYA E

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE002098 Genomic DNA. Translation: AAF41755.1.
PIRF81089.
RefSeqNP_274405.1. NC_003112.2.

3D structure databases

ProteinModelPortalP63337.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBNEIT00000010393; EBNEIP00000010013; EBNEIG00000010393.
GeneID903813.
GenomeReviewsGene locus NMB1391 in contig AE002098_GR.
KEGGnme:NMB1391.
PATRIC20358465. VBINeiMen85645_1744.
TIGRNMB1391.

Phylogenomic databases

GeneTreeEBGT00050000021469.
HOGENOMHBG725991.
OMARLTFTFS.
ProtClustDBCLSK878040.

Enzyme and pathway databases

BioCycNMEN122586:NMB_1391-MONOMER.

Family and domain databases

InterProIPR005900. 6-phosphogluconolactonase_DevB.
IPR006148. Glc/Gal-6P_isomerase.
[Graphical view]
KOK01057.
PfamPF01182. Glucosamine_iso. 1 hit.
[Graphical view]
TIGRFAMsTIGR01198. Pgl. 1 hit.
ProtoNetSearch...

Entry information

Entry name6PGL_NEIMB
AccessionPrimary (citable) accession number: P63337
Secondary accession number(s): Q9JR64
Entry history
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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