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P63276

- RS17_MOUSE

UniProt

P63276 - RS17_MOUSE

Protein

40S ribosomal protein S17

Gene

Rps17

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. structural constituent of ribosome Source: MGI

    GO - Biological processi

    1. ribosomal small subunit assembly Source: RefGenome
    2. translation Source: MGI
    3. translational elongation Source: RefGenome

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Enzyme and pathway databases

    ReactomeiREACT_196445. SRP-dependent cotranslational protein targeting to membrane.
    REACT_198524. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_198528. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    40S ribosomal protein S17
    Gene namesi
    Name:Rps17
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 7

    Organism-specific databases

    MGIiMGI:1309526. Rps17.

    Subcellular locationi

    GO - Cellular componenti

    1. cytosolic small ribosomal subunit Source: MGI

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11RemovedBy similarity
    Chaini2 – 13513440S ribosomal protein S17PRO_0000141526Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei19 – 191N6-succinyllysine1 Publication
    Modified residuei113 – 1131PhosphoserineBy similarity
    Modified residuei130 – 1301PhosphothreonineBy similarity

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiP63276.
    PaxDbiP63276.
    PRIDEiP63276.

    PTM databases

    PhosphoSiteiP63276.

    Expressioni

    Gene expression databases

    ArrayExpressiP63276.
    BgeeiP63276.
    CleanExiMM_RPS17.
    GenevestigatoriP63276.

    Interactioni

    Protein-protein interaction databases

    BioGridi203005. 9 interactions.

    Structurei

    3D structure databases

    ProteinModelPortaliP63276.
    SMRiP63276. Positions 1-126.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein S17e family.Curated

    Phylogenomic databases

    eggNOGiCOG1383.
    HOVERGENiHBG001708.
    InParanoidiP63276.
    KOiK02962.
    OMAiFTTHLMR.
    OrthoDBiEOG72C52C.
    PhylomeDBiP63276.
    TreeFamiTF317992.

    Family and domain databases

    Gene3Di1.10.60.20. 1 hit.
    HAMAPiMF_00511. Ribosomal_S17e.
    InterProiIPR001210. Ribosomal_S17e.
    IPR018273. Ribosomal_S17e_CS.
    [Graphical view]
    PANTHERiPTHR10732. PTHR10732. 1 hit.
    PfamiPF00833. Ribosomal_S17e. 1 hit.
    [Graphical view]
    SUPFAMiSSF116820. SSF116820. 1 hit.
    PROSITEiPS00712. RIBOSOMAL_S17E. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P63276-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGRVRTKTVK KAARVIIEKY YTRLGNDFHT NKRVCEEIAI IPSKKLRNKI    50
    AGYVTHLMKR IQRGPVRGIS IKLQEEERER RDNYVPEVSA LDQEIIEVDP 100
    DTKEMLKLLD FGSLSNLQVT QPTVGMNFKT PRGAV 135
    Length:135
    Mass (Da):15,524
    Last modified:January 23, 2007 - v2
    Checksum:i29806605C5401325
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D25213 mRNA. Translation: BAA04943.1.
    AK007992 mRNA. Translation: BAB25394.1.
    AK010647 mRNA. Translation: BAB27087.1.
    BC002044 mRNA. No translation available.
    BC081466 mRNA. Translation: AAH81466.1.
    CCDSiCCDS40006.1.
    RefSeqiNP_033118.1. NM_009092.3.
    UniGeneiMm.42767.
    Mm.431314.

    Genome annotation databases

    EnsembliENSMUST00000080813; ENSMUSP00000079628; ENSMUSG00000061787.
    GeneIDi20068.
    KEGGimmu:20068.
    UCSCiuc009ibv.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D25213 mRNA. Translation: BAA04943.1 .
    AK007992 mRNA. Translation: BAB25394.1 .
    AK010647 mRNA. Translation: BAB27087.1 .
    BC002044 mRNA. No translation available.
    BC081466 mRNA. Translation: AAH81466.1 .
    CCDSi CCDS40006.1.
    RefSeqi NP_033118.1. NM_009092.3.
    UniGenei Mm.42767.
    Mm.431314.

    3D structure databases

    ProteinModelPortali P63276.
    SMRi P63276. Positions 1-126.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 203005. 9 interactions.

    PTM databases

    PhosphoSitei P63276.

    Proteomic databases

    MaxQBi P63276.
    PaxDbi P63276.
    PRIDEi P63276.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000080813 ; ENSMUSP00000079628 ; ENSMUSG00000061787 .
    GeneIDi 20068.
    KEGGi mmu:20068.
    UCSCi uc009ibv.1. mouse.

    Organism-specific databases

    CTDi 6218.
    MGIi MGI:1309526. Rps17.

    Phylogenomic databases

    eggNOGi COG1383.
    HOVERGENi HBG001708.
    InParanoidi P63276.
    KOi K02962.
    OMAi FTTHLMR.
    OrthoDBi EOG72C52C.
    PhylomeDBi P63276.
    TreeFami TF317992.

    Enzyme and pathway databases

    Reactomei REACT_196445. SRP-dependent cotranslational protein targeting to membrane.
    REACT_198524. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_198528. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

    Miscellaneous databases

    NextBioi 297571.
    PROi P63276.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi P63276.
    Bgeei P63276.
    CleanExi MM_RPS17.
    Genevestigatori P63276.

    Family and domain databases

    Gene3Di 1.10.60.20. 1 hit.
    HAMAPi MF_00511. Ribosomal_S17e.
    InterProi IPR001210. Ribosomal_S17e.
    IPR018273. Ribosomal_S17e_CS.
    [Graphical view ]
    PANTHERi PTHR10732. PTHR10732. 1 hit.
    Pfami PF00833. Ribosomal_S17e. 1 hit.
    [Graphical view ]
    SUPFAMi SSF116820. SSF116820. 1 hit.
    PROSITEi PS00712. RIBOSOMAL_S17E. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The nucleotide sequence of a cDNA clone encoding ribosomal protein S17 of Ehrlich ascites carcinoma cells."
      Karasaki Y., Satoh Y., Ohji T., Tsukamoto S., Higashi K., Gotoh S., Mizusaki K.
      Biochem. Genet. 32:409-414(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: ddY.
    2. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J.
      Tissue: Pancreas.
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6.
      Tissue: Brain and Mammary tumor.
    4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Embryonic brain.
    5. "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
      Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J.
      Mol. Cell. Proteomics 8:904-912(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Embryonic fibroblast.
    6. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
      Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUCCINYLATION [LARGE SCALE ANALYSIS] AT LYS-19, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Embryonic fibroblast.

    Entry informationi

    Entry nameiRS17_MOUSE
    AccessioniPrimary (citable) accession number: P63276
    Secondary accession number(s): P06584
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 1, 1988
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 87 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3