##gff-version 3
P63241	UniProtKB	Initiator methionine	1	1	.	.	.	Note=Removed;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:10229683,ECO:0000269|Ref.10;Dbxref=PMID:10229683	
P63241	UniProtKB	Chain	2	154	.	.	.	ID=PRO_0000142451;Note=Eukaryotic translation initiation factor 5A-1	
P63241	UniProtKB	Region	20	90	.	.	.	Note=Interaction with DOHH;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17213197;Dbxref=PMID:17213197	
P63241	UniProtKB	Modified residue	2	2	.	.	.	Note=N-acetylalanine;Ontology_term=ECO:0000269;evidence=ECO:0000269|Ref.10	
P63241	UniProtKB	Modified residue	47	47	.	.	.	Note=N6-acetyllysine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19379712;Dbxref=PMID:19379712	
P63241	UniProtKB	Modified residue	50	50	.	.	.	Note=Hypusine;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:27306458,ECO:0000269|PubMed:3095320;Dbxref=PMID:27306458,PMID:3095320	
P63241	UniProtKB	Modified residue	121	121	.	.	.	Note=N6-acetyllysine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P63242	
P63241	UniProtKB	Alternative sequence	1	2	.	.	.	ID=VSP_022020;Note=In isoform 2. MA->MCGTGGTDSKTRRPPHRASFLKRLESKPLKMA;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.5	
P63241	UniProtKB	Natural variant	48	48	.	.	.	ID=VAR_085973;Note=In FABAS%3B in yeast%2C exhibits reduced ribosome binding%2C reduced levels of hypusination and transfected cells show impaired synthesis of proteins containing poly-proline tracts. T->N;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:33547280;Dbxref=PMID:33547280	
P63241	UniProtKB	Natural variant	106	106	.	.	.	ID=VAR_085974;Note=In FABAS%3B in yeast%2C exhibits reduced ribosome binding and cells show impaired synthesis of proteins containing poly-proline tracts. G->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:33547280;Dbxref=PMID:33547280	
P63241	UniProtKB	Natural variant	109	154	.	.	.	ID=VAR_085975;Note=In FABAS. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:33547280;Dbxref=PMID:33547280	
P63241	UniProtKB	Natural variant	109	109	.	.	.	ID=VAR_085976;Note=In FABAS. R->G;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:33547280;Dbxref=PMID:33547280	
P63241	UniProtKB	Natural variant	115	115	.	.	.	ID=VAR_085977;Note=In FABAS. P->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:33547280;Dbxref=PMID:33547280	
P63241	UniProtKB	Natural variant	122	122	.	.	.	ID=VAR_085978;Note=In FABAS%3B in yeast%2C exhibits reduced ribosome binding and cells show impaired synthesis of proteins containing poly-proline tracts. E->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:33547280;Dbxref=PMID:33547280	
P63241	UniProtKB	Mutagenesis	47	47	.	.	.	Note=Abolishes acetylation. K->A%2CR;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:18067580,ECO:0000269|PubMed:19379712;Dbxref=PMID:18067580,PMID:19379712	
P63241	UniProtKB	Mutagenesis	47	47	.	.	.	Note=Causes total inactivation of eIF5A in supporting yeast growth. K->D;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:18067580,ECO:0000269|PubMed:19379712;Dbxref=PMID:18067580,PMID:19379712	
P63241	UniProtKB	Mutagenesis	49	49	.	.	.	Note=Causes total inactivation of eIF5A in supporting yeast growth. G->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:18067580;Dbxref=PMID:18067580	
P63241	UniProtKB	Mutagenesis	50	50	.	.	.	Note=Decreases significantly the acetylation at position K-47 and causes total inactivation of eIF5A in supporting yeast growth. K->A;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:17187778,ECO:0000269|PubMed:18067580,ECO:0000269|PubMed:19379712;Dbxref=PMID:17187778,PMID:18067580,PMID:19379712	
P63241	UniProtKB	Mutagenesis	50	50	.	.	.	Note=Causes total inactivation of eIF5A in supporting yeast growth. K->I%2CD%2CR;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:17187778,ECO:0000269|PubMed:18067580,ECO:0000269|PubMed:19379712;Dbxref=PMID:17187778,PMID:18067580,PMID:19379712	
P63241	UniProtKB	Mutagenesis	52	52	.	.	.	Note=Causes total inactivation of eIF5A in supporting yeast growth. G->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:18067580;Dbxref=PMID:18067580	
P63241	UniProtKB	Mutagenesis	55	55	.	.	.	Note=Causes total inactivation of eIF5A in supporting yeast growth. K->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:18067580;Dbxref=PMID:18067580	
P63241	UniProtKB	Mutagenesis	81	81	.	.	.	Note=Leads to temperature sensitivity when expressed in yeast cells. V->G;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16987817;Dbxref=PMID:16987817	
P63241	UniProtKB	Sequence conflict	36	36	.	.	.	Note=R->W;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P63241	UniProtKB	Sequence conflict	45	45	.	.	.	Note=T->A;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P63241	UniProtKB	Sequence conflict	85	85	.	.	.	Note=K->R;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P63241	UniProtKB	Sequence conflict	109	109	.	.	.	Note=R->P;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P63241	UniProtKB	Beta strand	17	21	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3CPF	
P63241	UniProtKB	Helix	22	24	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3CPF	
P63241	UniProtKB	Beta strand	29	33	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3CPF	
P63241	UniProtKB	Beta strand	36	46	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3CPF	
P63241	UniProtKB	Beta strand	55	62	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3CPF	
P63241	UniProtKB	Turn	63	65	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3CPF	
P63241	UniProtKB	Beta strand	68	74	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3CPF	
P63241	UniProtKB	Beta strand	77	82	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3CPF	
P63241	UniProtKB	Beta strand	85	95	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3CPF	
P63241	UniProtKB	Beta strand	98	102	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3CPF	
P63241	UniProtKB	Helix	117	129	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3CPF	
P63241	UniProtKB	Beta strand	134	140	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3CPF	
P63241	UniProtKB	Beta strand	143	150	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3CPF