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Protein

BarH-like 1 homeobox protein

Gene

Barhl1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi178 – 237HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
BarH-like 1 homeobox protein
Alternative name(s):
Bar-class homeodomain protein MBH2
BarH-related homeobox protein 1
Gene namesi
Name:Barhl1
Synonyms:Mbh2
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 3

Organism-specific databases

RGDi620648. Barhl1.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000488281 – 327BarH-like 1 homeobox proteinAdd BLAST327

Proteomic databases

PaxDbiP63156.

Expressioni

Gene expression databases

BgeeiENSRNOG00000013209.
GenevisibleiP63156. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000017725.

Structurei

3D structure databases

ProteinModelPortaliP63156.
SMRiP63156.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the BAR homeobox family.Curated

Keywords - Domaini

Homeobox

Phylogenomic databases

eggNOGiKOG0488. Eukaryota.
ENOG411188D. LUCA.
GeneTreeiENSGT00870000136368.
HOGENOMiHOG000231533.
HOVERGENiHBG050663.
InParanoidiP63156.
KOiK09360.
OMAiSDSEYKG.
OrthoDBiEOG091G13SM.
PhylomeDBiP63156.
TreeFamiTF316128.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
PfamiView protein in Pfam
PF00046. Homeobox. 1 hit.
PRINTSiPR00024. HOMEOBOX.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiView protein in PROSITE
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

P63156-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGSNGFGID SILSHRAGSP ALPKGDPLLG DCRSPLELSP RSESSSDCSS
60 70 80 90 100
PASPGRDCLE TSTSRPGAAS GPGLDSHLQP GQLSAPAQSR TVTSSFLIRD
110 120 130 140 150
ILADCKPLAA CAPYSSSGQP AAPEPGGRLA AKAGEDFRDK LDKSVSSASS
160 170 180 190 200
DSEYKVKEEG DREISSSRDS PPVRLKKPRK ARTAFTDHQL AQLERSFERQ
210 220 230 240 250
KYLSVQDRME LAASLNLTDT QVKTWYQNRR TKWKRQTAVG LELLAEAGNY
260 270 280 290 300
SALQRMFPSP YFYPQSLVSN LDPGAALYLY RGPSAPPPAL QRPLVPRILI
310 320
HGLQGASEPP PPLPPLPGVL PRAAQPR
Length:327
Mass (Da):35,136
Last modified:September 27, 2004 - v1
Checksum:i4130725E55D322FD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB043981 mRNA. Translation: BAB18600.1.
RefSeqiNP_476450.1. NM_057109.1.
UniGeneiRn.162655.

Genome annotation databases

EnsembliENSRNOT00000017725; ENSRNOP00000017725; ENSRNOG00000013209.
GeneIDi117232.
KEGGirno:117232.
UCSCiRGD:620648. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB043981 mRNA. Translation: BAB18600.1.
RefSeqiNP_476450.1. NM_057109.1.
UniGeneiRn.162655.

3D structure databases

ProteinModelPortaliP63156.
SMRiP63156.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000017725.

Proteomic databases

PaxDbiP63156.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000017725; ENSRNOP00000017725; ENSRNOG00000013209.
GeneIDi117232.
KEGGirno:117232.
UCSCiRGD:620648. rat.

Organism-specific databases

CTDi56751.
RGDi620648. Barhl1.

Phylogenomic databases

eggNOGiKOG0488. Eukaryota.
ENOG411188D. LUCA.
GeneTreeiENSGT00870000136368.
HOGENOMiHOG000231533.
HOVERGENiHBG050663.
InParanoidiP63156.
KOiK09360.
OMAiSDSEYKG.
OrthoDBiEOG091G13SM.
PhylomeDBiP63156.
TreeFamiTF316128.

Miscellaneous databases

PROiPR:P63156.

Gene expression databases

BgeeiENSRNOG00000013209.
GenevisibleiP63156. RN.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
PfamiView protein in Pfam
PF00046. Homeobox. 1 hit.
PRINTSiPR00024. HOMEOBOX.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiView protein in PROSITE
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiBARH1_RAT
AccessioniPrimary (citable) accession number: P63156
Secondary accession number(s): Q9JK26
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 27, 2004
Last sequence update: September 27, 2004
Last modified: March 15, 2017
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.