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Protein

60S ribosomal protein L39

Gene

Rpl39

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-MMU-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-MMU-6791226. Major pathway of rRNA processing in the nucleolus.
R-MMU-72689. Formation of a pool of free 40S subunits.
R-MMU-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-MMU-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-MMU-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L39
Gene namesi
Name:Rpl39
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:1914498. Rpl39.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 515060S ribosomal protein L39PRO_0000127025Add
BLAST

Proteomic databases

EPDiP62892.
PaxDbiP62892.
PeptideAtlasiP62892.
PRIDEiP62892.
TopDownProteomicsiP62892.

PTM databases

iPTMnetiP62892.
PhosphoSiteiP62892.

Expressioni

Gene expression databases

BgeeiP62892.
CleanExiMM_RPL39.
ExpressionAtlasiP62892. baseline and differential.
GenevisibleiP62892. MM.

Interactioni

Subunit structurei

Interacts with IMPACT (PubMed:22404850).1 Publication

Protein-protein interaction databases

BioGridi212046. 1 interaction.
STRINGi10090.ENSMUSP00000110886.

Structurei

3D structure databases

ProteinModelPortaliP62892.
SMRiP62892. Positions 1-37.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L39e family.Curated

Phylogenomic databases

eggNOGiKOG0002. Eukaryota.
COG2167. LUCA.
HOVERGENiHBG001245.
InParanoidiP62892.
KOiK02924.
OMAiARQNRPI.
OrthoDBiEOG789CF5.
PhylomeDBiP62892.
TreeFamiTF300223.

Family and domain databases

Gene3Di1.10.1620.10. 1 hit.
HAMAPiMF_00629. Ribosomal_L39e.
InterProiIPR000077. Ribosomal_L39.
IPR020083. Ribosomal_L39_CS.
IPR023626. Ribosomal_L39e_dom.
[Graphical view]
PANTHERiPTHR19970. PTHR19970. 1 hit.
PfamiPF00832. Ribosomal_L39. 1 hit.
[Graphical view]
SUPFAMiSSF48662. SSF48662. 1 hit.
PROSITEiPS00051. RIBOSOMAL_L39E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P62892-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSHKTFRIK RFLAKKQKQN RPIPQWIRMK TGNKIRYNSK RRHWRRTKLG

L
Length:51
Mass (Da):6,407
Last modified:January 23, 2007 - v2
Checksum:i2023CA8590C7752C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK002591 mRNA. Translation: BAB22212.1.
AK005511 mRNA. Translation: BAB24090.1.
AK007821 mRNA. Translation: BAB25284.1.
AK008853 mRNA. Translation: BAB25930.1.
AK013381 mRNA. Translation: BAB28820.1.
AK028139 mRNA. Translation: BAC25767.1.
AK088761 mRNA. Translation: BAC40552.1.
BC039092 mRNA. Translation: AAH39092.1.
CCDSiCCDS40927.1.
RefSeqiNP_080331.1. NM_026055.2.
UniGeneiMm.30478.

Genome annotation databases

EnsembliENSMUST00000115231; ENSMUSP00000110886; ENSMUSG00000079641.
GeneIDi67248.
KEGGimmu:67248.
UCSCiuc009syc.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK002591 mRNA. Translation: BAB22212.1.
AK005511 mRNA. Translation: BAB24090.1.
AK007821 mRNA. Translation: BAB25284.1.
AK008853 mRNA. Translation: BAB25930.1.
AK013381 mRNA. Translation: BAB28820.1.
AK028139 mRNA. Translation: BAC25767.1.
AK088761 mRNA. Translation: BAC40552.1.
BC039092 mRNA. Translation: AAH39092.1.
CCDSiCCDS40927.1.
RefSeqiNP_080331.1. NM_026055.2.
UniGeneiMm.30478.

3D structure databases

ProteinModelPortaliP62892.
SMRiP62892. Positions 1-37.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi212046. 1 interaction.
STRINGi10090.ENSMUSP00000110886.

PTM databases

iPTMnetiP62892.
PhosphoSiteiP62892.

Proteomic databases

EPDiP62892.
PaxDbiP62892.
PeptideAtlasiP62892.
PRIDEiP62892.
TopDownProteomicsiP62892.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000115231; ENSMUSP00000110886; ENSMUSG00000079641.
GeneIDi67248.
KEGGimmu:67248.
UCSCiuc009syc.1. mouse.

Organism-specific databases

CTDi6170.
MGIiMGI:1914498. Rpl39.

Phylogenomic databases

eggNOGiKOG0002. Eukaryota.
COG2167. LUCA.
HOVERGENiHBG001245.
InParanoidiP62892.
KOiK02924.
OMAiARQNRPI.
OrthoDBiEOG789CF5.
PhylomeDBiP62892.
TreeFamiTF300223.

Enzyme and pathway databases

ReactomeiR-MMU-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-MMU-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-MMU-6791226. Major pathway of rRNA processing in the nucleolus.
R-MMU-72689. Formation of a pool of free 40S subunits.
R-MMU-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-MMU-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-MMU-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

PROiP62892.
SOURCEiSearch...

Gene expression databases

BgeeiP62892.
CleanExiMM_RPL39.
ExpressionAtlasiP62892. baseline and differential.
GenevisibleiP62892. MM.

Family and domain databases

Gene3Di1.10.1620.10. 1 hit.
HAMAPiMF_00629. Ribosomal_L39e.
InterProiIPR000077. Ribosomal_L39.
IPR020083. Ribosomal_L39_CS.
IPR023626. Ribosomal_L39e_dom.
[Graphical view]
PANTHERiPTHR19970. PTHR19970. 1 hit.
PfamiPF00832. Ribosomal_L39. 1 hit.
[Graphical view]
SUPFAMiSSF48662. SSF48662. 1 hit.
PROSITEiPS00051. RIBOSOMAL_L39E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J and NOD.
    Tissue: Kidney, Pancreas, Placenta, Stomach and Thymus.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/N-3.
  3. "Evidence that Yih1 resides in a complex with ribosomes."
    Waller T., Lee S.J., Sattlegger E.
    FEBS J. 279:1761-1776(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH IMPACT.

Entry informationi

Entry nameiRL39_MOUSE
AccessioniPrimary (citable) accession number: P62892
Secondary accession number(s): P02404, P39025, Q9BYF2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2007
Last modified: July 6, 2016
This is version 102 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Miscellaneous

This protein is the smallest and one of the most basic of the proteins in liver ribosomes.By similarity

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.