Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

40S ribosomal protein S24

Gene

Rps24

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.By similarity

GO - Molecular functioni

  • protein complex binding Source: RGD
  • structural constituent of ribosome Source: InterPro
  • translation initiation factor binding Source: UniProtKB

GO - Biological processi

  • liver regeneration Source: RGD
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: GO_Central
  • translational initiation Source: UniProtKB

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-RNO-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-RNO-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-RNO-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.
R-RNO-72649. Translation initiation complex formation.
R-RNO-72689. Formation of a pool of free 40S subunits.
R-RNO-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-RNO-72702. Ribosomal scanning and start codon recognition.
R-RNO-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-RNO-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-RNO-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S24
Gene namesi
Name:Rps24
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 16

Organism-specific databases

RGDi621040. Rps24.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001376261 – 13340S ribosomal protein S24Add BLAST133

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1N-acetylmethionineBy similarity1
Modified residuei9PhosphothreonineBy similarity1
Cross-linki37Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

PaxDbiP62850.
PRIDEiP62850.

PTM databases

iPTMnetiP62850.
PhosphoSitePlusiP62850.
SwissPalmiP62850.

Expressioni

Gene expression databases

BgeeiENSRNOG00000010189.
ExpressionAtlasiP62850. baseline.
GenevisibleiP62850. RN.

Interactioni

GO - Molecular functioni

  • protein complex binding Source: RGD
  • translation initiation factor binding Source: UniProtKB

Protein-protein interaction databases

IntActiP62850. 2 interactors.
MINTiMINT-1845718.
STRINGi10116.ENSRNOP00000048903.

Structurei

3D structure databases

ProteinModelPortaliP62850.
SMRiP62850.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3424. Eukaryota.
COG2004. LUCA.
GeneTreeiENSGT00390000000153.
HOGENOMiHOG000186306.
HOVERGENiHBG000969.
InParanoidiP62850.
KOiK02974.
OMAiTHFGGGR.
OrthoDBiEOG091G0WLL.
PhylomeDBiP62850.
TreeFamiTF314134.

Family and domain databases

HAMAPiMF_00545. Ribosomal_S24e. 1 hit.
InterProiView protein in InterPro
IPR012678. Ribosomal_L23/L15e_core_dom.
IPR001976. Ribosomal_S24e.
IPR018098. Ribosomal_S24e_CS.
PANTHERiPTHR10496. PTHR10496. 1 hit.
PfamiView protein in Pfam
PF01282. Ribosomal_S24e. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD006052. Ribosomal_S24e. 1 hit.
SUPFAMiSSF54189. SSF54189. 1 hit.
PROSITEiView protein in PROSITE
PS00529. RIBOSOMAL_S24E. 1 hit.

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: P62850-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MNDTVTIRTR KFMTNRLLQR KQMVIDVLHP GKATVPKTEI REKLAKMYKT
60 70 80 90 100
TPDVIFVFGF RTHFGGGKTT GFGMIYDSLD YAKKNEPKHR LARHGLYEKK
110 120 130
KTSRKQRKER KNRMKKVRGT AKANVGAGKK PKE
Length:133
Mass (Da):15,423
Last modified:August 16, 2004 - v1
Checksum:iCE9065C0764D60A6
GO
Isoform 2 (identifier: P62850-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     131-133: Missing.

Show »
Length:130
Mass (Da):15,069
Checksum:iE0764D60A6DD576E
GO
Isoform 3 (identifier: P62850-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     131-133: PKE → K

Note: No experimental confirmation available.
Show »
Length:131
Mass (Da):15,197
Checksum:i3190764D60A6DD57
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_011367131 – 133Missing in isoform 2. Curated3
Alternative sequenceiVSP_011368131 – 133PKE → K in isoform 3. 1 Publication3

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X52445 mRNA. Translation: CAA36684.1.
X51538 mRNA. Translation: CAA35918.1.
BC058140 mRNA. Translation: AAH58140.1.
PIRiS09197. R3RT24.
RefSeqiNP_112374.1. NM_031112.1. [P62850-1]
XP_006252593.1. XM_006252531.3. [P62850-3]
XP_006252594.1. XM_006252532.3. [P62850-3]
XP_006252595.1. XM_006252533.2. [P62850-2]
UniGeneiRn.979.

Genome annotation databases

EnsembliENSRNOT00000064788; ENSRNOP00000059382; ENSRNOG00000010189. [P62850-3]
GeneIDi81776.
KEGGirno:81776.
UCSCiRGD:621040. rat. [P62850-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiRS24_RAT
AccessioniPrimary (citable) accession number: P62850
Secondary accession number(s): P16632, Q6PEC9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: August 16, 2004
Last modified: September 27, 2017
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families