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Protein

40S ribosomal protein S24

Gene

RPS24

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.1 Publication

GO - Molecular functioni

  1. nucleotide binding Source: InterPro
  2. poly(A) RNA binding Source: UniProtKB
  3. structural constituent of ribosome Source: UniProtKB
  4. translation initiation factor binding Source: UniProtKB

GO - Biological processi

  1. cellular protein metabolic process Source: Reactome
  2. erythrocyte homeostasis Source: UniProtKB
  3. gene expression Source: Reactome
  4. maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: GO_Central
  5. mRNA metabolic process Source: Reactome
  6. nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Source: Reactome
  7. ribosomal small subunit biogenesis Source: UniProtKB
  8. RNA metabolic process Source: Reactome
  9. rRNA processing Source: UniProtKB
  10. SRP-dependent cotranslational protein targeting to membrane Source: Reactome
  11. translation Source: UniProtKB
  12. translational elongation Source: Reactome
  13. translational initiation Source: Reactome
  14. translational termination Source: Reactome
  15. viral life cycle Source: Reactome
  16. viral process Source: Reactome
  17. viral transcription Source: Reactome
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiREACT_1079. Formation of the ternary complex, and subsequently, the 43S complex.
REACT_115902. SRP-dependent cotranslational protein targeting to membrane.
REACT_1404. Peptide chain elongation.
REACT_1797. Formation of a pool of free 40S subunits.
REACT_1979. Translation initiation complex formation.
REACT_1986. Eukaryotic Translation Termination.
REACT_2085. GTP hydrolysis and joining of the 60S ribosomal subunit.
REACT_75768. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
REACT_75822. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
REACT_79. L13a-mediated translational silencing of Ceruloplasmin expression.
REACT_931. Ribosomal scanning and start codon recognition.
REACT_9491. Viral mRNA Translation.

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S24
Gene namesi
Name:RPS24
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 10

Organism-specific databases

HGNCiHGNC:10411. RPS24.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: HPA
  2. cytosol Source: Reactome
  3. cytosolic small ribosomal subunit Source: UniProtKB
  4. membrane Source: UniProtKB
  5. nucleolus Source: GO_Central
  6. nucleus Source: UniProtKB
  7. small ribosomal subunit Source: UniProtKB
Complete GO annotation...

Pathology & Biotechi

Involvement in diseasei

Diamond-Blackfan anemia 31 Publication

The disease is caused by mutations affecting the gene represented in this entry.

Disease descriptionA form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of developing leukemia. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies.

See also OMIM:610629

Keywords - Diseasei

Diamond-Blackfan anemia

Organism-specific databases

MIMi610629. phenotype.
Orphaneti124. Blackfan-Diamond anemia.
PharmGKBiPA34815.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 13313340S ribosomal protein S24PRO_0000137623Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylmethionine4 Publications
Modified residuei9 – 91Phosphothreonine1 Publication

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiP62847.
PaxDbiP62847.
PRIDEiP62847.

PTM databases

PhosphoSiteiP62847.

Expressioni

Tissue specificityi

Mature tissues, such as adult brain, skeletal muscle, heart, and kidney, express low levels, whereas tissues and organs with significant populations of proliferating cells, such as fetal brain, placenta, bone marrow, and various glandular organs, contain significantly higher levels.1 Publication

Gene expression databases

BgeeiP62847.
CleanExiHS_RPS24.
ExpressionAtlasiP62847. baseline and differential.
GenevestigatoriP62847.

Organism-specific databases

HPAiHPA003364.

Interactioni

Protein-protein interaction databases

BioGridi112143. 145 interactions.
IntActiP62847. 22 interactions.
MINTiMINT-4719640.
STRINGi9606.ENSP00000414321.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4V6Xelectron microscopy5.00Y1-133[»]
ProteinModelPortaliP62847.
SMRiP62847. Positions 3-128.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S24e family.Curated

Phylogenomic databases

eggNOGiCOG2004.
GeneTreeiENSGT00390000000153.
HOGENOMiHOG000186306.
HOVERGENiHBG000969.
InParanoidiP62847.
KOiK02974.
OMAiTENREQC.
OrthoDBiEOG7PS1J8.
PhylomeDBiP62847.
TreeFamiTF314134.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
HAMAPiMF_00545. Ribosomal_S24e.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR012678. Ribosomal_L23/L15e_core_dom.
IPR001976. Ribosomal_S24e.
IPR018098. Ribosomal_S24e_CS.
[Graphical view]
PANTHERiPTHR10496. PTHR10496. 1 hit.
PfamiPF01282. Ribosomal_S24e. 1 hit.
[Graphical view]
ProDomiPD006052. Ribosomal_S24e. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF54189. SSF54189. 1 hit.
PROSITEiPS00529. RIBOSOMAL_S24E. 1 hit.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

This entry describes 4 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: P62847-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MNDTVTIRTR KFMTNRLLQR KQMVIDVLHP GKATVPKTEI REKLAKMYKT
60 70 80 90 100
TPDVIFVFGF RTHFGGGKTT GFGMIYDSLD YAKKNEPKHR LARHGLYEKK
110 120 130
KTSRKQRKER KNRMKKVRGT AKANVGAGKK PKE
Length:133
Mass (Da):15,423
Last modified:August 16, 2004 - v1
Checksum:iCE9065C0764D60A6
GO
Isoform 2 (identifier: P62847-2) [UniParc] [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     131-133: Missing.

Show »
Length:130
Mass (Da):15,069
Checksum:iE0764D60A6DD576E
GO
Isoform 3 (identifier: P62847-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     131-133: PKE → KK

Show »
Length:132
Mass (Da):15,325
Checksum:i107190764D60A6DD
GO
Isoform 4 (identifier: P62847-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     131-133: PKE → MRELGLGVQA...PPSCLSGLGH

Note: No experimental confirmation available.

Show »
Length:289
Mass (Da):32,431
Checksum:i611E080AF85103CD
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei131 – 1333Missing in isoform 2. 2 PublicationsVSP_005724
Alternative sequencei131 – 1333PKE → KK in isoform 3. 1 PublicationVSP_039113
Alternative sequencei131 – 1333PKE → MRELGLGVQALGRISQEERC TDVKNSKARESRGVVWQVEV PGPWSVWTCGRLRRGCGKYL QVAVTWRKTENREQCCQACL LERALVRNGAFMSPASPAPA GSPHPVDGDLVLHLPEALSA TLTLSPHIQAINKSFGPFFE IHQESSCFSPPSCLSGLGH in isoform 4. 1 PublicationVSP_045672

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M31520 mRNA. Translation: AAA36588.1.
U12202 Genomic DNA. Translation: AAB08007.1.
U12202 Genomic DNA. Translation: AAB08006.1.
BX336465 mRNA. No translation available.
AK311776 mRNA. Translation: BAG34719.1.
AK311910 mRNA. Translation: BAG34851.1.
BX537975 mRNA. Translation: CAD97939.1.
AL512628 Genomic DNA. Translation: CAI16467.1.
AL512628 Genomic DNA. Translation: CAI16468.1.
CH471083 Genomic DNA. Translation: EAW54623.1.
CH471083 Genomic DNA. Translation: EAW54625.1.
BC000523 mRNA. Translation: AAH00523.1.
BC003149 mRNA. No translation available.
BC071926 mRNA. Translation: AAH71926.1.
CCDSiCCDS44443.1. [P62847-4]
CCDS7355.1.
CCDS7356.1. [P62847-2]
PIRiJC4671.
JH0213.
RefSeqiNP_001017.1. NM_001026.4. [P62847-1]
NP_001135755.1. NM_001142283.1. [P62847-3]
NP_001135757.1. NM_001142285.1. [P62847-4]
NP_148982.1. NM_033022.3. [P62847-2]
UniGeneiHs.280130.

Genome annotation databases

EnsembliENST00000360830; ENSP00000354074; ENSG00000138326. [P62847-2]
ENST00000372360; ENSP00000361435; ENSG00000138326. [P62847-1]
ENST00000440692; ENSP00000414321; ENSG00000138326. [P62847-4]
GeneIDi6229.
KEGGihsa:6229.
UCSCiuc001jzp.3. human.
uc010qlo.2. human. [P62847-3]

Polymorphism databases

DMDMi51338645.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Web resourcesi

Diamond-Blackfan Anemia mutation database

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M31520 mRNA. Translation: AAA36588.1.
U12202 Genomic DNA. Translation: AAB08007.1.
U12202 Genomic DNA. Translation: AAB08006.1.
BX336465 mRNA. No translation available.
AK311776 mRNA. Translation: BAG34719.1.
AK311910 mRNA. Translation: BAG34851.1.
BX537975 mRNA. Translation: CAD97939.1.
AL512628 Genomic DNA. Translation: CAI16467.1.
AL512628 Genomic DNA. Translation: CAI16468.1.
CH471083 Genomic DNA. Translation: EAW54623.1.
CH471083 Genomic DNA. Translation: EAW54625.1.
BC000523 mRNA. Translation: AAH00523.1.
BC003149 mRNA. No translation available.
BC071926 mRNA. Translation: AAH71926.1.
CCDSiCCDS44443.1. [P62847-4]
CCDS7355.1.
CCDS7356.1. [P62847-2]
PIRiJC4671.
JH0213.
RefSeqiNP_001017.1. NM_001026.4. [P62847-1]
NP_001135755.1. NM_001142283.1. [P62847-3]
NP_001135757.1. NM_001142285.1. [P62847-4]
NP_148982.1. NM_033022.3. [P62847-2]
UniGeneiHs.280130.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4V6Xelectron microscopy5.00Y1-133[»]
ProteinModelPortaliP62847.
SMRiP62847. Positions 3-128.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi112143. 145 interactions.
IntActiP62847. 22 interactions.
MINTiMINT-4719640.
STRINGi9606.ENSP00000414321.

PTM databases

PhosphoSiteiP62847.

Polymorphism databases

DMDMi51338645.

Proteomic databases

MaxQBiP62847.
PaxDbiP62847.
PRIDEiP62847.

Protocols and materials databases

DNASUi6229.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000360830; ENSP00000354074; ENSG00000138326. [P62847-2]
ENST00000372360; ENSP00000361435; ENSG00000138326. [P62847-1]
ENST00000440692; ENSP00000414321; ENSG00000138326. [P62847-4]
GeneIDi6229.
KEGGihsa:6229.
UCSCiuc001jzp.3. human.
uc010qlo.2. human. [P62847-3]

Organism-specific databases

CTDi6229.
GeneCardsiGC10P079793.
GeneReviewsiRPS24.
HGNCiHGNC:10411. RPS24.
HPAiHPA003364.
MIMi602412. gene.
610629. phenotype.
neXtProtiNX_P62847.
Orphaneti124. Blackfan-Diamond anemia.
PharmGKBiPA34815.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiCOG2004.
GeneTreeiENSGT00390000000153.
HOGENOMiHOG000186306.
HOVERGENiHBG000969.
InParanoidiP62847.
KOiK02974.
OMAiTENREQC.
OrthoDBiEOG7PS1J8.
PhylomeDBiP62847.
TreeFamiTF314134.

Enzyme and pathway databases

ReactomeiREACT_1079. Formation of the ternary complex, and subsequently, the 43S complex.
REACT_115902. SRP-dependent cotranslational protein targeting to membrane.
REACT_1404. Peptide chain elongation.
REACT_1797. Formation of a pool of free 40S subunits.
REACT_1979. Translation initiation complex formation.
REACT_1986. Eukaryotic Translation Termination.
REACT_2085. GTP hydrolysis and joining of the 60S ribosomal subunit.
REACT_75768. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
REACT_75822. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
REACT_79. L13a-mediated translational silencing of Ceruloplasmin expression.
REACT_931. Ribosomal scanning and start codon recognition.
REACT_9491. Viral mRNA Translation.

Miscellaneous databases

ChiTaRSiRPS24. human.
GeneWikiiRPS24.
GenomeRNAii6229.
NextBioi24179.
PROiP62847.
SOURCEiSearch...

Gene expression databases

BgeeiP62847.
CleanExiHS_RPS24.
ExpressionAtlasiP62847. baseline and differential.
GenevestigatoriP62847.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
HAMAPiMF_00545. Ribosomal_S24e.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR012678. Ribosomal_L23/L15e_core_dom.
IPR001976. Ribosomal_S24e.
IPR018098. Ribosomal_S24e_CS.
[Graphical view]
PANTHERiPTHR10496. PTHR10496. 1 hit.
PfamiPF01282. Ribosomal_S24e. 1 hit.
[Graphical view]
ProDomiPD006052. Ribosomal_S24e. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF54189. SSF54189. 1 hit.
PROSITEiPS00529. RIBOSOMAL_S24E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "A cDNA encoding human ribosomal protein S24."
    Brown S.J., Jewell A., Maki C.G., Roufa D.J.
    Gene 91:293-296(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
  2. "The gene encoding human ribosomal protein S24 and tissue-specific expression of differentially spliced mRNAs."
    Xu W.-B., Roufa D.J.
    Gene 169:257-262(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], ALTERNATIVE SPLICING.
  3. "Full-length cDNA libraries and normalization."
    Li W.B., Gruber C., Jessee J., Polayes D.
    Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4).
    Tissue: Placenta.
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
    Tissue: Brain and Thymus.
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
    Tissue: Retina.
  6. "The DNA sequence and comparative analysis of human chromosome 10."
    Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J.
    , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
    Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Kidney and Muscle.
  9. Quadroni M.
    Submitted (OCT-2004) to UniProtKB
    Cited for: PROTEIN SEQUENCE OF 1-8; 50-61; 69-83 AND 119-132, ACETYLATION AT MET-1, IDENTIFICATION BY MASS SPECTROMETRY.
    Tissue: B-cell lymphoma.
  10. "Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry."
    Vladimirov S.N., Ivanov A.V., Karpova G.G., Musolyamov A.K., Egorov T.A., Thiede B., Wittmann-Liebold B., Otto A.
    Eur. J. Biochem. 239:144-149(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 69-83.
    Tissue: Placenta.
  11. Cited for: INVOLVEMENT IN DBA3, TISSUE SPECIFICITY.
  12. "Mutation of ribosomal protein RPS24 in Diamond-Blackfan anemia results in a ribosome biogenesis disorder."
    Choesmel V., Fribourg S., Aguissa-Toure A.H., Pinaud N., Legrand P., Gazda H.T., Gleizes P.E.
    Hum. Mol. Genet. 17:1253-1263(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  13. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  14. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-9, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  15. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  16. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
    Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T., Giglione C.
    Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  17. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  18. Cited for: STRUCTURE BY ELECTRON MICROSCOPY (5.0 ANGSTROMS) OF 80S RIBOSOME.

Entry informationi

Entry nameiRS24_HUMAN
AccessioniPrimary (citable) accession number: P62847
Secondary accession number(s): E7EPK6
, P16632, Q5T0P7, Q5T0P8, Q7Z3D1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: August 16, 2004
Last modified: February 4, 2015
This is version 122 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. Ribosomal proteins
    Ribosomal proteins families and list of entries
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.