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P62847

- RS24_HUMAN

UniProt

P62847 - RS24_HUMAN

Protein

40S ribosomal protein S24

Gene

RPS24

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.1 Publication

    GO - Molecular functioni

    1. nucleotide binding Source: InterPro
    2. poly(A) RNA binding Source: UniProtKB
    3. structural constituent of ribosome Source: UniProtKB
    4. translation initiation factor binding Source: UniProtKB

    GO - Biological processi

    1. cellular protein metabolic process Source: Reactome
    2. erythrocyte homeostasis Source: UniProtKB
    3. gene expression Source: Reactome
    4. maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: RefGenome
    5. mRNA metabolic process Source: Reactome
    6. nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Source: Reactome
    7. ribosomal small subunit biogenesis Source: UniProtKB
    8. RNA metabolic process Source: Reactome
    9. rRNA processing Source: UniProtKB
    10. SRP-dependent cotranslational protein targeting to membrane Source: Reactome
    11. translation Source: UniProtKB
    12. translational elongation Source: Reactome
    13. translational initiation Source: Reactome
    14. translational termination Source: Reactome
    15. viral life cycle Source: Reactome
    16. viral process Source: Reactome
    17. viral transcription Source: Reactome

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Enzyme and pathway databases

    ReactomeiREACT_1079. Formation of the ternary complex, and subsequently, the 43S complex.
    REACT_115902. SRP-dependent cotranslational protein targeting to membrane.
    REACT_1404. Peptide chain elongation.
    REACT_1797. Formation of a pool of free 40S subunits.
    REACT_1979. Translation initiation complex formation.
    REACT_1986. Eukaryotic Translation Termination.
    REACT_2085. GTP hydrolysis and joining of the 60S ribosomal subunit.
    REACT_75768. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_75822. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
    REACT_79. L13a-mediated translational silencing of Ceruloplasmin expression.
    REACT_931. Ribosomal scanning and start codon recognition.
    REACT_9491. Viral mRNA Translation.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    40S ribosomal protein S24
    Gene namesi
    Name:RPS24
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 10

    Organism-specific databases

    HGNCiHGNC:10411. RPS24.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: HPA
    2. cytosol Source: Reactome
    3. cytosolic small ribosomal subunit Source: UniProtKB
    4. membrane Source: UniProtKB
    5. nucleolus Source: RefGenome
    6. nucleus Source: UniProt
    7. small ribosomal subunit Source: UniProtKB

    Pathology & Biotechi

    Involvement in diseasei

    Diamond-Blackfan anemia 3 (DBA3) [MIM:610629]: A form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of developing leukemia. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies.1 Publication
    Note: The disease is caused by mutations affecting the gene represented in this entry.

    Keywords - Diseasei

    Diamond-Blackfan anemia

    Organism-specific databases

    MIMi610629. phenotype.
    Orphaneti124. Blackfan-Diamond anemia.
    PharmGKBiPA34815.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 13313340S ribosomal protein S24PRO_0000137623Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei1 – 11N-acetylmethionine4 Publications
    Modified residuei9 – 91Phosphothreonine1 Publication

    Keywords - PTMi

    Acetylation, Phosphoprotein

    Proteomic databases

    MaxQBiP62847.
    PaxDbiP62847.
    PRIDEiP62847.

    PTM databases

    PhosphoSiteiP62847.

    Expressioni

    Tissue specificityi

    Mature tissues, such as adult brain, skeletal muscle, heart, and kidney, express low levels, whereas tissues and organs with significant populations of proliferating cells, such as fetal brain, placenta, bone marrow, and various glandular organs, contain significantly higher levels.1 Publication

    Gene expression databases

    ArrayExpressiP62847.
    BgeeiP62847.
    CleanExiHS_RPS24.
    GenevestigatoriP62847.

    Organism-specific databases

    HPAiHPA003364.

    Interactioni

    Protein-protein interaction databases

    BioGridi112143. 142 interactions.
    IntActiP62847. 22 interactions.
    MINTiMINT-4719640.
    STRINGi9606.ENSP00000414321.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3J3Aelectron microscopy5.00Y1-133[»]
    ProteinModelPortaliP62847.
    SMRiP62847. Positions 3-128.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein S24e family.Curated

    Phylogenomic databases

    eggNOGiCOG2004.
    HOGENOMiHOG000186306.
    HOVERGENiHBG000969.
    InParanoidiP62847.
    KOiK02974.
    OMAiTENREQC.
    OrthoDBiEOG7PS1J8.
    PhylomeDBiP62847.
    TreeFamiTF314134.

    Family and domain databases

    Gene3Di3.30.70.330. 1 hit.
    HAMAPiMF_00545. Ribosomal_S24e.
    InterProiIPR012677. Nucleotide-bd_a/b_plait.
    IPR012678. Ribosomal_L23/L15e_core_dom.
    IPR001976. Ribosomal_S24e.
    IPR018098. Ribosomal_S24e_CS.
    [Graphical view]
    PANTHERiPTHR10496. PTHR10496. 1 hit.
    PfamiPF01282. Ribosomal_S24e. 1 hit.
    [Graphical view]
    ProDomiPD006052. Ribosomal_S24e. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF54189. SSF54189. 1 hit.
    PROSITEiPS00529. RIBOSOMAL_S24E. 1 hit.
    [Graphical view]

    Sequences (4)i

    Sequence statusi: Complete.

    This entry describes 4 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: P62847-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MNDTVTIRTR KFMTNRLLQR KQMVIDVLHP GKATVPKTEI REKLAKMYKT    50
    TPDVIFVFGF RTHFGGGKTT GFGMIYDSLD YAKKNEPKHR LARHGLYEKK 100
    KTSRKQRKER KNRMKKVRGT AKANVGAGKK PKE 133
    Length:133
    Mass (Da):15,423
    Last modified:August 16, 2004 - v1
    Checksum:iCE9065C0764D60A6
    GO
    Isoform 2 (identifier: P62847-2) [UniParc] [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         131-133: Missing.

    Show »
    Length:130
    Mass (Da):15,069
    Checksum:iE0764D60A6DD576E
    GO
    Isoform 3 (identifier: P62847-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         131-133: PKE → KK

    Show »
    Length:132
    Mass (Da):15,325
    Checksum:i107190764D60A6DD
    GO
    Isoform 4 (identifier: P62847-4) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         131-133: PKE → MRELGLGVQA...PPSCLSGLGH

    Note: No experimental confirmation available.

    Show »
    Length:289
    Mass (Da):32,431
    Checksum:i611E080AF85103CD
    GO

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei131 – 1333Missing in isoform 2. 2 PublicationsVSP_005724
    Alternative sequencei131 – 1333PKE → KK in isoform 3. 1 PublicationVSP_039113
    Alternative sequencei131 – 1333PKE → MRELGLGVQALGRISQEERC TDVKNSKARESRGVVWQVEV PGPWSVWTCGRLRRGCGKYL QVAVTWRKTENREQCCQACL LERALVRNGAFMSPASPAPA GSPHPVDGDLVLHLPEALSA TLTLSPHIQAINKSFGPFFE IHQESSCFSPPSCLSGLGH in isoform 4. 1 PublicationVSP_045672

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M31520 mRNA. Translation: AAA36588.1.
    U12202 Genomic DNA. Translation: AAB08007.1.
    U12202 Genomic DNA. Translation: AAB08006.1.
    BX336465 mRNA. No translation available.
    AK311776 mRNA. Translation: BAG34719.1.
    AK311910 mRNA. Translation: BAG34851.1.
    BX537975 mRNA. Translation: CAD97939.1.
    AL512628 Genomic DNA. Translation: CAI16467.1.
    AL512628 Genomic DNA. Translation: CAI16468.1.
    CH471083 Genomic DNA. Translation: EAW54623.1.
    CH471083 Genomic DNA. Translation: EAW54625.1.
    BC000523 mRNA. Translation: AAH00523.1.
    BC003149 mRNA. No translation available.
    BC071926 mRNA. Translation: AAH71926.1.
    CCDSiCCDS44443.1. [P62847-4]
    CCDS7355.1.
    CCDS7356.1. [P62847-2]
    PIRiJC4671.
    JH0213.
    RefSeqiNP_001017.1. NM_001026.4. [P62847-1]
    NP_001135755.1. NM_001142283.1. [P62847-3]
    NP_001135757.1. NM_001142285.1. [P62847-4]
    NP_148982.1. NM_033022.3. [P62847-2]
    UniGeneiHs.280130.

    Genome annotation databases

    EnsembliENST00000360830; ENSP00000354074; ENSG00000138326. [P62847-2]
    ENST00000372360; ENSP00000361435; ENSG00000138326. [P62847-1]
    ENST00000440692; ENSP00000414321; ENSG00000138326. [P62847-4]
    GeneIDi6229.
    KEGGihsa:6229.
    UCSCiuc001jzp.3. human.
    uc010qlo.2. human. [P62847-3]

    Polymorphism databases

    DMDMi51338645.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Web resourcesi

    Diamond-Blackfan Anemia mutation database

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M31520 mRNA. Translation: AAA36588.1 .
    U12202 Genomic DNA. Translation: AAB08007.1 .
    U12202 Genomic DNA. Translation: AAB08006.1 .
    BX336465 mRNA. No translation available.
    AK311776 mRNA. Translation: BAG34719.1 .
    AK311910 mRNA. Translation: BAG34851.1 .
    BX537975 mRNA. Translation: CAD97939.1 .
    AL512628 Genomic DNA. Translation: CAI16467.1 .
    AL512628 Genomic DNA. Translation: CAI16468.1 .
    CH471083 Genomic DNA. Translation: EAW54623.1 .
    CH471083 Genomic DNA. Translation: EAW54625.1 .
    BC000523 mRNA. Translation: AAH00523.1 .
    BC003149 mRNA. No translation available.
    BC071926 mRNA. Translation: AAH71926.1 .
    CCDSi CCDS44443.1. [P62847-4 ]
    CCDS7355.1.
    CCDS7356.1. [P62847-2 ]
    PIRi JC4671.
    JH0213.
    RefSeqi NP_001017.1. NM_001026.4. [P62847-1 ]
    NP_001135755.1. NM_001142283.1. [P62847-3 ]
    NP_001135757.1. NM_001142285.1. [P62847-4 ]
    NP_148982.1. NM_033022.3. [P62847-2 ]
    UniGenei Hs.280130.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3J3A electron microscopy 5.00 Y 1-133 [» ]
    ProteinModelPortali P62847.
    SMRi P62847. Positions 3-128.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 112143. 142 interactions.
    IntActi P62847. 22 interactions.
    MINTi MINT-4719640.
    STRINGi 9606.ENSP00000414321.

    PTM databases

    PhosphoSitei P62847.

    Polymorphism databases

    DMDMi 51338645.

    Proteomic databases

    MaxQBi P62847.
    PaxDbi P62847.
    PRIDEi P62847.

    Protocols and materials databases

    DNASUi 6229.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000360830 ; ENSP00000354074 ; ENSG00000138326 . [P62847-2 ]
    ENST00000372360 ; ENSP00000361435 ; ENSG00000138326 . [P62847-1 ]
    ENST00000440692 ; ENSP00000414321 ; ENSG00000138326 . [P62847-4 ]
    GeneIDi 6229.
    KEGGi hsa:6229.
    UCSCi uc001jzp.3. human.
    uc010qlo.2. human. [P62847-3 ]

    Organism-specific databases

    CTDi 6229.
    GeneCardsi GC10P079793.
    GeneReviewsi RPS24.
    HGNCi HGNC:10411. RPS24.
    HPAi HPA003364.
    MIMi 602412. gene.
    610629. phenotype.
    neXtProti NX_P62847.
    Orphaneti 124. Blackfan-Diamond anemia.
    PharmGKBi PA34815.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG2004.
    HOGENOMi HOG000186306.
    HOVERGENi HBG000969.
    InParanoidi P62847.
    KOi K02974.
    OMAi TENREQC.
    OrthoDBi EOG7PS1J8.
    PhylomeDBi P62847.
    TreeFami TF314134.

    Enzyme and pathway databases

    Reactomei REACT_1079. Formation of the ternary complex, and subsequently, the 43S complex.
    REACT_115902. SRP-dependent cotranslational protein targeting to membrane.
    REACT_1404. Peptide chain elongation.
    REACT_1797. Formation of a pool of free 40S subunits.
    REACT_1979. Translation initiation complex formation.
    REACT_1986. Eukaryotic Translation Termination.
    REACT_2085. GTP hydrolysis and joining of the 60S ribosomal subunit.
    REACT_75768. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_75822. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
    REACT_79. L13a-mediated translational silencing of Ceruloplasmin expression.
    REACT_931. Ribosomal scanning and start codon recognition.
    REACT_9491. Viral mRNA Translation.

    Miscellaneous databases

    ChiTaRSi RPS24. human.
    GeneWikii RPS24.
    GenomeRNAii 6229.
    NextBioi 24179.
    PROi P62847.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi P62847.
    Bgeei P62847.
    CleanExi HS_RPS24.
    Genevestigatori P62847.

    Family and domain databases

    Gene3Di 3.30.70.330. 1 hit.
    HAMAPi MF_00545. Ribosomal_S24e.
    InterProi IPR012677. Nucleotide-bd_a/b_plait.
    IPR012678. Ribosomal_L23/L15e_core_dom.
    IPR001976. Ribosomal_S24e.
    IPR018098. Ribosomal_S24e_CS.
    [Graphical view ]
    PANTHERi PTHR10496. PTHR10496. 1 hit.
    Pfami PF01282. Ribosomal_S24e. 1 hit.
    [Graphical view ]
    ProDomi PD006052. Ribosomal_S24e. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF54189. SSF54189. 1 hit.
    PROSITEi PS00529. RIBOSOMAL_S24E. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "A cDNA encoding human ribosomal protein S24."
      Brown S.J., Jewell A., Maki C.G., Roufa D.J.
      Gene 91:293-296(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    2. "The gene encoding human ribosomal protein S24 and tissue-specific expression of differentially spliced mRNAs."
      Xu W.-B., Roufa D.J.
      Gene 169:257-262(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], ALTERNATIVE SPLICING.
    3. "Full-length cDNA libraries and normalization."
      Li W.B., Gruber C., Jessee J., Polayes D.
      Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4).
      Tissue: Placenta.
    4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
      Tissue: Brain and Thymus.
    5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
      Tissue: Retina.
    6. "The DNA sequence and comparative analysis of human chromosome 10."
      Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J.
      , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
      Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
      Tissue: Kidney and Muscle.
    9. Quadroni M.
      Submitted (OCT-2004) to UniProtKB
      Cited for: PROTEIN SEQUENCE OF 1-8; 50-61; 69-83 AND 119-132, ACETYLATION AT MET-1, IDENTIFICATION BY MASS SPECTROMETRY.
      Tissue: B-cell lymphoma.
    10. "Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry."
      Vladimirov S.N., Ivanov A.V., Karpova G.G., Musolyamov A.K., Egorov T.A., Thiede B., Wittmann-Liebold B., Otto A.
      Eur. J. Biochem. 239:144-149(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 69-83.
      Tissue: Placenta.
    11. Cited for: INVOLVEMENT IN DBA3, TISSUE SPECIFICITY.
    12. "Mutation of ribosomal protein RPS24 in Diamond-Blackfan anemia results in a ribosome biogenesis disorder."
      Choesmel V., Fribourg S., Aguissa-Toure A.H., Pinaud N., Legrand P., Gazda H.T., Gleizes P.E.
      Hum. Mol. Genet. 17:1253-1263(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    13. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
      Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    14. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-9, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    15. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    16. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
      Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T., Giglione C.
      Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    17. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    18. Cited for: STRUCTURE BY ELECTRON MICROSCOPY (5.0 ANGSTROMS) OF 80S RIBOSOME.

    Entry informationi

    Entry nameiRS24_HUMAN
    AccessioniPrimary (citable) accession number: P62847
    Secondary accession number(s): E7EPK6
    , P16632, Q5T0P7, Q5T0P8, Q7Z3D1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 16, 2004
    Last sequence update: August 16, 2004
    Last modified: October 1, 2014
    This is version 119 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. Human chromosome 10
      Human chromosome 10: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    4. Ribosomal proteins
      Ribosomal proteins families and list of entries
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3