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Protein

40S ribosomal protein S15

Gene

Rps15

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • RNA binding Source: RGD
  • structural constituent of ribosome Source: RGD

GO - Biological processi

  • liver regeneration Source: RGD
  • osteoblast differentiation Source: RGD
  • ribosomal small subunit assembly Source: RGD
  • ribosomal small subunit biogenesis Source: RGD
  • ribosomal small subunit export from nucleus Source: RGD
  • rRNA processing Source: RGD
  • translation Source: ProtInc

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-RNO-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-RNO-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-RNO-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.
R-RNO-72649. Translation initiation complex formation.
R-RNO-72689. Formation of a pool of free 40S subunits.
R-RNO-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-RNO-72702. Ribosomal scanning and start codon recognition.
R-RNO-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-RNO-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-RNO-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S15
Alternative name(s):
RIG protein
Gene namesi
Name:Rps15
Synonyms:Rig
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 7

Organism-specific databases

RGDi62026. Rps15.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001300322 – 14540S ribosomal protein S15Add BLAST144

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanine1 Publication1
Cross-linki108Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity

Keywords - PTMi

Acetylation, Isopeptide bond, Ubl conjugation

Proteomic databases

PaxDbiP62845.
PRIDEiP62845.

PTM databases

iPTMnetiP62845.
PhosphoSitePlusiP62845.

Expressioni

Gene expression databases

BgeeiENSRNOG00000024603.
GenevisibleiP62845. RN.

Interactioni

Protein-protein interaction databases

IntActiP62845. 1 interactor.
MINTiMINT-1863481.
STRINGi10116.ENSRNOP00000035156.

Structurei

3D structure databases

ProteinModelPortaliP62845.
SMRiP62845.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0898. Eukaryota.
COG0185. LUCA.
GeneTreeiENSGT00390000000475.
HOGENOMiHOG000111561.
HOVERGENiHBG000709.
InParanoidiP62845.
KOiK02958.
OMAiVIRTHCR.
OrthoDBiEOG091G0ZRG.
PhylomeDBiP62845.
TreeFamiTF318650.

Family and domain databases

Gene3Di3.30.860.10. 1 hit.
HAMAPiMF_00531. Ribosomal_S19. 1 hit.
InterProiView protein in InterPro
IPR002222. Ribosomal_S19.
IPR020934. Ribosomal_S19_CS.
IPR023575. Ribosomal_S19_SF.
IPR005713. Ribosomal_S19A/S15e.
PANTHERiPTHR11880. PTHR11880. 1 hit.
PfamiView protein in Pfam
PF00203. Ribosomal_S19. 1 hit.
PIRSFiPIRSF002144. Ribosomal_S19. 1 hit.
PRINTSiPR00975. RIBOSOMALS19.
SUPFAMiSSF54570. SSF54570. 1 hit.
TIGRFAMsiTIGR01025. uS19_arch. 1 hit.
PROSITEiView protein in PROSITE
PS00323. RIBOSOMAL_S19. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P62845-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEVEQKKKR TFRKFTYRGV DLDQLLDMSY EQLMQLYSAR QRRRLNRGLR
60 70 80 90 100
RKQHSLLKRL RKAKKEAPPM EKPEVVKTHL RDMIILPEMV GSMVGVYNGK
110 120 130 140
TFNQVEIKPE MIGHYLGEFS ITYKPVKHGR PGIGATHSSR FIPLK
Length:145
Mass (Da):17,040
Last modified:January 23, 2007 - v2
Checksum:iCA2C682302C7B387
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M19393 mRNA. Translation: AAA42044.1.
D11388 Genomic DNA. Translation: BAA01984.1.
PIRiS28939. R3RT15.
RefSeqiNP_058847.1. NM_017151.2.
UniGeneiRn.3391.

Genome annotation databases

EnsembliENSRNOT00000029791; ENSRNOP00000035156; ENSRNOG00000024603.
GeneIDi29285.
KEGGirno:29285.
UCSCiRGD:62026. rat.

Similar proteinsi

Entry informationi

Entry nameiRS15_RAT
AccessioniPrimary (citable) accession number: P62845
Secondary accession number(s): P11174
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: January 23, 2007
Last modified: November 22, 2017
This is version 101 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families