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Protein

40S ribosomal protein S15

Gene

Rps15

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • RNA binding Source: ProtInc
  • structural constituent of ribosome Source: RGD

GO - Biological processi

  • ribosomal small subunit assembly Source: RGD
  • translation Source: ProtInc
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-RNO-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-RNO-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-RNO-72649. Translation initiation complex formation.
R-RNO-72689. Formation of a pool of free 40S subunits.
R-RNO-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-RNO-72702. Ribosomal scanning and start codon recognition.
R-RNO-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-RNO-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-RNO-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S15
Alternative name(s):
RIG protein
Gene namesi
Name:Rps15
Synonyms:Rig
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 7

Organism-specific databases

RGDi62026. Rps15.

Subcellular locationi

GO - Cellular componenti

  • cytosolic small ribosomal subunit Source: RGD
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemoved1 Publication
Chaini2 – 14514440S ribosomal protein S15PRO_0000130032Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanine1 Publication

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiP62845.
PRIDEiP62845.

PTM databases

iPTMnetiP62845.

Expressioni

Gene expression databases

GenevisibleiP62845. RN.

Interactioni

Protein-protein interaction databases

IntActiP62845. 1 interaction.
MINTiMINT-1863481.
STRINGi10116.ENSRNOP00000035156.

Structurei

3D structure databases

ProteinModelPortaliP62845.
SMRiP62845. Positions 15-134.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S19P family.Curated

Phylogenomic databases

eggNOGiKOG0898. Eukaryota.
COG0185. LUCA.
GeneTreeiENSGT00390000000475.
HOGENOMiHOG000111561.
HOVERGENiHBG000709.
InParanoidiP62845.
KOiK02958.
OMAiPIRTHSR.
OrthoDBiEOG780RPS.
PhylomeDBiP62845.
TreeFamiTF318650.

Family and domain databases

Gene3Di3.30.860.10. 1 hit.
HAMAPiMF_00531. Ribosomal_S19.
InterProiIPR002222. Ribosomal_S19.
IPR020934. Ribosomal_S19_CS.
IPR023575. Ribosomal_S19_SF.
IPR005713. Ribosomal_S19A/S15e.
[Graphical view]
PANTHERiPTHR11880. PTHR11880. 1 hit.
PfamiPF00203. Ribosomal_S19. 1 hit.
[Graphical view]
PIRSFiPIRSF002144. Ribosomal_S19. 1 hit.
PRINTSiPR00975. RIBOSOMALS19.
SUPFAMiSSF54570. SSF54570. 1 hit.
TIGRFAMsiTIGR01025. uS19_arch. 1 hit.
PROSITEiPS00323. RIBOSOMAL_S19. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P62845-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEVEQKKKR TFRKFTYRGV DLDQLLDMSY EQLMQLYSAR QRRRLNRGLR
60 70 80 90 100
RKQHSLLKRL RKAKKEAPPM EKPEVVKTHL RDMIILPEMV GSMVGVYNGK
110 120 130 140
TFNQVEIKPE MIGHYLGEFS ITYKPVKHGR PGIGATHSSR FIPLK
Length:145
Mass (Da):17,040
Last modified:January 23, 2007 - v2
Checksum:iCA2C682302C7B387
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M19393 mRNA. Translation: AAA42044.1.
D11388 Genomic DNA. Translation: BAA01984.1.
PIRiS28939. R3RT15.
RefSeqiNP_058847.1. NM_017151.2.
UniGeneiRn.3391.

Genome annotation databases

EnsembliENSRNOT00000029791; ENSRNOP00000035156; ENSRNOG00000024603.
GeneIDi29285.
KEGGirno:29285.
UCSCiRGD:62026. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M19393 mRNA. Translation: AAA42044.1.
D11388 Genomic DNA. Translation: BAA01984.1.
PIRiS28939. R3RT15.
RefSeqiNP_058847.1. NM_017151.2.
UniGeneiRn.3391.

3D structure databases

ProteinModelPortaliP62845.
SMRiP62845. Positions 15-134.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP62845. 1 interaction.
MINTiMINT-1863481.
STRINGi10116.ENSRNOP00000035156.

PTM databases

iPTMnetiP62845.

Proteomic databases

PaxDbiP62845.
PRIDEiP62845.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000029791; ENSRNOP00000035156; ENSRNOG00000024603.
GeneIDi29285.
KEGGirno:29285.
UCSCiRGD:62026. rat.

Organism-specific databases

CTDi6209.
RGDi62026. Rps15.

Phylogenomic databases

eggNOGiKOG0898. Eukaryota.
COG0185. LUCA.
GeneTreeiENSGT00390000000475.
HOGENOMiHOG000111561.
HOVERGENiHBG000709.
InParanoidiP62845.
KOiK02958.
OMAiPIRTHSR.
OrthoDBiEOG780RPS.
PhylomeDBiP62845.
TreeFamiTF318650.

Enzyme and pathway databases

ReactomeiR-RNO-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-RNO-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-RNO-72649. Translation initiation complex formation.
R-RNO-72689. Formation of a pool of free 40S subunits.
R-RNO-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-RNO-72702. Ribosomal scanning and start codon recognition.
R-RNO-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-RNO-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-RNO-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

NextBioi608669.
PROiP62845.

Gene expression databases

GenevisibleiP62845. RN.

Family and domain databases

Gene3Di3.30.860.10. 1 hit.
HAMAPiMF_00531. Ribosomal_S19.
InterProiIPR002222. Ribosomal_S19.
IPR020934. Ribosomal_S19_CS.
IPR023575. Ribosomal_S19_SF.
IPR005713. Ribosomal_S19A/S15e.
[Graphical view]
PANTHERiPTHR11880. PTHR11880. 1 hit.
PfamiPF00203. Ribosomal_S19. 1 hit.
[Graphical view]
PIRSFiPIRSF002144. Ribosomal_S19. 1 hit.
PRINTSiPR00975. RIBOSOMALS19.
SUPFAMiSSF54570. SSF54570. 1 hit.
TIGRFAMsiTIGR01025. uS19_arch. 1 hit.
PROSITEiPS00323. RIBOSOMAL_S19. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "The primary structure of rat rig/ribosomal protein S15 gene."
    Takasawa S., Tohgo A., Unno M., Shiga K., Yonekura H., Okamoto H.
    Biochim. Biophys. Acta 1132:228-230(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  3. "Rig encodes ribosomal protein S15. The primary structure of mammalian ribosomal protein S15."
    Kitagawa M., Takasawa S., Kikuchi N., Itoh T., Teraoka H., Yamamoto H., Okamoto H.
    FEBS Lett. 283:210-214(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 2-145, CLEAVAGE OF INITIATOR METHIONINE, ACETYLATION AT ALA-2.
    Strain: Wistar.
    Tissue: Liver.

Entry informationi

Entry nameiRS15_RAT
AccessioniPrimary (citable) accession number: P62845
Secondary accession number(s): P11174
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: January 23, 2007
Last modified: February 17, 2016
This is version 88 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.