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P62843

- RS15_MOUSE

UniProt

P62843 - RS15_MOUSE

Protein

40S ribosomal protein S15

Gene

Rps15

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. protein binding Source: MGI
    2. RNA binding Source: InterPro
    3. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. translation Source: InterPro

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Enzyme and pathway databases

    ReactomeiREACT_196445. SRP-dependent cotranslational protein targeting to membrane.
    REACT_198524. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_198528. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    40S ribosomal protein S15
    Alternative name(s):
    RIG protein
    Gene namesi
    Name:Rps15
    Synonyms:Rig
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 10

    Organism-specific databases

    MGIiMGI:98117. Rps15.

    Subcellular locationi

    GO - Cellular componenti

    1. small ribosomal subunit Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11RemovedBy similarity
    Chaini2 – 14514440S ribosomal protein S15PRO_0000130029Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei2 – 21N-acetylalanineBy similarity

    Keywords - PTMi

    Acetylation

    Proteomic databases

    MaxQBiP62843.
    PaxDbiP62843.
    PRIDEiP62843.

    PTM databases

    PhosphoSiteiP62843.

    Expressioni

    Gene expression databases

    ArrayExpressiP62843.
    BgeeiP62843.
    CleanExiMM_RPS15.
    GenevestigatoriP62843.

    Interactioni

    Protein-protein interaction databases

    BioGridi203003. 1 interaction.
    IntActiP62843. 7 interactions.
    MINTiMINT-1213111.

    Structurei

    3D structure databases

    ProteinModelPortaliP62843.
    SMRiP62843. Positions 4-130.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein S19P family.Curated

    Phylogenomic databases

    eggNOGiCOG0185.
    GeneTreeiENSGT00390000000475.
    HOGENOMiHOG000111561.
    HOVERGENiHBG000709.
    InParanoidiP62843.
    KOiK02958.
    OMAiYCARQRR.
    OrthoDBiEOG780RPS.
    PhylomeDBiP62843.
    TreeFamiTF318650.

    Family and domain databases

    Gene3Di3.30.860.10. 1 hit.
    HAMAPiMF_00531. Ribosomal_S19.
    InterProiIPR002222. Ribosomal_S19.
    IPR020934. Ribosomal_S19_CS.
    IPR023575. Ribosomal_S19_SF.
    IPR005713. Ribosomal_S19A/S15e.
    [Graphical view]
    PANTHERiPTHR11880. PTHR11880. 1 hit.
    PfamiPF00203. Ribosomal_S19. 1 hit.
    [Graphical view]
    PIRSFiPIRSF002144. Ribosomal_S19. 1 hit.
    PRINTSiPR00975. RIBOSOMALS19.
    SUPFAMiSSF54570. SSF54570. 1 hit.
    TIGRFAMsiTIGR01025. rpsS_arch. 1 hit.
    PROSITEiPS00323. RIBOSOMAL_S19. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P62843-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAEVEQKKKR TFRKFTYRGV DLDQLLDMSY EQLMQLYSAR QRRRLNRGLR    50
    RKQHSLLKRL RKAKKEAPPM EKPEVVKTHL RDMIILPEMV GSMVGVYNGK 100
    TFNQVEIKPE MIGHYLGEFS ITYKPVKHGR PGIGATHSSR FIPLK 145
    Length:145
    Mass (Da):17,040
    Last modified:January 23, 2007 - v2
    Checksum:iCA2C682302C7B387
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M33330 mRNA. Translation: AAA40055.1.
    BC010763 mRNA. Translation: AAH10763.1.
    BC094409 mRNA. Translation: AAH94409.1.
    CCDSiCCDS35978.1.
    PIRiA34823.
    RefSeqiNP_033117.1. NM_009091.2.
    UniGeneiMm.643.

    Genome annotation databases

    EnsembliENSMUST00000068408; ENSMUSP00000069004; ENSMUSG00000063457.
    GeneIDi20054.
    KEGGimmu:20054.
    UCSCiuc007gcn.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M33330 mRNA. Translation: AAA40055.1 .
    BC010763 mRNA. Translation: AAH10763.1 .
    BC094409 mRNA. Translation: AAH94409.1 .
    CCDSi CCDS35978.1.
    PIRi A34823.
    RefSeqi NP_033117.1. NM_009091.2.
    UniGenei Mm.643.

    3D structure databases

    ProteinModelPortali P62843.
    SMRi P62843. Positions 4-130.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 203003. 1 interaction.
    IntActi P62843. 7 interactions.
    MINTi MINT-1213111.

    PTM databases

    PhosphoSitei P62843.

    Proteomic databases

    MaxQBi P62843.
    PaxDbi P62843.
    PRIDEi P62843.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000068408 ; ENSMUSP00000069004 ; ENSMUSG00000063457 .
    GeneIDi 20054.
    KEGGi mmu:20054.
    UCSCi uc007gcn.2. mouse.

    Organism-specific databases

    CTDi 6209.
    MGIi MGI:98117. Rps15.

    Phylogenomic databases

    eggNOGi COG0185.
    GeneTreei ENSGT00390000000475.
    HOGENOMi HOG000111561.
    HOVERGENi HBG000709.
    InParanoidi P62843.
    KOi K02958.
    OMAi YCARQRR.
    OrthoDBi EOG780RPS.
    PhylomeDBi P62843.
    TreeFami TF318650.

    Enzyme and pathway databases

    Reactomei REACT_196445. SRP-dependent cotranslational protein targeting to membrane.
    REACT_198524. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_198528. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

    Miscellaneous databases

    NextBioi 297563.
    PROi P62843.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi P62843.
    Bgeei P62843.
    CleanExi MM_RPS15.
    Genevestigatori P62843.

    Family and domain databases

    Gene3Di 3.30.860.10. 1 hit.
    HAMAPi MF_00531. Ribosomal_S19.
    InterProi IPR002222. Ribosomal_S19.
    IPR020934. Ribosomal_S19_CS.
    IPR023575. Ribosomal_S19_SF.
    IPR005713. Ribosomal_S19A/S15e.
    [Graphical view ]
    PANTHERi PTHR11880. PTHR11880. 1 hit.
    Pfami PF00203. Ribosomal_S19. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF002144. Ribosomal_S19. 1 hit.
    PRINTSi PR00975. RIBOSOMALS19.
    SUPFAMi SSF54570. SSF54570. 1 hit.
    TIGRFAMsi TIGR01025. rpsS_arch. 1 hit.
    PROSITEi PS00323. RIBOSOMAL_S19. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Nucleotide sequence determination of mouse, chicken and Xenopus laevis rig cDNAs: the rig-encoded protein is extremely conserved during vertebrate evolution."
      Sugawara A., Nata K., Inoue C., Takasawa S., Yamamoto H., Okamoto H.
      Biochem. Biophys. Res. Commun. 166:1501-1507(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J and FVB/N.
      Tissue: Kidney and Mammary gland.

    Entry informationi

    Entry nameiRS15_MOUSE
    AccessioniPrimary (citable) accession number: P62843
    Secondary accession number(s): P11174, Q52KC9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 16, 2004
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 83 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3