P62841 (RS15_HUMAN) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 83.
History...
Names·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: 40S ribosomal protein S15 Alternative name(s): RIG protein | ||||
| Gene names |
| ||||
| Organism | Homo sapiens (Human) | ||||
| Taxonomic identifier | 9606 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Protein attributes
| Sequence length | 145 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Sequence similarities | Belongs to the ribosomal protein S19P family. |
Ontologies
Binary interactions
With | Entry | #Exp. | IntAct | Notes |
|---|---|---|---|---|
| UPF2 | Q9HAU5 | 1 | EBI-372635,EBI-372073 |
Sequence annotation (Features)
Sequences
| ||||||||||||||||||
References
| « Hide 'large scale' references | |
| [1] | "Evolutionary conservation of the insulinoma gene rig and its possible function." Inoue C., Shiga K., Takasawa S., Kitagawa M., Yamamoto H., Okamoto H. Proc. Natl. Acad. Sci. U.S.A. 84:6659-6662(1987) [PubMed: 2821540] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. |
| [2] | "Isolation and characterization of the human homologue of rig and its pseudogenes: the functional gene has features characteristic of housekeeping genes." Shiga K., Yamamoto H., Okamoto H. Proc. Natl. Acad. Sci. U.S.A. 87:3594-3598(1990) [PubMed: 2159154] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| [3] | "Cloning and characterization of human insulinoma protein." Yu L., Zhao S.Y. Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. |
| [4] | "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Pancreas. |
| [5] | "Progressive spastic myelopathy in a patient co-infected with HIV-1 and HTLV-II: autoantibodies to the human homologue of rig in blood and cerebrospinal fluid." Rosenblatt J.D., Tomkins P., Rosenthal M., Kacena A., Chan G., Valderama R., Harrington W. Jr., Saxton E., Diagne A., Zhao J.-Q., Mitsuyasu R.T., Weisbart R.H. AIDS 6:1151-1158(1992) [PubMed: 1466847] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 11-145. Tissue: Brain. |
| [6] | "Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry." Vladimirov S.N., Ivanov A.V., Karpova G.G., Musolyamov A.K., Egorov T.A., Thiede B., Wittmann-Liebold B., Otto A. Eur. J. Biochem. 239:144-149(1996) [PubMed: 8706699] [Abstract] Cited for: PROTEIN SEQUENCE OF 101-116. Tissue: Placenta. |
| [7] | "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach." Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S. Anal. Chem. 81:4493-4501(2009) [PubMed: 19413330] [Abstract] Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, MASS SPECTROMETRY. Tissue: Embryonic kidney. |
| [8] | "Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed: 21269460] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EMBL GenBank DDBJ | J02984 mRNA. Translation: AAA36036.1. M32405 Genomic DNA. Translation: AAA36568.1. AF145025 mRNA. Translation: AAP97277.1. BC064908 mRNA. Translation: AAH64908.1. BC105810 mRNA. Translation: AAI05811.1. BC141832 mRNA. Translation: AAI41833.1. | ||||||||||||
| IPI | IPI00479058. | ||||||||||||
| PIR | R3HU15. A35908. | ||||||||||||
| RefSeq | NP_001009.1. NM_001018.3. | ||||||||||||
| UniGene | Hs.406683. | ||||||||||||
3D structure databases | |||||||||||||
| PDBe RCSB PDB PDBj |
| ||||||||||||
| ProteinModelPortal | P62841. | ||||||||||||
| SMR | P62841. Positions 43-130. | ||||||||||||
| ModBase | Search... | ||||||||||||
Protein-protein interaction databases | |||||||||||||
| IntAct | P62841. 5 interactions. | ||||||||||||
| STRING | P62841. | ||||||||||||
PTM databases | |||||||||||||
| PhosphoSite | P62841. | ||||||||||||
Polymorphism databases | |||||||||||||
| DMDM | 51338641. | ||||||||||||
Proteomic databases | |||||||||||||
| PRIDE | P62841. | ||||||||||||
Protocols and materials databases | |||||||||||||
| StructuralBiologyKnowledgebase | Search... | ||||||||||||
Genome annotation databases | |||||||||||||
| Ensembl | ENST00000233609; ENSP00000233609; ENSG00000115268. | ||||||||||||
| GeneID | 6209. | ||||||||||||
| KEGG | hsa:6209. | ||||||||||||
| UCSC | uc002lsp.1. human. | ||||||||||||
Organism-specific databases | |||||||||||||
| CTD | 6209. | ||||||||||||
| GeneCards | GC19P001438. | ||||||||||||
| H-InvDB | HIX0202917. | ||||||||||||
| HGNC | HGNC:10388. RPS15. | ||||||||||||
| MIM | 180535. gene. | ||||||||||||
| neXtProt | NX_P62841. | ||||||||||||
| PharmGKB | PA34787. | ||||||||||||
| GenAtlas | Search... | ||||||||||||
Phylogenomic databases | |||||||||||||
| eggNOG | prNOG20926. | ||||||||||||
| GeneTree | ENSGT00390000000475. | ||||||||||||
| HOGENOM | HBG307515. | ||||||||||||
| HOVERGEN | HBG000709. | ||||||||||||
| InParanoid | P62841. | ||||||||||||
| OMA | THCRDMI. | ||||||||||||
| OrthoDB | EOG45MN6X. | ||||||||||||
| PhylomeDB | P62841. | ||||||||||||
Enzyme and pathway databases | |||||||||||||
| Reactome | REACT_111045. Developmental Biology. REACT_111217. Metabolism. REACT_15380. Diabetes pathways. REACT_17015. Metabolism of proteins. REACT_1762. 3' -UTR-mediated translational regulation. REACT_6167. Influenza Infection. REACT_71. Gene Expression. | ||||||||||||
Gene expression databases | |||||||||||||
| Bgee | P62841. | ||||||||||||
| CleanEx | HS_RPS15. | ||||||||||||
| Genevestigator | P62841. | ||||||||||||
| GermOnline | ENSG00000115268. Homo sapiens. | ||||||||||||
Family and domain databases | |||||||||||||
| InterPro | IPR002222. Ribosomal_S19. IPR020934. Ribosomal_S19_CS. IPR023575. Ribosomal_S19_SF. IPR005713. Ribosomal_S19A/S15e. [Graphical view] | ||||||||||||
| Gene3D | G3DSA:3.30.860.10. Ribosomal_S19. 1 hit. | ||||||||||||
| KO | K02958. | ||||||||||||
| PANTHER | PTHR11880. Ribosomal_S19. 1 hit. | ||||||||||||
| Pfam | PF00203. Ribosomal_S19. 1 hit. [Graphical view] | ||||||||||||
| PIRSF | PIRSF002144. Ribosomal_S19. 1 hit. | ||||||||||||
| PRINTS | PR00975. RIBOSOMALS19. | ||||||||||||
| SUPFAM | SSF54570. Ribosomal_S19. 1 hit. | ||||||||||||
| TIGRFAMs | TIGR01025. RpsS_arch. 1 hit. | ||||||||||||
| PROSITE | PS00323. RIBOSOMAL_S19. 1 hit. [Graphical view] | ||||||||||||
| ProtoNet | Search... | ||||||||||||
Other | |||||||||||||
| NextBio | 24119. | ||||||||||||
| PMAP-CutDB | P62841. | ||||||||||||
| SOURCE | Search... | ||||||||||||
Entry information
| Entry name | RS15_HUMAN | ||||||||
| Accession | Primary (citable) accession number: P62841 Secondary accession number(s): A5D8V9 Q9UDC2 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Chordata Protein Annotation Program | ||||||||
| Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. | ||||||||
Relevant documents
| Ribosomal proteins Ribosomal proteins families and list of entries |
| Human chromosome 19 Human chromosome 19: entries, gene names and cross-references to MIM |
| MIM cross-references Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot |
| PDB cross-references Index of Protein Data Bank (PDB) cross-references |
| SIMILARITY comments Index of protein domains and families |

Clusters with