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Reviewed, UniProtKB/Swiss-Prot P62841 (RS15_HUMAN)

Last modified November 25, 2008. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    40S ribosomal protein S15
Alternative name(s):
    RIG protein
Gene names
Name: RPS15
Synonyms: RIG
OrganismHomo sapiens (Human)
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length145 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level.

General annotation (Comments)

Sequence similarities

Belongs to the ribosomal protein S19P family.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

UPF2Q9HAU51EBI-372635,EBI-372073

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 14514440S ribosomal protein S15
PRO_0000130027

Amino acid modifications

Modified residue21N-acetylalanine By similarity

Sequences

Sequence LengthMass (Da)Tools
P62841-1 [UniParc].

Last modified January 23, 2007. Version 2.
Checksum: CA2C682302C7B387

FASTA14517,040
        10         20         30         40         50         60 
MAEVEQKKKR TFRKFTYRGV DLDQLLDMSY EQLMQLYSAR QRRRLNRGLR RKQHSLLKRL 

        70         80         90        100        110        120 
RKAKKEAPPM EKPEVVKTHL RDMIILPEMV GSMVGVYNGK TFNQVEIKPE MIGHYLGEFS 

       130        140 
ITYKPVKHGR PGIGATHSSR FIPLK 

« Hide

References

« Hide 'large scale' references
[1]"Evolutionary conservation of the insulinoma gene rig and its possible function."
Inoue C., Shiga K., Takasawa S., Kitagawa M., Yamamoto H., Okamoto H.
Proc. Natl. Acad. Sci. U.S.A. 84:6659-6662(1987) [PubMed: 2821540] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"Isolation and characterization of the human homologue of rig and its pseudogenes: the functional gene has features characteristic of housekeeping genes."
Shiga K., Yamamoto H., Okamoto H.
Proc. Natl. Acad. Sci. U.S.A. 87:3594-3598(1990) [PubMed: 2159154] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]"Cloning and characterization of human insulinoma protein."
Yu L., Zhao S.Y.
Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[4]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Pancreas.
[5]"Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry."
Vladimirov S.N., Ivanov A.V., Karpova G.G., Musolyamov A.K., Egorov T.A., Thiede B., Wittmann-Liebold B., Otto A.
Eur. J. Biochem. 239:144-149(1996) [PubMed: 8706699] [Abstract]
Cited for: PROTEIN SEQUENCE OF 101-116.
Tissue: Placenta.

Cross-references

Sequence databases

J02984 mRNA. Translation: AAA36036.1.
M32405 Genomic DNA. Translation: AAA36568.1.
AF145025 mRNA. Translation: AAP97277.1.
BC064908 mRNA. Translation: AAH64908.1.
BC105810 mRNA. Translation: AAI05811.1.
PIRR3HU15. A35908.
RefSeqNP_001009.1.
UniGeneHs.406683

3D structure databases

HSSPHSSP built from PDB template 1QKF based on UniProtKB P80381.
ModBaseSearch...

Protein-protein interaction databases

IntActP62841.

PTM databases

PhosphoSiteP62841.

Genome annotation databases

EnsemblENSG00000115268. Homo sapiens. [Contig view]
GeneID6209.
KEGGhsa:6209.

Organism-specific databases

H-InvDBHIX0040116.
HGNCHGNC:10388. RPS15.
MIM180535. gene.
PharmGKBPA30999.
GenAtlasSearch...
GeneCardsSearch...

Phylogenomic databases

HOGENOMP62841.
HOVERGENP62841.

Enzyme and pathway databases

ReactomeREACT_1762. 3' -UTR-mediated translational regulation.
REACT_6167. Influenza Infection.
REACT_71. Gene Expression.

Gene expression databases

CleanExHS_RPS15.
GermOnlineENSG00000115268. Homo sapiens.

Family and domain databases

InterProIPR005713. Ribosomal_S15_euk/arc.
IPR002222. Ribosomal_S19.
[Graphical view]
Gene3DG3DSA:3.30.860.10. Ribosomal_S19. 1 hit.
PANTHERPTHR11880:SF2. Ribosomal_S15e/a. 1 hit.
PTHR11880. Ribosomal_S19. 1 hit.
PfamPF00203. Ribosomal_S19. 1 hit.
[Graphical view]
PIRSFPIRSF002144. Ribosomal_S19. 1 hit.
PRINTSPR00975. RIBOSOMALS19.
ProDomPD001012. Ribosomal_S19. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsTIGR01025. rpsS_arch. 1 hit.
PROSITEPS00323. RIBOSOMAL_S19. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio24119.
SOURCESearch...

Entry information

Entry nameRS15_HUMAN
AccessionPrimary (citable) accession number: P62841
Secondary accession number(s): P11174, Q3KRA1
Entry history
Integrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: January 23, 2007
Last modified: November 25, 2008
This is version 47 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHPI (Human Proteome Initiative)

Relevant documents

Human chromosome 19

Human chromosome 19: entries, gene names and cross-references to MIM

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Ribosomal proteins

Ribosomal proteins families and list of entries

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents