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P62702 (RS4X_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
40S ribosomal protein S4, X isoform
Gene names
Name:Rps4x
Synonyms:Rps4
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length263 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subunit structure

Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs By similarity.

Subcellular location

Cytoplasm By similarity. Note: Localized in cytoplasmic mRNP granules containing untranslated mRNAs By similarity. HAMAP-Rule MF_00485

Sequence similarities

Belongs to the ribosomal protein S4e family.

Contains 1 S4 RNA-binding domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 26326240S ribosomal protein S4, X isoform HAMAP-Rule MF_00485
PRO_0000130809

Regions

Domain42 – 10463S4 RNA-binding

Experimental info

Sequence conflict91L → M in BAB29207. Ref.2

Sequences

Sequence LengthMass (Da)Tools
P62702 [UniParc].

Last modified January 23, 2007. Version 2.
Checksum: 87200E545A8958B0

FASTA26329,598
        10         20         30         40         50         60 
MARGPKKHLK RVAAPKHWML DKLTGVFAPR PSTGPHKLRE CLPLIIFLRN RLKYALTGDE 

        70         80         90        100        110        120 
VKKICMQRFI KIDGKVRTDI TYPAGFMDVI SIDKTGENFR LIYDTKGRFA VHRITPEEAK 

       130        140        150        160        170        180 
YKLCKVRKIF VGTKGIPHLV THDARTIRYP DPLIKVNDTI QIDLETGKIT DFIKFDTGNL 

       190        200        210        220        230        240 
CMVTGGANLG RIGVITNRER HPGSFDVVHV KDANGNSFAT RLSNIFVIGK GNKPWISLPR 

       250        260 
GKGIRLTIAE ERDKRLAAKQ SSG 

« Hide

References

« Hide 'large scale' references
[1]"Inactivation of the Rps4 gene on the mouse X chromosome."
Zinn A.R., Bressler S.L., Beer-Romero P., Adler D.A., Chapman V.M., Page D.C., Disteche C.M.
Genomics 11:1097-1101(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Head.
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Mammary gland.
[4]"Rps4 maps near the inactivation center on the mouse X chromosome."
Hamvas R.M., Zinn A.R., Keer J.T., Fisher E.M., Beer-Romero P., Brown S.D., Page D.C.
Genomics 12:363-367(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 219-237.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M73436 mRNA. Translation: AAA40075.1.
AK014210 mRNA. Translation: BAB29207.1.
BC009100 mRNA. Translation: AAH09100.1.
M77296 Genomic DNA. Translation: AAA40072.1.
RefSeqNP_033120.1. NM_009094.1.
UniGeneMm.66.

3D structure databases

ProteinModelPortalP62702.
SMRP62702. Positions 1-263.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid203011. 2 interactions.
IntActP62702. 8 interactions.
MINTMINT-1845743.

PTM databases

PhosphoSiteP62702.

Proteomic databases

PaxDbP62702.
PRIDEP62702.

Protocols and materials databases

DNASU20102.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000033683; ENSMUSP00000033683; ENSMUSG00000031320.
GeneID20102.
KEGGmmu:20102.
UCSCuc009tyl.1. mouse.

Organism-specific databases

CTD6191.
MGIMGI:98158. Rps4x.

Phylogenomic databases

eggNOGCOG1471.
HOVERGENHBG000935.
InParanoidP62702.
KOK02987.
OMAGHIQLNL.
OrthoDBEOG77WWD1.
PhylomeDBP62702.
TreeFamTF300612.

Gene expression databases

BgeeP62702.
CleanExMM_RPS4X.
GenevestigatorP62702.

Family and domain databases

HAMAPMF_00485. Ribosomal_S4e.
InterProIPR005824. KOW.
IPR000876. Ribosomal_S4e.
IPR013845. Ribosomal_S4e_central_region.
IPR013843. Ribosomal_S4e_N.
IPR018199. Ribosomal_S4e_N_CS.
IPR002942. S4_RNA-bd.
[Graphical view]
PANTHERPTHR11581. PTHR11581. 1 hit.
PfamPF00467. KOW. 1 hit.
PF00900. Ribosomal_S4e. 1 hit.
PF08071. RS4NT. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
PIRSFPIRSF002116. Ribosomal_S4. 1 hit.
ProDomPD002667. Ribosomal_S4e_central. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTSM00363. S4. 1 hit.
[Graphical view]
PROSITEPS00528. RIBOSOMAL_S4E. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSRPS4X. mouse.
NextBio297599.
PROP62702.
SOURCESearch...

Entry information

Entry nameRS4X_MOUSE
AccessionPrimary (citable) accession number: P62702
Secondary accession number(s): P12631 expand/collapse secondary AC list , P12750, P27576, P55831, Q14727, Q9CXN0
Entry history
Integrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: January 23, 2007
Last modified: April 16, 2014
This is version 88 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot