P62699 (YPEL5_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein yippee-like 5

Gene names

Name:	YPEL5
ORF Names:	CGI-127

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	121 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the yippee family.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 121	121	Protein yippee-like 5		PRO_0000212396

Sequences

	Sequence		Length	Mass (Da)
	P62699 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: ADCF8C4C3B154EAB	FASTA	121	13,842
	10 20 30 40 50 60 MGRIFLDHIG GTRLFSCANC DTILTNRSEL ISTRFTGATG RAFLFNKVVN LQYSEVQDRV 70 80 90 100 110 120 MLTGRHMVRD VSCKNCNSKL GWIYEFATED SQRYKEGRVI LERALVRESE GFEEHVPSDN S

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species." Hosono K., Sasaki T., Minoshima S., Shimizu N. Gene 340:31-43(2004) [PubMed: 15556292] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics." Lai C.-H., Chou C.-Y., Ch'ang L.-Y., Liu C.-S., Lin W.-C. Genome Res. 10:703-713(2000) [PubMed: 10810093] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[3]	"Isolating a new human cDNA." Luo W.Q., Chen J.H., Hu S.N., Zhou Y., Huang X.W., Zhou H.J., Yuan J.G., Qiang B.Q. Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[4]	"Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H. , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K. Nature 434:724-731(2005) [PubMed: 15815621] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[6]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Cervix.
[7]	"The Drosophila gene Yippee reveals a novel family of putative zinc binding proteins highly conserved among eukaryotes." Roxstroem-Lindquist K., Faye I. Insect Mol. Biol. 10:77-86(2001) [PubMed: 11240639] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-101. Tissue: Intestine.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB098739 mRNA. Translation: BAD51380.1. AF151885 mRNA. Translation: AAD34122.1. AF135161 mRNA. Translation: AAF43785.1. AC016907 Genomic DNA. Translation: AAY14780.1. CH471053 Genomic DNA. Translation: EAX00500.1. CH471053 Genomic DNA. Translation: EAX00501.1. CH471053 Genomic DNA. Translation: EAX00504.1. CH471053 Genomic DNA. Translation: EAX00505.1. BC000836 mRNA. Translation: AAH00836.1. BC047237 mRNA. Translation: AAH47237.1. AF172940 mRNA. Translation: AAD47882.1.
IPI	IPI00429538.
PIR	T50836.
RefSeq	NP_001120871.1. NM_001127399.1. NP_001120872.1. NM_001127400.1. NP_001120873.1. NM_001127401.1. NP_057145.1. NM_016061.2.
UniGene	Hs.515890.
3D structure databases
ProteinModelPortal	P62699.
ModBase	Search...
Protein-protein interaction databases
STRING	P62699.
PTM databases
PhosphoSite	P62699.
Polymorphism databases
DMDM	50428911.
Proteomic databases
PRIDE	P62699.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000261353; ENSP00000261353; ENSG00000119801. ENST00000379519; ENSP00000368834; ENSG00000119801. ENST00000379520; ENSP00000368835; ENSG00000119801. ENST00000402003; ENSP00000383974; ENSG00000119801. ENST00000402708; ENSP00000385278; ENSG00000119801. ENST00000408026; ENSP00000384140; ENSG00000119801.
GeneID	51646.
KEGG	hsa:51646.
UCSC	uc002rmz.2. human.
Organism-specific databases
CTD	51646.
GeneCards	GC02P030369.
H-InvDB	HIX0001942.
HGNC	HGNC:18329. YPEL5.
MIM	609726. gene.
neXtProt	NX_P62699.
PharmGKB	PA134863727.
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG20244.
GeneTree	ENSGT00390000008364.
HOGENOM	HBG524054.
HOVERGEN	HBG054215.
InParanoid	P62699.
OMA	GRVILEY.
OrthoDB	EOG4CC42Q.
PhylomeDB	P62699.
Gene expression databases
ArrayExpress	P62699.
Bgee	P62699.
CleanEx	HS_YPEL5.
Genevestigator	P62699.
GermOnline	ENSG00000119801. Homo sapiens.
Family and domain databases
InterPro	IPR002579. Methionine_sulphoxide_MsrB. IPR004910. Yippee. [Graphical view]
Gene3D	G3DSA:2.170.150.20. MsrB. 1 hit.
Pfam	PF03226. Yippee. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	55592.
SOURCE	Search...

Entry information

Entry name

YPEL5_HUMAN

Accession

Primary (citable) accession number: P62699
Secondary accession number(s): D6W568 , Q65Z97, Q8R174, Q9D6M1, Q9UMX7, Q9Y3C9

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 19, 2004
Last sequence update:	July 19, 2004
Last modified:	January 25, 2012
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.