Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein yippee-like 5

Gene

YPEL5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi17ZincPROSITE-ProRule annotation1
Metal bindingi20ZincPROSITE-ProRule annotation1
Metal bindingi73ZincPROSITE-ProRule annotation1
Metal bindingi76ZincPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-HSA-6798695 Neutrophil degranulation

Names & Taxonomyi

Protein namesi
Recommended name:
Protein yippee-like 5
Gene namesi
Name:YPEL5
ORF Names:CGI-127
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000119801.12
HGNCiHGNC:18329 YPEL5
MIMi609726 gene
neXtProtiNX_P62699

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

DisGeNETi51646
OpenTargetsiENSG00000119801
PharmGKBiPA134863727

Polymorphism and mutation databases

BioMutaiYPEL5
DMDMi50428911

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002123961 – 121Protein yippee-like 5Add BLAST121

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei118PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiP62699
MaxQBiP62699
PaxDbiP62699
PeptideAtlasiP62699
PRIDEiP62699

PTM databases

iPTMnetiP62699
PhosphoSitePlusiP62699

Expressioni

Gene expression databases

BgeeiENSG00000119801
CleanExiHS_YPEL5
GenevisibleiP62699 HS

Organism-specific databases

HPAiHPA042809

Interactioni

Protein-protein interaction databases

BioGridi119655, 33 interactors
IntActiP62699, 22 interactors
MINTiP62699
STRINGi9606.ENSP00000261353

Structurei

3D structure databases

ProteinModelPortaliP62699
SMRiP62699
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 110YippeePROSITE-ProRule annotationAdd BLAST98

Sequence similaritiesi

Belongs to the yippee family.Curated

Phylogenomic databases

eggNOGiKOG3399 Eukaryota
ENOG4111VJ1 LUCA
GeneTreeiENSGT00390000008364
HOGENOMiHOG000184254
HOVERGENiHBG054215
InParanoidiP62699
OMAiNCDAKLG
OrthoDBiEOG091G0XLE
PhylomeDBiP62699
TreeFamiTF323378

Family and domain databases

InterProiView protein in InterPro
IPR034751 Yippee
IPR004910 Yippee/Mis18/Cereblon
PfamiView protein in Pfam
PF03226 Yippee-Mis18, 1 hit
PROSITEiView protein in PROSITE
PS51792 YIPPEE, 1 hit

Sequencei

Sequence statusi: Complete.

P62699-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRIFLDHIG GTRLFSCANC DTILTNRSEL ISTRFTGATG RAFLFNKVVN
60 70 80 90 100
LQYSEVQDRV MLTGRHMVRD VSCKNCNSKL GWIYEFATED SQRYKEGRVI
110 120
LERALVRESE GFEEHVPSDN S
Length:121
Mass (Da):13,842
Last modified:July 19, 2004 - v1
Checksum:iADCF8C4C3B154EAB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB098739 mRNA Translation: BAD51380.1
AF151885 mRNA Translation: AAD34122.1
AF135161 mRNA Translation: AAF43785.1
AC016907 Genomic DNA Translation: AAY14780.1
CH471053 Genomic DNA Translation: EAX00500.1
CH471053 Genomic DNA Translation: EAX00501.1
CH471053 Genomic DNA Translation: EAX00504.1
CH471053 Genomic DNA Translation: EAX00505.1
BC000836 mRNA Translation: AAH00836.1
BC047237 mRNA Translation: AAH47237.1
AF172940 mRNA Translation: AAD47882.1
CCDSiCCDS1771.1
PIRiT50836
RefSeqiNP_001120871.1, NM_001127399.1
NP_001120872.1, NM_001127400.1
NP_001120873.1, NM_001127401.1
NP_057145.1, NM_016061.2
XP_016859807.1, XM_017004318.1
XP_016859808.1, XM_017004319.1
XP_016859809.1, XM_017004320.1
XP_016859810.1, XM_017004321.1
XP_016859811.1, XM_017004322.1
UniGeneiHs.515890

Genome annotation databases

EnsembliENST00000261353; ENSP00000261353; ENSG00000119801
ENST00000379519; ENSP00000368834; ENSG00000119801
ENST00000379520; ENSP00000368835; ENSG00000119801
ENST00000402003; ENSP00000383974; ENSG00000119801
ENST00000402708; ENSP00000385278; ENSG00000119801
GeneIDi51646
KEGGihsa:51646
UCSCiuc002rmz.5 human

Similar proteinsi

Entry informationi

Entry nameiYPEL5_HUMAN
AccessioniPrimary (citable) accession number: P62699
Secondary accession number(s): D6W568
, Q65Z97, Q8R174, Q9D6M1, Q9UMX7, Q9Y3C9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: July 19, 2004
Last modified: May 23, 2018
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health