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P62664 (RS4_THET2) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
30S ribosomal protein S4
Gene names
Name:rpsD
Synonyms:rps4
Ordered Locus Names:TT_C1301
OrganismThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) [Complete proteome] [HAMAP]
Taxonomic identifier262724 [NCBI]
Taxonomic lineageBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus

Protein attributes

Sequence length209 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the body and platform of the 30S subunit By similarity. HAMAP-Rule MF_01306_B

Cofactor

Binds 1 zinc ion per subunit By similarity. HAMAP-Rule MF_01306_B

Subunit structure

Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity By similarity.

Sequence similarities

Belongs to the ribosomal protein S4P family.

Contains 1 S4 RNA-binding domain.

Ontologies

Keywords
   DomainZinc-finger
   LigandMetal-binding
RNA-binding
rRNA-binding
Zinc
   Molecular functionRibonucleoprotein
Ribosomal protein
   Technical term3D-structure
Complete proteome
Gene Ontology (GO)
   Biological_processtranslation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentsmall ribosomal subunit

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

rRNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

structural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 20920830S ribosomal protein S4 HAMAP-Rule MF_01306_B
PRO_0000132482

Regions

Domain100 – 16263S4 RNA-binding
Zinc finger9 – 3123C4-type HAMAP-Rule MF_01306_B

Sites

Metal binding91Zinc By similarity
Metal binding121Zinc By similarity
Metal binding261Zinc By similarity
Metal binding311Zinc By similarity

Secondary structure

......................................... 209
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P62664 [UniParc].

Last modified January 23, 2007. Version 2.
Checksum: 0FF3911816971236

FASTA20924,324
        10         20         30         40         50         60 
MGRYIGPVCR LCRREGVKLY LKGERCYSPK CAMERRPYPP GQHGQKRARR PSDYAVRLRE 

        70         80         90        100        110        120 
KQKLRRIYGI SERQFRNLFE EASKKKGVTG SVFLGLLESR LDNVVYRLGF AVSRRQARQL 

       130        140        150        160        170        180 
VRHGHITVNG RRVDLPSYRV RPGDEIAVAE KSRNLELIRQ NLEAMKGRKV GPWLSLDVEG 

       190        200 
MKGKFLRLPD REDLALPVNE QLVIEFYSR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017221 Genomic DNA. Translation: AAS81643.1.
RefSeqYP_005270.1. NC_005835.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2QNHX-ray3.83e1-209[»]
3D5AX-ray3.21D1-209[»]
3D5CX-ray3.21D1-209[»]
3F1EX-ray3.00D1-209[»]
3F1GX-ray3.00D1-209[»]
3MR8X-ray3.62D2-209[»]
3MS0X-ray3.62D2-209[»]
3PYNX-ray3.50D2-209[»]
3PYQX-ray3.50D2-209[»]
3PYSX-ray3.40D2-209[»]
3PYUX-ray3.40D2-209[»]
4KBTX-ray3.86D2-209[»]
4KBVX-ray3.86D2-209[»]
4KCYX-ray3.50D2-209[»]
4KD0X-ray3.50D2-209[»]
4KD8X-ray3.50D2-209[»]
4KDAX-ray3.50D2-209[»]
4KDGX-ray4.00D2-209[»]
4KDJX-ray4.00D2-209[»]
4KFHX-ray3.40D2-209[»]
4KFKX-ray3.40D2-209[»]
4L6KX-ray3.40D2-209[»]
4L6MX-ray3.40D2-209[»]
ProteinModelPortalP62664.
SMRP62664. Positions 2-209.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING262724.TTC1301.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAS81643; AAS81643; TT_C1301.
GeneID2776390.
KEGGtth:TTC1301.
PATRIC23953009. VBITheThe54392_1293.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0522.
KOK02986.
OMACFSEKCP.
OrthoDBEOG6N3CXM.

Enzyme and pathway databases

BioCycTTHE262724:GCAT-1316-MONOMER.

Family and domain databases

Gene3D1.10.1050.10. 1 hit.
3.10.290.10. 1 hit.
HAMAPMF_01306_B. Ribosomal_S4_B.
InterProIPR022801. Ribosomal_S4/S9.
IPR001912. Ribosomal_S4/S9_N.
IPR005709. Ribosomal_S4_bac-type.
IPR018079. Ribosomal_S4_CS.
IPR002942. S4_RNA-bd.
[Graphical view]
PANTHERPTHR11831. PTHR11831. 1 hit.
PfamPF00163. Ribosomal_S4. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
SMARTSM00363. S4. 1 hit.
[Graphical view]
TIGRFAMsTIGR01017. rpsD_bact. 1 hit.
PROSITEPS00632. RIBOSOMAL_S4. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP62664.

Entry information

Entry nameRS4_THET2
AccessionPrimary (citable) accession number: P62664
Entry history
Integrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: January 23, 2007
Last modified: May 14, 2014
This is version 74 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references