Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

30S ribosomal protein S4

Gene

rpsD

Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the body and platform of the 30S subunit.By similarity

Cofactori

Zn2+By similarityNote: Binds 1 zinc ion per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi9ZincBy similarity1
Metal bindingi12ZincBy similarity1
Metal bindingi26ZincBy similarity1
Metal bindingi31ZincBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri9 – 31C4-typeAdd BLAST23

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

Metal-binding, RNA-binding, rRNA-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
30S ribosomal protein S4
Gene namesi
Name:rpsD
Synonyms:rps4
Ordered Locus Names:TT_C1301
OrganismiThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Taxonomic identifieri262724 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000000592 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001324822 – 20930S ribosomal protein S4Add BLAST208

Proteomic databases

PRIDEiP62664.

Interactioni

Subunit structurei

Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity (By similarity).By similarity

Protein-protein interaction databases

STRINGi262724.TTC1301.

Structurei

Secondary structure

1209
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Turni9 – 11Combined sources3
Helixi12 – 15Combined sources4
Helixi24 – 27Combined sources4
Turni33 – 35Combined sources3
Turni41 – 43Combined sources3
Beta strandi44 – 46Combined sources3
Helixi53 – 68Combined sources16
Helixi72 – 84Combined sources13
Beta strandi85 – 87Combined sources3
Helixi89 – 99Combined sources11
Helixi101 – 107Combined sources7
Beta strandi109 – 113Combined sources5
Helixi114 – 122Combined sources9
Beta strandi126 – 132Combined sources7
Beta strandi145 – 148Combined sources4
Helixi150 – 153Combined sources4
Helixi156 – 163Combined sources8
Beta strandi165 – 167Combined sources3
Beta strandi174 – 177Combined sources4
Turni178 – 181Combined sources4
Beta strandi182 – 185Combined sources4
Helixi191 – 193Combined sources3
Helixi200 – 206Combined sources7

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4KVBX-ray4.20D1-209[»]
4V4IX-ray3.71e1-209[»]
4V4JX-ray3.83e1-209[»]
4V63X-ray3.21AD/CD1-209[»]
4V67X-ray3.00AD/CD1-209[»]
4V7PX-ray3.62AD/DD2-209[»]
4V83X-ray3.50AD/CD2-209[»]
4V84X-ray3.40AD/CD2-209[»]
4V9JX-ray3.86AD/CD2-209[»]
4V9KX-ray3.50AD/CD2-209[»]
4V9LX-ray3.50AD/CD2-209[»]
4V9MX-ray4.00AD/CD2-209[»]
4V9NX-ray3.40AD/CD2-209[»]
4V9QX-ray3.40BD/DD2-209[»]
4W29X-ray3.80AD/CD2-209[»]
4XEJX-ray3.80AS04/BS042-209[»]
5J4DX-ray3.10MA/RC1-209[»]
ProteinModelPortaliP62664.
SMRiP62664.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP62664.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini100 – 162S4 RNA-bindingAdd BLAST63

Sequence similaritiesi

Belongs to the ribosomal protein S4P family.Curated
Contains 1 S4 RNA-binding domain.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri9 – 31C4-typeAdd BLAST23

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiENOG4105G6W. Bacteria.
COG0522. LUCA.
KOiK02986.
OMAiRTSDYGN.

Family and domain databases

Gene3Di1.10.1050.10. 1 hit.
3.10.290.10. 1 hit.
HAMAPiMF_01306_B. Ribosomal_S4_B. 1 hit.
InterProiIPR022801. Ribosomal_S4/S9.
IPR001912. Ribosomal_S4/S9_N.
IPR005709. Ribosomal_S4_bac-type.
IPR018079. Ribosomal_S4_CS.
IPR002942. S4_RNA-bd.
[Graphical view]
PANTHERiPTHR11831. PTHR11831. 1 hit.
PfamiPF00163. Ribosomal_S4. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
SMARTiSM01390. Ribosomal_S4. 1 hit.
SM00363. S4. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01017. rpsD_bact. 1 hit.
PROSITEiPS00632. RIBOSOMAL_S4. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P62664-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRYIGPVCR LCRREGVKLY LKGERCYSPK CAMERRPYPP GQHGQKRARR
60 70 80 90 100
PSDYAVRLRE KQKLRRIYGI SERQFRNLFE EASKKKGVTG SVFLGLLESR
110 120 130 140 150
LDNVVYRLGF AVSRRQARQL VRHGHITVNG RRVDLPSYRV RPGDEIAVAE
160 170 180 190 200
KSRNLELIRQ NLEAMKGRKV GPWLSLDVEG MKGKFLRLPD REDLALPVNE

QLVIEFYSR
Length:209
Mass (Da):24,324
Last modified:January 23, 2007 - v2
Checksum:i0FF3911816971236
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017221 Genomic DNA. Translation: AAS81643.1.
RefSeqiWP_011173699.1. NC_005835.1.

Genome annotation databases

EnsemblBacteriaiAAS81643; AAS81643; TT_C1301.
KEGGitth:TT_C1301.
PATRICi23953009. VBITheThe54392_1293.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017221 Genomic DNA. Translation: AAS81643.1.
RefSeqiWP_011173699.1. NC_005835.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4KVBX-ray4.20D1-209[»]
4V4IX-ray3.71e1-209[»]
4V4JX-ray3.83e1-209[»]
4V63X-ray3.21AD/CD1-209[»]
4V67X-ray3.00AD/CD1-209[»]
4V7PX-ray3.62AD/DD2-209[»]
4V83X-ray3.50AD/CD2-209[»]
4V84X-ray3.40AD/CD2-209[»]
4V9JX-ray3.86AD/CD2-209[»]
4V9KX-ray3.50AD/CD2-209[»]
4V9LX-ray3.50AD/CD2-209[»]
4V9MX-ray4.00AD/CD2-209[»]
4V9NX-ray3.40AD/CD2-209[»]
4V9QX-ray3.40BD/DD2-209[»]
4W29X-ray3.80AD/CD2-209[»]
4XEJX-ray3.80AS04/BS042-209[»]
5J4DX-ray3.10MA/RC1-209[»]
ProteinModelPortaliP62664.
SMRiP62664.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi262724.TTC1301.

Proteomic databases

PRIDEiP62664.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAS81643; AAS81643; TT_C1301.
KEGGitth:TT_C1301.
PATRICi23953009. VBITheThe54392_1293.

Phylogenomic databases

eggNOGiENOG4105G6W. Bacteria.
COG0522. LUCA.
KOiK02986.
OMAiRTSDYGN.

Miscellaneous databases

EvolutionaryTraceiP62664.

Family and domain databases

Gene3Di1.10.1050.10. 1 hit.
3.10.290.10. 1 hit.
HAMAPiMF_01306_B. Ribosomal_S4_B. 1 hit.
InterProiIPR022801. Ribosomal_S4/S9.
IPR001912. Ribosomal_S4/S9_N.
IPR005709. Ribosomal_S4_bac-type.
IPR018079. Ribosomal_S4_CS.
IPR002942. S4_RNA-bd.
[Graphical view]
PANTHERiPTHR11831. PTHR11831. 1 hit.
PfamiPF00163. Ribosomal_S4. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
SMARTiSM01390. Ribosomal_S4. 1 hit.
SM00363. S4. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01017. rpsD_bact. 1 hit.
PROSITEiPS00632. RIBOSOMAL_S4. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRS4_THET2
AccessioniPrimary (citable) accession number: P62664
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: January 23, 2007
Last modified: November 2, 2016
This is version 93 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.