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P62664

- RS4_THET2

UniProt

P62664 - RS4_THET2

Protein

30S ribosomal protein S4

Gene

rpsD

Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 2 (23 Jan 2007)
      Previous versions | rss
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    Functioni

    One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the body and platform of the 30S subunit.By similarity

    Cofactori

    Binds 1 zinc ion per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi9 – 91ZincBy similarity
    Metal bindingi12 – 121ZincBy similarity
    Metal bindingi26 – 261ZincBy similarity
    Metal bindingi31 – 311ZincBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri9 – 3123C4-typeAdd
    BLAST

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. rRNA binding Source: UniProtKB-HAMAP
    3. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. translation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Keywords - Ligandi

    Metal-binding, RNA-binding, rRNA-binding, Zinc

    Enzyme and pathway databases

    BioCyciTTHE262724:GCAT-1316-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    30S ribosomal protein S4
    Gene namesi
    Name:rpsD
    Synonyms:rps4
    Ordered Locus Names:TT_C1301
    OrganismiThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
    Taxonomic identifieri262724 [NCBI]
    Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
    ProteomesiUP000000592: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. small ribosomal subunit Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11RemovedBy similarity
    Chaini2 – 20920830S ribosomal protein S4PRO_0000132482Add
    BLAST

    Interactioni

    Subunit structurei

    Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity By similarity.By similarity

    Protein-protein interaction databases

    STRINGi262724.TTC1301.

    Structurei

    Secondary structure

    1
    209
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Turni9 – 113
    Helixi12 – 154
    Helixi24 – 274
    Turni33 – 353
    Turni41 – 433
    Beta strandi44 – 463
    Helixi53 – 6816
    Helixi72 – 8413
    Beta strandi85 – 873
    Helixi89 – 9911
    Helixi101 – 1077
    Beta strandi109 – 1135
    Helixi114 – 1229
    Beta strandi126 – 1327
    Beta strandi145 – 1484
    Helixi150 – 1534
    Helixi156 – 1638
    Beta strandi165 – 1673
    Beta strandi174 – 1774
    Turni178 – 1814
    Beta strandi182 – 1854
    Helixi191 – 1933
    Helixi200 – 2067

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2QNHX-ray3.83e1-209[»]
    3D5AX-ray3.21D1-209[»]
    3D5CX-ray3.21D1-209[»]
    3F1EX-ray3.00D1-209[»]
    3F1GX-ray3.00D1-209[»]
    3MR8X-ray3.62D2-209[»]
    3MS0X-ray3.62D2-209[»]
    3PYNX-ray3.50D2-209[»]
    3PYQX-ray3.50D2-209[»]
    3PYSX-ray3.40D2-209[»]
    3PYUX-ray3.40D2-209[»]
    4KBTX-ray3.86D2-209[»]
    4KBVX-ray3.86D2-209[»]
    4KCYX-ray3.50D2-209[»]
    4KD0X-ray3.50D2-209[»]
    4KD8X-ray3.50D2-209[»]
    4KDAX-ray3.50D2-209[»]
    4KDGX-ray4.00D2-209[»]
    4KDJX-ray4.00D2-209[»]
    4KFHX-ray3.40D2-209[»]
    4KFKX-ray3.40D2-209[»]
    4KVBX-ray4.20D1-209[»]
    4L6KX-ray3.40D2-209[»]
    4L6MX-ray3.40D2-209[»]
    ProteinModelPortaliP62664.
    SMRiP62664. Positions 2-209.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP62664.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini100 – 16263S4 RNA-bindingAdd
    BLAST

    Sequence similaritiesi

    Belongs to the ribosomal protein S4P family.Curated
    Contains 1 S4 RNA-binding domain.Curated

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri9 – 3123C4-typeAdd
    BLAST

    Keywords - Domaini

    Zinc-finger

    Phylogenomic databases

    eggNOGiCOG0522.
    KOiK02986.
    OMAiCFSEKCP.
    OrthoDBiEOG6N3CXM.

    Family and domain databases

    Gene3Di1.10.1050.10. 1 hit.
    3.10.290.10. 1 hit.
    HAMAPiMF_01306_B. Ribosomal_S4_B.
    InterProiIPR022801. Ribosomal_S4/S9.
    IPR001912. Ribosomal_S4/S9_N.
    IPR005709. Ribosomal_S4_bac-type.
    IPR018079. Ribosomal_S4_CS.
    IPR002942. S4_RNA-bd.
    [Graphical view]
    PANTHERiPTHR11831. PTHR11831. 1 hit.
    PfamiPF00163. Ribosomal_S4. 1 hit.
    PF01479. S4. 1 hit.
    [Graphical view]
    SMARTiSM00363. S4. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01017. rpsD_bact. 1 hit.
    PROSITEiPS00632. RIBOSOMAL_S4. 1 hit.
    PS50889. S4. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P62664-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGRYIGPVCR LCRREGVKLY LKGERCYSPK CAMERRPYPP GQHGQKRARR    50
    PSDYAVRLRE KQKLRRIYGI SERQFRNLFE EASKKKGVTG SVFLGLLESR 100
    LDNVVYRLGF AVSRRQARQL VRHGHITVNG RRVDLPSYRV RPGDEIAVAE 150
    KSRNLELIRQ NLEAMKGRKV GPWLSLDVEG MKGKFLRLPD REDLALPVNE 200
    QLVIEFYSR 209
    Length:209
    Mass (Da):24,324
    Last modified:January 23, 2007 - v2
    Checksum:i0FF3911816971236
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017221 Genomic DNA. Translation: AAS81643.1.
    RefSeqiYP_005270.1. NC_005835.1.

    Genome annotation databases

    EnsemblBacteriaiAAS81643; AAS81643; TT_C1301.
    GeneIDi2776390.
    KEGGitth:TTC1301.
    PATRICi23953009. VBITheThe54392_1293.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017221 Genomic DNA. Translation: AAS81643.1 .
    RefSeqi YP_005270.1. NC_005835.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2QNH X-ray 3.83 e 1-209 [» ]
    3D5A X-ray 3.21 D 1-209 [» ]
    3D5C X-ray 3.21 D 1-209 [» ]
    3F1E X-ray 3.00 D 1-209 [» ]
    3F1G X-ray 3.00 D 1-209 [» ]
    3MR8 X-ray 3.62 D 2-209 [» ]
    3MS0 X-ray 3.62 D 2-209 [» ]
    3PYN X-ray 3.50 D 2-209 [» ]
    3PYQ X-ray 3.50 D 2-209 [» ]
    3PYS X-ray 3.40 D 2-209 [» ]
    3PYU X-ray 3.40 D 2-209 [» ]
    4KBT X-ray 3.86 D 2-209 [» ]
    4KBV X-ray 3.86 D 2-209 [» ]
    4KCY X-ray 3.50 D 2-209 [» ]
    4KD0 X-ray 3.50 D 2-209 [» ]
    4KD8 X-ray 3.50 D 2-209 [» ]
    4KDA X-ray 3.50 D 2-209 [» ]
    4KDG X-ray 4.00 D 2-209 [» ]
    4KDJ X-ray 4.00 D 2-209 [» ]
    4KFH X-ray 3.40 D 2-209 [» ]
    4KFK X-ray 3.40 D 2-209 [» ]
    4KVB X-ray 4.20 D 1-209 [» ]
    4L6K X-ray 3.40 D 2-209 [» ]
    4L6M X-ray 3.40 D 2-209 [» ]
    ProteinModelPortali P62664.
    SMRi P62664. Positions 2-209.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 262724.TTC1301.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAS81643 ; AAS81643 ; TT_C1301 .
    GeneIDi 2776390.
    KEGGi tth:TTC1301.
    PATRICi 23953009. VBITheThe54392_1293.

    Phylogenomic databases

    eggNOGi COG0522.
    KOi K02986.
    OMAi CFSEKCP.
    OrthoDBi EOG6N3CXM.

    Enzyme and pathway databases

    BioCyci TTHE262724:GCAT-1316-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei P62664.

    Family and domain databases

    Gene3Di 1.10.1050.10. 1 hit.
    3.10.290.10. 1 hit.
    HAMAPi MF_01306_B. Ribosomal_S4_B.
    InterProi IPR022801. Ribosomal_S4/S9.
    IPR001912. Ribosomal_S4/S9_N.
    IPR005709. Ribosomal_S4_bac-type.
    IPR018079. Ribosomal_S4_CS.
    IPR002942. S4_RNA-bd.
    [Graphical view ]
    PANTHERi PTHR11831. PTHR11831. 1 hit.
    Pfami PF00163. Ribosomal_S4. 1 hit.
    PF01479. S4. 1 hit.
    [Graphical view ]
    SMARTi SM00363. S4. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01017. rpsD_bact. 1 hit.
    PROSITEi PS00632. RIBOSOMAL_S4. 1 hit.
    PS50889. S4. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HB27 / ATCC BAA-163 / DSM 7039.

    Entry informationi

    Entry nameiRS4_THET2
    AccessioniPrimary (citable) accession number: P62664
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 19, 2004
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 76 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3