Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P62663

- RS3_THET2

UniProt

P62663 - RS3_THET2

Protein

30S ribosomal protein S3

Gene

rpsC

Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 80 (01 Oct 2014)
      Sequence version 2 (23 Jan 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation By similarity.By similarity

    GO - Molecular functioni

    1. mRNA binding Source: UniProtKB-HAMAP
    2. rRNA binding Source: UniProtKB-HAMAP
    3. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. translation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Keywords - Ligandi

    RNA-binding, rRNA-binding

    Enzyme and pathway databases

    BioCyciTTHE262724:GCAT-1337-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    30S ribosomal protein S3
    Gene namesi
    Name:rpsC
    Synonyms:rps3
    Ordered Locus Names:TT_C1322
    OrganismiThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
    Taxonomic identifieri262724 [NCBI]
    Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
    ProteomesiUP000000592: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. small ribosomal subunit Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11RemovedBy similarity
    Chaini2 – 23923830S ribosomal protein S3PRO_0000130222Add
    BLAST

    Interactioni

    Subunit structurei

    Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14 By similarity.By similarity

    Protein-protein interaction databases

    STRINGi262724.TTC1322.

    Structurei

    Secondary structure

    1
    239
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi7 – 104
    Turni11 – 155
    Beta strandi19 – 224
    Turni26 – 283
    Helixi29 – 4517
    Helixi48 – 503
    Beta strandi52 – 554
    Beta strandi57 – 659
    Beta strandi68 – 714
    Helixi74 – 774
    Turni78 – 814
    Helixi83 – 9210
    Beta strandi95 – 984
    Beta strandi101 – 1055
    Helixi109 – 1113
    Helixi113 – 12513
    Helixi130 – 14314
    Beta strandi147 – 1559
    Helixi157 – 1593
    Beta strandi164 – 1663
    Beta strandi169 – 1713
    Beta strandi175 – 1784
    Beta strandi182 – 1876
    Beta strandi196 – 2038

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2OW8X-ray3.71d1-239[»]
    2QNHX-ray3.83d1-239[»]
    3D5AX-ray3.21C1-239[»]
    3D5CX-ray3.21C1-239[»]
    3F1EX-ray3.00C1-239[»]
    3F1GX-ray3.00C1-239[»]
    3MR8X-ray3.62C2-207[»]
    3MS0X-ray3.62C2-207[»]
    3PYNX-ray3.50C2-207[»]
    3PYQX-ray3.50C2-207[»]
    3PYSX-ray3.40C2-207[»]
    3PYUX-ray3.40C2-207[»]
    4KBTX-ray3.86C2-208[»]
    4KBVX-ray3.86C2-208[»]
    4KCYX-ray3.50C2-208[»]
    4KD0X-ray3.50C2-208[»]
    4KD8X-ray3.50C2-208[»]
    4KDAX-ray3.50C2-208[»]
    4KDGX-ray4.00C2-208[»]
    4KDJX-ray4.00C2-208[»]
    4KFHX-ray3.40C2-207[»]
    4KFKX-ray3.40C2-207[»]
    4KVBX-ray4.20C1-239[»]
    4L6KX-ray3.40C2-207[»]
    4L6MX-ray3.40C2-207[»]
    ProteinModelPortaliP62663.
    SMRiP62663. Positions 2-207.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP62663.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini40 – 10869KH type-2Add
    BLAST

    Sequence similaritiesi

    Belongs to the ribosomal protein S3P family.Curated
    Contains 1 KH type-2 domain.Curated

    Phylogenomic databases

    eggNOGiCOG0092.
    KOiK02982.
    OMAiVEYAFTE.
    OrthoDBiEOG6K13X3.

    Family and domain databases

    Gene3Di3.30.1140.32. 1 hit.
    3.30.300.20. 1 hit.
    HAMAPiMF_01309_B. Ribosomal_S3_B.
    InterProiIPR004087. KH_dom.
    IPR015946. KH_dom-like_a/b.
    IPR004044. KH_dom_type_2.
    IPR009019. KH_prok-type.
    IPR005704. Ribosomal_S3_bac.
    IPR001351. Ribosomal_S3_C.
    IPR018280. Ribosomal_S3_CS.
    [Graphical view]
    PfamiPF07650. KH_2. 1 hit.
    PF00189. Ribosomal_S3_C. 1 hit.
    [Graphical view]
    SMARTiSM00322. KH. 1 hit.
    [Graphical view]
    SUPFAMiSSF54814. SSF54814. 1 hit.
    SSF54821. SSF54821. 1 hit.
    TIGRFAMsiTIGR01009. rpsC_bact. 1 hit.
    PROSITEiPS50823. KH_TYPE_2. 1 hit.
    PS00548. RIBOSOMAL_S3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P62663-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGNKIHPIGF RLGITRDWES RWYAGKKQYR HLLLEDQRIR GLLEKELYSA    50
    GLARVDIERA ADNVAVTVHV AKPGVVIGRG GERIRVLREE LAKLTGKNVA 100
    LNVQEVQNPN LSAPLVAQRV AEQIERRFAV RRAIKQAVQR VMESGAKGAK 150
    VIVSGRIGGA EQARTEWAAQ GRVPLHTLRA NIDYGFALAR TTYGVLGVKA 200
    YIFLGEVIGG QKPKARPELP KAEERPRRRR PAVRVKKEE 239
    Length:239
    Mass (Da):26,701
    Last modified:January 23, 2007 - v2
    Checksum:iAD585A1D53AC7F04
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ409330 Genomic DNA. Translation: CAC35062.1.
    AE017221 Genomic DNA. Translation: AAS81664.1.
    RefSeqiYP_005291.1. NC_005835.1.

    Genome annotation databases

    EnsemblBacteriaiAAS81664; AAS81664; TT_C1322.
    GeneIDi2775806.
    KEGGitth:TTC1322.
    PATRICi23953051. VBITheThe54392_1314.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ409330 Genomic DNA. Translation: CAC35062.1 .
    AE017221 Genomic DNA. Translation: AAS81664.1 .
    RefSeqi YP_005291.1. NC_005835.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2OW8 X-ray 3.71 d 1-239 [» ]
    2QNH X-ray 3.83 d 1-239 [» ]
    3D5A X-ray 3.21 C 1-239 [» ]
    3D5C X-ray 3.21 C 1-239 [» ]
    3F1E X-ray 3.00 C 1-239 [» ]
    3F1G X-ray 3.00 C 1-239 [» ]
    3MR8 X-ray 3.62 C 2-207 [» ]
    3MS0 X-ray 3.62 C 2-207 [» ]
    3PYN X-ray 3.50 C 2-207 [» ]
    3PYQ X-ray 3.50 C 2-207 [» ]
    3PYS X-ray 3.40 C 2-207 [» ]
    3PYU X-ray 3.40 C 2-207 [» ]
    4KBT X-ray 3.86 C 2-208 [» ]
    4KBV X-ray 3.86 C 2-208 [» ]
    4KCY X-ray 3.50 C 2-208 [» ]
    4KD0 X-ray 3.50 C 2-208 [» ]
    4KD8 X-ray 3.50 C 2-208 [» ]
    4KDA X-ray 3.50 C 2-208 [» ]
    4KDG X-ray 4.00 C 2-208 [» ]
    4KDJ X-ray 4.00 C 2-208 [» ]
    4KFH X-ray 3.40 C 2-207 [» ]
    4KFK X-ray 3.40 C 2-207 [» ]
    4KVB X-ray 4.20 C 1-239 [» ]
    4L6K X-ray 3.40 C 2-207 [» ]
    4L6M X-ray 3.40 C 2-207 [» ]
    ProteinModelPortali P62663.
    SMRi P62663. Positions 2-207.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 262724.TTC1322.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAS81664 ; AAS81664 ; TT_C1322 .
    GeneIDi 2775806.
    KEGGi tth:TTC1322.
    PATRICi 23953051. VBITheThe54392_1314.

    Phylogenomic databases

    eggNOGi COG0092.
    KOi K02982.
    OMAi VEYAFTE.
    OrthoDBi EOG6K13X3.

    Enzyme and pathway databases

    BioCyci TTHE262724:GCAT-1337-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei P62663.

    Family and domain databases

    Gene3Di 3.30.1140.32. 1 hit.
    3.30.300.20. 1 hit.
    HAMAPi MF_01309_B. Ribosomal_S3_B.
    InterProi IPR004087. KH_dom.
    IPR015946. KH_dom-like_a/b.
    IPR004044. KH_dom_type_2.
    IPR009019. KH_prok-type.
    IPR005704. Ribosomal_S3_bac.
    IPR001351. Ribosomal_S3_C.
    IPR018280. Ribosomal_S3_CS.
    [Graphical view ]
    Pfami PF07650. KH_2. 1 hit.
    PF00189. Ribosomal_S3_C. 1 hit.
    [Graphical view ]
    SMARTi SM00322. KH. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54814. SSF54814. 1 hit.
    SSF54821. SSF54821. 1 hit.
    TIGRFAMsi TIGR01009. rpsC_bact. 1 hit.
    PROSITEi PS50823. KH_TYPE_2. 1 hit.
    PS00548. RIBOSOMAL_S3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3."
      Pioletti M., Schluenzen F., Harms J., Zarivach R., Gluehmann M., Avila H., Bashan A., Bartels H., Auerbach T., Jacobi C., Hartsch T., Yonath A., Franceschi F.
      EMBO J. 20:1829-1839(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HB27 / ATCC BAA-163 / DSM 7039.

    Entry informationi

    Entry nameiRS3_THET2
    AccessioniPrimary (citable) accession number: P62663
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 19, 2004
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 80 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3