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Protein

30S ribosomal protein S3

Gene

rpsC

Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciTTHE262724:GCAT-1337-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
30S ribosomal protein S3
Gene namesi
Name:rpsC
Synonyms:rps3
Ordered Locus Names:TT_C1322
OrganismiThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Taxonomic identifieri262724 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
ProteomesiUP000000592 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 23923830S ribosomal protein S3PRO_0000130222Add
BLAST

Interactioni

Subunit structurei

Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14 (By similarity).By similarity

Protein-protein interaction databases

STRINGi262724.TTC1322.

Structurei

Secondary structure

1
239
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi7 – 104Combined sources
Turni11 – 155Combined sources
Beta strandi19 – 224Combined sources
Turni26 – 283Combined sources
Helixi29 – 4517Combined sources
Helixi48 – 503Combined sources
Beta strandi52 – 554Combined sources
Beta strandi57 – 659Combined sources
Beta strandi68 – 714Combined sources
Helixi74 – 774Combined sources
Turni78 – 814Combined sources
Helixi83 – 9210Combined sources
Beta strandi95 – 984Combined sources
Beta strandi101 – 1055Combined sources
Helixi109 – 1113Combined sources
Helixi113 – 12513Combined sources
Helixi130 – 14314Combined sources
Beta strandi147 – 1559Combined sources
Helixi157 – 1593Combined sources
Beta strandi164 – 1663Combined sources
Beta strandi169 – 1713Combined sources
Beta strandi175 – 1784Combined sources
Beta strandi182 – 1876Combined sources
Beta strandi196 – 2038Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4KVBX-ray4.20C1-239[»]
4V4IX-ray3.71d1-239[»]
4V4JX-ray3.83d1-239[»]
4V63X-ray3.21AC/CC1-239[»]
4V67X-ray3.00AC/CC1-239[»]
4V7PX-ray3.62AC/DC2-207[»]
4V83X-ray3.50AC/CC2-207[»]
4V84X-ray3.40AC/CC2-207[»]
4V9JX-ray3.86AC/CC2-208[»]
4V9KX-ray3.50AC/CC2-208[»]
4V9LX-ray3.50AC/CC2-208[»]
4V9MX-ray4.00AC/CC2-208[»]
4V9NX-ray3.40AC/CC2-207[»]
4V9QX-ray3.40BC/DC2-207[»]
4W29X-ray3.80AC/CC2-208[»]
4XEJX-ray3.80AS03/BS032-207[»]
ProteinModelPortaliP62663.
SMRiP62663. Positions 2-207.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP62663.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini40 – 10869KH type-2Add
BLAST

Sequence similaritiesi

Belongs to the ribosomal protein S3P family.Curated
Contains 1 KH type-2 domain.Curated

Phylogenomic databases

eggNOGiCOG0092.
KOiK02982.
OMAiKTNPIGN.
OrthoDBiEOG6K13X3.

Family and domain databases

Gene3Di3.30.1140.32. 1 hit.
3.30.300.20. 1 hit.
HAMAPiMF_01309_B. Ribosomal_S3_B.
InterProiIPR004087. KH_dom.
IPR015946. KH_dom-like_a/b.
IPR004044. KH_dom_type_2.
IPR009019. KH_prok-type.
IPR005704. Ribosomal_S3_bac.
IPR001351. Ribosomal_S3_C.
IPR018280. Ribosomal_S3_CS.
[Graphical view]
PfamiPF07650. KH_2. 1 hit.
PF00189. Ribosomal_S3_C. 1 hit.
[Graphical view]
SMARTiSM00322. KH. 1 hit.
[Graphical view]
SUPFAMiSSF54814. SSF54814. 1 hit.
SSF54821. SSF54821. 1 hit.
TIGRFAMsiTIGR01009. rpsC_bact. 1 hit.
PROSITEiPS50823. KH_TYPE_2. 1 hit.
PS00548. RIBOSOMAL_S3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P62663-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNKIHPIGF RLGITRDWES RWYAGKKQYR HLLLEDQRIR GLLEKELYSA
60 70 80 90 100
GLARVDIERA ADNVAVTVHV AKPGVVIGRG GERIRVLREE LAKLTGKNVA
110 120 130 140 150
LNVQEVQNPN LSAPLVAQRV AEQIERRFAV RRAIKQAVQR VMESGAKGAK
160 170 180 190 200
VIVSGRIGGA EQARTEWAAQ GRVPLHTLRA NIDYGFALAR TTYGVLGVKA
210 220 230
YIFLGEVIGG QKPKARPELP KAEERPRRRR PAVRVKKEE
Length:239
Mass (Da):26,701
Last modified:January 23, 2007 - v2
Checksum:iAD585A1D53AC7F04
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ409330 Genomic DNA. Translation: CAC35062.1.
AE017221 Genomic DNA. Translation: AAS81664.1.
RefSeqiWP_008633418.1. NC_005835.1.

Genome annotation databases

EnsemblBacteriaiAAS81664; AAS81664; TT_C1322.
KEGGitth:TTC1322.
PATRICi23953051. VBITheThe54392_1314.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ409330 Genomic DNA. Translation: CAC35062.1.
AE017221 Genomic DNA. Translation: AAS81664.1.
RefSeqiWP_008633418.1. NC_005835.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4KVBX-ray4.20C1-239[»]
4V4IX-ray3.71d1-239[»]
4V4JX-ray3.83d1-239[»]
4V63X-ray3.21AC/CC1-239[»]
4V67X-ray3.00AC/CC1-239[»]
4V7PX-ray3.62AC/DC2-207[»]
4V83X-ray3.50AC/CC2-207[»]
4V84X-ray3.40AC/CC2-207[»]
4V9JX-ray3.86AC/CC2-208[»]
4V9KX-ray3.50AC/CC2-208[»]
4V9LX-ray3.50AC/CC2-208[»]
4V9MX-ray4.00AC/CC2-208[»]
4V9NX-ray3.40AC/CC2-207[»]
4V9QX-ray3.40BC/DC2-207[»]
4W29X-ray3.80AC/CC2-208[»]
4XEJX-ray3.80AS03/BS032-207[»]
ProteinModelPortaliP62663.
SMRiP62663. Positions 2-207.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi262724.TTC1322.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAS81664; AAS81664; TT_C1322.
KEGGitth:TTC1322.
PATRICi23953051. VBITheThe54392_1314.

Phylogenomic databases

eggNOGiCOG0092.
KOiK02982.
OMAiKTNPIGN.
OrthoDBiEOG6K13X3.

Enzyme and pathway databases

BioCyciTTHE262724:GCAT-1337-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP62663.

Family and domain databases

Gene3Di3.30.1140.32. 1 hit.
3.30.300.20. 1 hit.
HAMAPiMF_01309_B. Ribosomal_S3_B.
InterProiIPR004087. KH_dom.
IPR015946. KH_dom-like_a/b.
IPR004044. KH_dom_type_2.
IPR009019. KH_prok-type.
IPR005704. Ribosomal_S3_bac.
IPR001351. Ribosomal_S3_C.
IPR018280. Ribosomal_S3_CS.
[Graphical view]
PfamiPF07650. KH_2. 1 hit.
PF00189. Ribosomal_S3_C. 1 hit.
[Graphical view]
SMARTiSM00322. KH. 1 hit.
[Graphical view]
SUPFAMiSSF54814. SSF54814. 1 hit.
SSF54821. SSF54821. 1 hit.
TIGRFAMsiTIGR01009. rpsC_bact. 1 hit.
PROSITEiPS50823. KH_TYPE_2. 1 hit.
PS00548. RIBOSOMAL_S3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3."
    Pioletti M., Schluenzen F., Harms J., Zarivach R., Gluehmann M., Avila H., Bashan A., Bartels H., Auerbach T., Jacobi C., Hartsch T., Yonath A., Franceschi F.
    EMBO J. 20:1829-1839(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HB27 / ATCC BAA-163 / DSM 7039.

Entry informationi

Entry nameiRS3_THET2
AccessioniPrimary (citable) accession number: P62663
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: January 23, 2007
Last modified: July 22, 2015
This is version 89 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.