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Protein

Tripartite motif-containing protein 26

Gene

Trim26

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri16 – 57RING-typePROSITE-ProRule annotationAdd BLAST42
Zinc fingeri97 – 138B box-typePROSITE-ProRule annotationAdd BLAST42

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-RNO-877300. Interferon gamma signaling.

Names & Taxonomyi

Protein namesi
Recommended name:
Tripartite motif-containing protein 26
Alternative name(s):
Zinc finger protein 173
Gene namesi
Name:Trim26
Synonyms:Znf173
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 20

Organism-specific databases

RGDi1359126. Trim26.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000562391 – 542Tripartite motif-containing protein 26Add BLAST542

Proteomic databases

PaxDbiP62603.
PRIDEiP62603.

Expressioni

Gene expression databases

BgeeiENSRNOG00000032930.
ExpressionAtlasiP62603. differential.
GenevisibleiP62603. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000001019.

Structurei

3D structure databases

ProteinModelPortaliP62603.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini298 – 542B30.2/SPRYPROSITE-ProRule annotationAdd BLAST245

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili197 – 243Sequence analysisAdd BLAST47
Coiled coili411 – 440Sequence analysisAdd BLAST30

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi384 – 403Poly-GluAdd BLAST20

Sequence similaritiesi

Belongs to the TRIM/RBCC family.Curated
Contains 1 B box-type zinc finger.PROSITE-ProRule annotation
Contains 1 B30.2/SPRY domain.PROSITE-ProRule annotation
Contains 1 RING-type zinc finger.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri16 – 57RING-typePROSITE-ProRule annotationAdd BLAST42
Zinc fingeri97 – 138B box-typePROSITE-ProRule annotationAdd BLAST42

Keywords - Domaini

Coiled coil, Zinc-finger

Phylogenomic databases

eggNOGiKOG2177. Eukaryota.
ENOG410Z766. LUCA.
GeneTreeiENSGT00760000118893.
HOGENOMiHOG000234133.
HOVERGENiHBG001357.
InParanoidiP62603.
KOiK12008.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
4.10.45.10. 1 hit.
InterProiIPR001870. B30.2/SPRY.
IPR003879. Butyrophylin.
IPR013320. ConA-like_dom.
IPR006574. PRY.
IPR003877. SPRY_dom.
IPR000315. Znf_B-box.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF13765. PRY. 1 hit.
PF00622. SPRY. 1 hit.
PF00643. zf-B_box. 1 hit.
[Graphical view]
PRINTSiPR01407. BUTYPHLNCDUF.
SMARTiSM00336. BBOX. 1 hit.
SM00589. PRY. 1 hit.
SM00184. RING. 1 hit.
SM00449. SPRY. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 2 hits.
PROSITEiPS50188. B302_SPRY. 1 hit.
PS50119. ZF_BBOX. 1 hit.
PS50089. ZF_RING_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P62603-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVSAPLRSL EEEVTCSICL DYLRDPVTID CGHVFCRSCT SDIRPISGNR
60 70 80 90 100
PVCPLCKKPF KKENIRPVWQ LASLVENIER LKVDNGKQPG ELAREPQDMK
110 120 130 140 150
LCERHQEKLH YYCEDDGKLL CVMCRESREH RPHTAVLVEK AALPHREKIL
160 170 180 190 200
NHLNTLRRDR DKIQGFQAKG EADILAALTK LQEQRQYIVA EFKQGHQFLK
210 220 230 240 250
KREQHLLDQL ATLEQLLTEG REKFKTRGVS ELDRLTLVIS ELEGKARQPA
260 270 280 290 300
AELMQLSDRL SCLSLRYPRK KFWIGKAIPH MVKRKAGEFS DKLLSLQRGL
310 320 330 340 350
RQFQGKLLRD LEYKTVSVTL DPQSASGYLQ LSEDWKCITY TGQYQSDCLL
360 370 380 390 400
PQQFDCEPGV LGSKGFTWGK VYWEVELERE GWSEDEEEGE EEEEGEEEEE
410 420 430 440 450
DEEPGYGDRY EDWETDEEDE SLGEEEEEEE EEEEEVQESC MVGVAKDSVK
460 470 480 490 500
RKGNLSLRPE DGVWALRLSP SGIWANTSPE AQLFPVLRPR RVGIALDYEG
510 520 530 540
GTVTFTNAES QELIYTFTTT FTRRLVPFLW LKWPEARLLL RP
Length:542
Mass (Da):62,631
Last modified:July 19, 2004 - v1
Checksum:i88C87B17F9E57BA6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX883051 Genomic DNA. Translation: CAE84057.1.
RefSeqiNP_001011665.1. NM_001011665.2.
UniGeneiRn.163420.

Genome annotation databases

EnsembliENSRNOT00000001019; ENSRNOP00000001019; ENSRNOG00000032930.
GeneIDi309586.
KEGGirno:309586.
UCSCiRGD:1359126. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX883051 Genomic DNA. Translation: CAE84057.1.
RefSeqiNP_001011665.1. NM_001011665.2.
UniGeneiRn.163420.

3D structure databases

ProteinModelPortaliP62603.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000001019.

Proteomic databases

PaxDbiP62603.
PRIDEiP62603.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000001019; ENSRNOP00000001019; ENSRNOG00000032930.
GeneIDi309586.
KEGGirno:309586.
UCSCiRGD:1359126. rat.

Organism-specific databases

CTDi7726.
RGDi1359126. Trim26.

Phylogenomic databases

eggNOGiKOG2177. Eukaryota.
ENOG410Z766. LUCA.
GeneTreeiENSGT00760000118893.
HOGENOMiHOG000234133.
HOVERGENiHBG001357.
InParanoidiP62603.
KOiK12008.

Enzyme and pathway databases

ReactomeiR-RNO-877300. Interferon gamma signaling.

Miscellaneous databases

PROiP62603.

Gene expression databases

BgeeiENSRNOG00000032930.
ExpressionAtlasiP62603. differential.
GenevisibleiP62603. RN.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
4.10.45.10. 1 hit.
InterProiIPR001870. B30.2/SPRY.
IPR003879. Butyrophylin.
IPR013320. ConA-like_dom.
IPR006574. PRY.
IPR003877. SPRY_dom.
IPR000315. Znf_B-box.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF13765. PRY. 1 hit.
PF00622. SPRY. 1 hit.
PF00643. zf-B_box. 1 hit.
[Graphical view]
PRINTSiPR01407. BUTYPHLNCDUF.
SMARTiSM00336. BBOX. 1 hit.
SM00589. PRY. 1 hit.
SM00184. RING. 1 hit.
SM00449. SPRY. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 2 hits.
PROSITEiPS50188. B302_SPRY. 1 hit.
PS50119. ZF_BBOX. 1 hit.
PS50089. ZF_RING_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTRI26_RAT
AccessioniPrimary (citable) accession number: P62603
Secondary accession number(s): Q6MFZ0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: July 19, 2004
Last modified: November 30, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.