Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P62464 (UPPP_DESVH) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Synonyms:bacA, upk
Ordered Locus Names:DVU_1660
OrganismDesulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / NCIMB 8303) [Reference proteome] [HAMAP]
Taxonomic identifier882 [NCBI]
Taxonomic lineageBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio

Protein attributes

Sequence length265 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 265265Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000151145

Regions

Transmembrane42 – 6221Helical; Potential
Transmembrane82 – 10221Helical; Potential
Transmembrane108 – 12821Helical; Potential
Transmembrane143 – 16321Helical; Potential
Transmembrane181 – 20121Helical; Potential
Transmembrane221 – 24121Helical; Potential
Transmembrane248 – 26417Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P62464 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 551C9335B79F236E

FASTA26528,820
        10         20         30         40         50         60 
MSDMITAAIL GLVEGLTEFL PVSSTGHLII TGELLGFTGP KATTFEVAIQ LGAILAVVVL 

        70         80         90        100        110        120 
YWDRFWGLLR PQPYVRFAGL RGIMLLLLTS LPASVLGLAA HSTIKAHLFT PSTVAIALAV 

       130        140        150        160        170        180 
GAIFMLLVER RTERPRYMTL DEMSPALALG IGCFQCLALW PGFSRSAATI MGGMLLGARR 

       190        200        210        220        230        240 
GLAAEYSFIA AVPIMFAATG YDLLKSWTLF TPADLPFFAT GFVVSFLSAW AAVKLFIALV 

       250        260 
GRMTFRPFAW YRLAIAPLVY YFMAY 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017285 Genomic DNA. Translation: AAS96137.1.
RefSeqYP_010878.1. NC_002937.3.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING882.DVU1660.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAS96137; AAS96137; DVU_1660.
GeneID2795899.
KEGGdvu:DVU1660.
PATRIC32063116. VBIDesVul119526_1533.

Phylogenomic databases

eggNOGCOG1968.
KOK06153.
OMAFNDAHAK.
OrthoDBEOG6QP13M.
PhylomeDBP62464.

Enzyme and pathway databases

BioCycDVUL882:GJIL-1699-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_DESVH
AccessionPrimary (citable) accession number: P62464
Entry history
Integrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families