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P62421

- PGK_TREDE

UniProt

P62421 - PGK_TREDE

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Protein

Phosphoglycerate kinase

Gene
pgk, TDE_1715
Organism
Treponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei35 – 351Substrate By similarity
Binding sitei136 – 1361Substrate By similarity
Binding sitei173 – 1731Substrate By similarity
Binding sitei224 – 2241ATP By similarity
Binding sitei315 – 3151ATP; via carbonyl oxygen By similarity
Binding sitei346 – 3461ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi375 – 3784ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciTDEN243275:GJ7G-1744-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:TDE_1715
OrganismiTreponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222)
Taxonomic identifieri243275 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
ProteomesiUP000008212: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 419419Phosphoglycerate kinaseUniRule annotationPRO_0000146029Add
BLAST

Proteomic databases

PRIDEiP62421.

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi243275.TDE1715.

Structurei

3D structure databases

ProteinModelPortaliP62421.
SMRiP62421. Positions 3-418.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni20 – 223Substrate binding By similarity
Regioni59 – 624Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
KOiK00927.
OMAiFNVPLRE.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.

Sequencei

Sequence statusi: Complete.

P62421-1 [UniParc]FASTAAdd to Basket

« Hide

MIKTVKDVNL KDKRIIMRVD FNVPMKDGVV QDDTRIRAAL PTIKYILEQG    50
ARSLVLMSHL GDPSKDAKKA KEKAEKDGKP FDEEAYINGK HRMKPVAEYL 100
SGLLKLPVDF APSCMGQLER VKALPQGGIL MLENTRFHKE ETSKEKAEQQ 150
ILAKELSLYG DIYVNDAFGT AHRSHASTAE IANFVNTRVA GFLMEKEIKY 200
LEPMLNNPAK PMTAIIGGAK VSSKIAVLES LLKNASSLII GGGMAYTFLK 250
VQGKKIGKSL FEEDFMDTAK NLLDKAEKQG VKIILPVDHI CSETFSPNAE 300
AVLVESTDIP DNLMGMDVGP KTLALYKEII LSSKSIVWNG PVGVFEFEAF 350
SKGTEETARL VAAATEKGAL TIVGGGDSVA AVNKFNLADK MSHVSTGGGA 400
SLEFLEGKVL PGIACLDTI 419
Length:419
Mass (Da):45,463
Last modified:July 5, 2004 - v1
Checksum:i8C0D9AE16A9BE6DD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017226 Genomic DNA. Translation: AAS12230.1.
RefSeqiNP_972319.1. NC_002967.9.

Genome annotation databases

EnsemblBacteriaiAAS12230; AAS12230; TDE_1715.
GeneIDi2740887.
KEGGitde:TDE1715.
PATRICi20525590. VBITreDen445_1640.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017226 Genomic DNA. Translation: AAS12230.1 .
RefSeqi NP_972319.1. NC_002967.9.

3D structure databases

ProteinModelPortali P62421.
SMRi P62421. Positions 3-418.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243275.TDE1715.

Proteomic databases

PRIDEi P62421.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAS12230 ; AAS12230 ; TDE_1715 .
GeneIDi 2740887.
KEGGi tde:TDE1715.
PATRICi 20525590. VBITreDen445_1640.

Phylogenomic databases

eggNOGi COG0126.
KOi K00927.
OMAi FNVPLRE.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci TDEN243275:GJ7G-1744-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35405 / CIP 103919 / DSM 14222.

Entry informationi

Entry nameiPGK_TREDE
AccessioniPrimary (citable) accession number: P62421
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: July 5, 2004
Last modified: June 11, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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