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P62417 (PGK_ONYPE) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:PAM_174
OrganismOnion yellows phytoplasma (strain OY-M) [Complete proteome] [HAMAP]
Taxonomic identifier262768 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesAcholeplasmatalesAcholeplasmataceaeCandidatus PhytoplasmaCandidatus Phytoplasma asteris

Protein attributes

Sequence length398 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 398398Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000145979

Regions

Nucleotide binding354 – 3574ATP By similarity
Region20 – 223Substrate binding By similarity
Region58 – 614Substrate binding By similarity

Sites

Binding site351Substrate By similarity
Binding site1181Substrate By similarity
Binding site1551Substrate By similarity
Binding site2061ATP By similarity
Binding site2951ATP; via carbonyl oxygen By similarity
Binding site3261ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
P62417 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 11D26EC9F797615C

FASTA39843,522
        10         20         30         40         50         60 
MTKSLTNMNI TNKKVLLRAD LNVPLENSVI TDDNRIKAIL PTLKYLVQQK AKVIIFSHLG 

        70         80         90        100        110        120 
RVKTEADKAH FSLQVVAEKI AFYLQQKLKF VPETQGNTLN QAVGQMLPGD VLVVQNTRFE 

       130        140        150        160        170        180 
DVPFKKESKN DPELGKYWAS LGDVFVNDAF GTCHRTHASN VGIATYIKEK CFGFLVEKEI 

       190        200        210        220        230        240 
SFLKKIVQTP QRPLVAVLGG SKVSDKIGVI RSLLQKVDVL LIGGGMSYTC LKAKCFNIGT 

       250        260        270        280        290        300 
SLLEADKIPL VKELLASPEG KKIVLPKDFV CGKEFSPTTQ AAVYSYDNIS DDVMGLDIGP 

       310        320        330        340        350        360 
QTIELFKTYL QTAQTVVWNG PVGVFEFEQF SKGTKALAET ISNLSPNTTT IIGGGDSAAA 

       370        380        390 
VFKFGLDQNF SHISTGGGAF LEFLEGKPMP GLACMEKL 

« Hide

References

[1]"Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma."
Oshima K., Kakizawa S., Nishigawa H., Jung H.-Y., Wei W., Suzuki S., Arashida R., Nakata D., Miyata S., Ugaki M., Namba S.
Nat. Genet. 36:27-29(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: OY-M.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP006628 Genomic DNA. Translation: BAD04259.1.
RefSeqNP_950426.1. NC_005303.2.

3D structure databases

ProteinModelPortalP62417.
SMRP62417. Positions 2-397.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING262768.PAM_174.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAD04259; BAD04259; PAM_174.
GeneID2673203.
KEGGpoy:PAM_174.
PATRIC22809834. VBIOniYel86799_0240.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227107.
KOK00927.
OMAFNVPLRE.
OrthoDBEOG64N9Z0.

Enzyme and pathway databases

BioCycMORG262768:GHF5-181-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_ONYPE
AccessionPrimary (citable) accession number: P62417
Entry history
Integrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: July 5, 2004
Last modified: June 11, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways