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P62415

- PGK_MYCMS

UniProt

P62415 - PGK_MYCMS

Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Mycoplasma mycoides subsp. mycoides SC (strain PG1)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 67 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei39 – 391SubstrateUniRule annotation
    Binding sitei122 – 1221SubstrateUniRule annotation
    Binding sitei163 – 1631SubstrateUniRule annotation
    Binding sitei214 – 2141ATPUniRule annotation
    Binding sitei300 – 3001ATP; via carbonyl oxygenUniRule annotation
    Binding sitei331 – 3311ATPUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi360 – 3634ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciMMYC272632:GI1G-662-MONOMER.
    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
    Gene namesi
    Name:pgkUniRule annotation
    Ordered Locus Names:MSC_0678
    OrganismiMycoplasma mycoides subsp. mycoides SC (strain PG1)
    Taxonomic identifieri272632 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
    ProteomesiUP000001016: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 404404Phosphoglycerate kinasePRO_0000145968Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi272632.MSC_0678.

    Structurei

    3D structure databases

    ProteinModelPortaliP62415.
    SMRiP62415. Positions 5-404.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni24 – 263Substrate bindingUniRule annotation
    Regioni62 – 654Substrate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0126.
    HOGENOMiHOG000227107.
    KOiK00927.
    OMAiFPVDYVT.
    OrthoDBiEOG64N9Z0.

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPiMF_00145. Phosphoglyc_kinase.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.
    PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P62415-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNYNNKKTLK DIDVKNKTVL VRVDFNVPIQ NGVITDDNRI IAAFPTINYL    50
    LENDAKIVLF SHLSRIKSKE DKLKKSLAPV AKRLEELLNK QVKFINQTRG 100
    QELEKAISSL QSKEIILVEN TRFEDVLDDQ VVKYESKNNS ELGKYWASLG 150
    EVFVNDAFGT AHRAHASNVG IASNIKVSAI GFLVEKELKM LFQAVNEPKK 200
    PFIAILGGAK VSDKIGVIEN LLPKVDKLLI GGGMSYTFLK ALGKTIGKSL 250
    LEEDKIDLAK HYLEIGKDKI VVPVDTACAK EFADVSPTIF EGNIPDEWDG 300
    LDAGPKTIEL FKQEIKKAKT IVWNGPVGVF EFKNFENGTK SVCQAIAEQT 350
    QNGAFTLIGG GDSASAAINM GFKDKFSWIS TGGGASLEFM EGKELLGISA 400
    IQDK 404
    Length:404
    Mass (Da):44,414
    Last modified:July 5, 2004 - v1
    Checksum:iC5E55A8D2398B95C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX293980 Genomic DNA. Translation: CAE77297.1.
    RefSeqiNP_975655.1. NC_005364.2.
    WP_011166849.1. NC_005364.2.

    Genome annotation databases

    EnsemblBacteriaiCAE77297; CAE77297; MSC_0678.
    GeneIDi2744555.
    KEGGimmy:MSC_0678.
    PATRICi20018177. VBIMycMyc4973_0730.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX293980 Genomic DNA. Translation: CAE77297.1 .
    RefSeqi NP_975655.1. NC_005364.2.
    WP_011166849.1. NC_005364.2.

    3D structure databases

    ProteinModelPortali P62415.
    SMRi P62415. Positions 5-404.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272632.MSC_0678.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAE77297 ; CAE77297 ; MSC_0678 .
    GeneIDi 2744555.
    KEGGi mmy:MSC_0678.
    PATRICi 20018177. VBIMycMyc4973_0730.

    Phylogenomic databases

    eggNOGi COG0126.
    HOGENOMi HOG000227107.
    KOi K00927.
    OMAi FPVDYVT.
    OrthoDBi EOG64N9Z0.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .
    BioCyci MMYC272632:GI1G-662-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPi MF_00145. Phosphoglyc_kinase.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Mycoplasma mycoides subsp. mycoides SC type strain PG1T, the causative agent of contagious bovine pleuropneumonia (CBPP)."
      Westberg J., Persson A., Holmberg A., Goesmann A., Lundeberg J., Johansson K.-E., Pettersson B., Uhlen M.
      Genome Res. 14:221-227(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PG1.

    Entry informationi

    Entry nameiPGK_MYCMS
    AccessioniPrimary (citable) accession number: P62415
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 67 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3