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P62414 (PGK_LEPIC) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein attributes

Sequence length396 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 396396Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000145958

Regions

Nucleotide binding349 – 3524ATP By similarity
Region21 – 233Substrate binding By similarity
Region59 – 624Substrate binding By similarity

Sites

Binding site361Substrate By similarity
Binding site1181Substrate By similarity
Binding site1511Substrate By similarity
Binding site2011ATP By similarity
Binding site2921ATP; via carbonyl oxygen By similarity
Binding site3231ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
P62414 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 61F789BA1D5EA7EF

FASTA39643,002
        10         20         30         40         50         60 
MELPRLENVD LSGKRVFLRV DFNVPVENGK VTDKTRIEKT LPTIELLIKK GARIIIASHL 

        70         80         90        100        110        120 
GRPKGQVNPE FSLAPVVETF QSLVKSKVYF SKTVIGEDAI KLSKELKNGE ILVIENVRFH 

       130        140        150        160        170        180 
KEEEENDPGF SKKLAALADI YVNDAFGAAH RAHSSTEGIA RLLPAYAGLL MHKEILELSA 

       190        200        210        220        230        240 
LLHKPARPFV AIIGGSKVST KIKVLTNLFD KVNHLLIGGG MAYTFLKSRA IPIGNSLVEK 

       250        260        270        280        290        300 
EFEVQAFQLI EKAGVAGIDL QLPVDHIIGD QFNEKAKTKS VDKMGILDGW MGMDIGSKTV 

       310        320        330        340        350        360 
SNYEKIIKNA GTIFWNGPMG VFEMDKFASG TMAIAKAVAK SKAKTVVGGG DSIAAINKAR 

       370        380        390 
VADKITHIST GGGASLEFME GRKLPGVEAL KKKTSE 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016823 Genomic DNA. Translation: AAS70662.1.
RefSeqYP_002025.1. NC_005823.1.

3D structure databases

ProteinModelPortalP62414.
SMRP62414. Positions 1-393.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING267671.LIC12091.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAS70662; AAS70662; LIC_12091.
GeneID2769661.
KEGGlic:LIC12091.
PATRIC22376664. VBILepInt6257_2492.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00927.
OMADMIFDIG.
OrthoDBEOG64N9Z0.
ProtClustDBPRK00073.

Enzyme and pathway databases

BioCycLINT267671:GHQI-2083-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_LEPIC
AccessionPrimary (citable) accession number: P62414
Entry history
Integrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: July 5, 2004
Last modified: February 19, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways