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Protein

Protein BTG1

Gene

Btg1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Anti-proliferative protein.By similarity

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Protein BTG1
Alternative name(s):
B-cell translocation gene 1 protein
Gene namesi
Name:Btg1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:88215. Btg1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Keywords - Diseasei

Proto-oncogene

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001438011 – 171Protein BTG1Add BLAST171

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei159PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP62325.
PRIDEiP62325.

PTM databases

iPTMnetiP62325.
PhosphoSitePlusiP62325.

Expressioni

Gene expression databases

BgeeiENSMUSG00000036478.
CleanExiMM_BTG1.
ExpressionAtlasiP62325. baseline and differential.
GenevisibleiP62325. MM.

Interactioni

Subunit structurei

Interacts with CNOT7 and CNOT8.By similarity

GO - Molecular functioni

Protein-protein interaction databases

BioGridi198397. 2 interactors.
MINTiMINT-118196.
STRINGi10090.ENSMUSP00000038863.

Structurei

3D structure databases

ProteinModelPortaliP62325.
SMRiP62325.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the BTG family.Curated

Phylogenomic databases

eggNOGiKOG4006. Eukaryota.
ENOG410ZZC0. LUCA.
GeneTreeiENSGT00550000074461.
HOGENOMiHOG000290200.
HOVERGENiHBG004907.
InParanoidiP62325.
KOiK14443.
OMAiGHVNDRQ.
OrthoDBiEOG091G0RS0.
PhylomeDBiP62325.
TreeFamiTF105272.

Family and domain databases

InterProiView protein in InterPro
IPR002087. Anti_prolifrtn.
IPR033330. BTG1.
PANTHERiPTHR22978:SF36. PTHR22978:SF36. 1 hit.
PfamiView protein in Pfam
PF07742. BTG. 1 hit.
PRINTSiPR00310. ANTIPRLFBTG1.
SMARTiView protein in SMART
SM00099. btg1. 1 hit.
SUPFAMiSSF160696. SSF160696. 1 hit.
PROSITEiView protein in PROSITE
PS00960. BTG_1. 1 hit.
PS01203. BTG_2. 1 hit.

Sequencei

Sequence statusi: Complete.

P62325-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHPFYTRAAT MIGEIAAAVS FISKFLRTKG LTSERQLQTF SQSLQELLAE
60 70 80 90 100
HYKHHWFPEK PCKGSGYRCI RINHKMDPLI GQAAQRIGLS SQELFRLLPS
110 120 130 140 150
ELTLWVDPYE VSYRIGEDGS ICVLYEASPA GGSTQNSTNV QMVDSRISCK
160 170
EELLLGRTSP SKNYNMMTVS G
Length:171
Mass (Da):19,209
Last modified:July 5, 2004 - v1
Checksum:iEFED8BE09013BE60
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z16410 Genomic DNA. Translation: CAA78902.1.
L16846 mRNA. Translation: AAA37327.1.
BC006834 mRNA. Translation: AAH06834.1.
BC018309 mRNA. Translation: AAH18309.1.
CCDSiCCDS24140.1.
PIRiI48272.
RefSeqiNP_031595.1. NM_007569.2.
UniGeneiMm.23811.

Genome annotation databases

EnsembliENSMUST00000038377; ENSMUSP00000038863; ENSMUSG00000036478.
GeneIDi12226.
KEGGimmu:12226.
UCSCiuc007gww.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiBTG1_MOUSE
AccessioniPrimary (citable) accession number: P62325
Secondary accession number(s): P31607
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: July 5, 2004
Last modified: September 27, 2017
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families