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Protein

Protein BTG1

Gene

Btg1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Anti-proliferative protein.By similarity

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Protein BTG1
Alternative name(s):
B-cell translocation gene 1 protein
Gene namesi
Name:Btg1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:88215 Btg1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Keywords - Diseasei

Proto-oncogene

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001438011 – 171Protein BTG1Add BLAST171

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei159PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP62325
PRIDEiP62325

PTM databases

iPTMnetiP62325
PhosphoSitePlusiP62325

Expressioni

Gene expression databases

BgeeiENSMUSG00000036478
CleanExiMM_BTG1
ExpressionAtlasiP62325 baseline and differential
GenevisibleiP62325 MM

Interactioni

Subunit structurei

Interacts with CNOT7 and CNOT8.By similarity

GO - Molecular functioni

Protein-protein interaction databases

BioGridi198397, 2 interactors
STRINGi10090.ENSMUSP00000038863

Structurei

3D structure databases

ProteinModelPortaliP62325
SMRiP62325
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the BTG family.Curated

Phylogenomic databases

eggNOGiKOG4006 Eukaryota
ENOG410ZZC0 LUCA
GeneTreeiENSGT00550000074461
HOGENOMiHOG000290200
HOVERGENiHBG004907
InParanoidiP62325
KOiK14443
OMAiGHVNDRQ
OrthoDBiEOG091G0RS0
PhylomeDBiP62325
TreeFamiTF105272

Family and domain databases

Gene3Di1.20.120.1120, 1 hit
InterProiView protein in InterPro
IPR002087 Anti_prolifrtn
IPR036054 BTG-like_sf
IPR033330 BTG1
PANTHERiPTHR22978:SF30 PTHR22978:SF30, 1 hit
PfamiView protein in Pfam
PF07742 BTG, 1 hit
PRINTSiPR00310 ANTIPRLFBTG1
SMARTiView protein in SMART
SM00099 btg1, 1 hit
SUPFAMiSSF160696 SSF160696, 1 hit
PROSITEiView protein in PROSITE
PS00960 BTG_1, 1 hit
PS01203 BTG_2, 1 hit

Sequencei

Sequence statusi: Complete.

P62325-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHPFYTRAAT MIGEIAAAVS FISKFLRTKG LTSERQLQTF SQSLQELLAE
60 70 80 90 100
HYKHHWFPEK PCKGSGYRCI RINHKMDPLI GQAAQRIGLS SQELFRLLPS
110 120 130 140 150
ELTLWVDPYE VSYRIGEDGS ICVLYEASPA GGSTQNSTNV QMVDSRISCK
160 170
EELLLGRTSP SKNYNMMTVS G
Length:171
Mass (Da):19,209
Last modified:July 5, 2004 - v1
Checksum:iEFED8BE09013BE60
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z16410 Genomic DNA Translation: CAA78902.1
L16846 mRNA Translation: AAA37327.1
BC006834 mRNA Translation: AAH06834.1
BC018309 mRNA Translation: AAH18309.1
CCDSiCCDS24140.1
PIRiI48272
RefSeqiNP_031595.1, NM_007569.2
UniGeneiMm.23811

Genome annotation databases

EnsembliENSMUST00000038377; ENSMUSP00000038863; ENSMUSG00000036478
GeneIDi12226
KEGGimmu:12226
UCSCiuc007gww.2 mouse

Similar proteinsi

Entry informationi

Entry nameiBTG1_MOUSE
AccessioniPrimary (citable) accession number: P62325
Secondary accession number(s): P31607
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: July 5, 2004
Last modified: March 28, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health