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P62281

- RS11_MOUSE

UniProt

P62281 - RS11_MOUSE

Protein

40S ribosomal protein S11

Gene

Rps11

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. rRNA binding Source: UniProtKB-KW
    2. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. translation Source: InterPro

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Keywords - Ligandi

    RNA-binding, rRNA-binding

    Enzyme and pathway databases

    ReactomeiREACT_196445. SRP-dependent cotranslational protein targeting to membrane.
    REACT_198524. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_198528. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    40S ribosomal protein S11
    Gene namesi
    Name:Rps11
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 7

    Organism-specific databases

    MGIiMGI:1351329. Rps11.

    Subcellular locationi

    GO - Cellular componenti

    1. ribosome Source: UniProtKB-KW

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11RemovedBy similarity
    Chaini2 – 15815740S ribosomal protein S11PRO_0000128511Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei2 – 21N-acetylalanineBy similarity
    Modified residuei22 – 221Citrulline1 Publication
    Modified residuei38 – 381N6-acetyllysine1 Publication
    Modified residuei45 – 451N6-acetyllysine1 Publication
    Modified residuei58 – 581N6-acetyllysine1 Publication
    Lipidationi60 – 601S-palmitoyl cysteineBy similarity

    Post-translational modificationi

    Citrullinated by PADI4.1 Publication

    Keywords - PTMi

    Acetylation, Citrullination, Lipoprotein, Palmitate

    Proteomic databases

    MaxQBiP62281.
    PaxDbiP62281.
    PRIDEiP62281.

    PTM databases

    PhosphoSiteiP62281.

    Expressioni

    Gene expression databases

    BgeeiP62281.
    CleanExiMM_RPS11.
    GenevestigatoriP62281.

    Interactioni

    Protein-protein interaction databases

    BioGridi205129. 9 interactions.
    DIPiDIP-59975N.
    IntActiP62281. 2 interactions.
    MINTiMINT-1857199.

    Structurei

    3D structure databases

    ProteinModelPortaliP62281.
    SMRiP62281. Positions 1-158.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein S17P family.Curated

    Phylogenomic databases

    eggNOGiCOG0186.
    HOGENOMiHOG000231341.
    HOVERGENiHBG004670.
    KOiK02949.
    OMAiESINFFT.
    OrthoDBiEOG78H3VQ.
    PhylomeDBiP62281.
    TreeFamiTF300126.

    Family and domain databases

    Gene3Di2.40.50.140. 1 hit.
    HAMAPiMF_01345_B. Ribosomal_S17_B.
    InterProiIPR012340. NA-bd_OB-fold.
    IPR000266. Ribosomal_S17.
    IPR028333. Ribosomal_S17_arc-typ.
    IPR019979. Ribosomal_S17_CS.
    [Graphical view]
    PANTHERiPTHR10744. PTHR10744. 1 hit.
    PfamiPF00366. Ribosomal_S17. 1 hit.
    [Graphical view]
    PRINTSiPR00973. RIBOSOMALS17.
    ProDomiPD001295. Ribosomal_S17. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR03630. arch_S17P. 1 hit.
    PROSITEiPS00056. RIBOSOMAL_S17. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P62281-1 [UniParc]FASTAAdd to Basket

    « Hide

    MADIQTERAY QKQPTIFQNK KRVLLGETGK EKLPRYYKNI GLGFKTPKEA    50
    IEGTYIDKKC PFTGNVSIRG RILSGVVTKM KMQRTIVIRR DYLHYIRKYN 100
    RFEKRHKNMS VHLSPCFRDV QIGDIVTVGE CRPLSKTVRF NVLKVTKAAG 150
    TKKQFQKF 158
    Length:158
    Mass (Da):18,431
    Last modified:January 23, 2007 - v3
    Checksum:i9FB75DC1D99614B0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U93864 mRNA. Translation: AAB52256.1.
    AB028894 Genomic DNA. Translation: BAA88216.1.
    BC012641 mRNA. Translation: AAH12641.1.
    CCDSiCCDS39947.1.
    RefSeqiNP_038753.1. NM_013725.4.
    UniGeneiMm.196538.
    Mm.389435.

    Genome annotation databases

    EnsembliENSMUST00000003521; ENSMUSP00000003521; ENSMUSG00000003429.
    GeneIDi27207.
    KEGGimmu:27207.
    UCSCiuc009gth.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U93864 mRNA. Translation: AAB52256.1 .
    AB028894 Genomic DNA. Translation: BAA88216.1 .
    BC012641 mRNA. Translation: AAH12641.1 .
    CCDSi CCDS39947.1.
    RefSeqi NP_038753.1. NM_013725.4.
    UniGenei Mm.196538.
    Mm.389435.

    3D structure databases

    ProteinModelPortali P62281.
    SMRi P62281. Positions 1-158.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 205129. 9 interactions.
    DIPi DIP-59975N.
    IntActi P62281. 2 interactions.
    MINTi MINT-1857199.

    PTM databases

    PhosphoSitei P62281.

    Proteomic databases

    MaxQBi P62281.
    PaxDbi P62281.
    PRIDEi P62281.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000003521 ; ENSMUSP00000003521 ; ENSMUSG00000003429 .
    GeneIDi 27207.
    KEGGi mmu:27207.
    UCSCi uc009gth.2. mouse.

    Organism-specific databases

    CTDi 6205.
    MGIi MGI:1351329. Rps11.

    Phylogenomic databases

    eggNOGi COG0186.
    HOGENOMi HOG000231341.
    HOVERGENi HBG004670.
    KOi K02949.
    OMAi ESINFFT.
    OrthoDBi EOG78H3VQ.
    PhylomeDBi P62281.
    TreeFami TF300126.

    Enzyme and pathway databases

    Reactomei REACT_196445. SRP-dependent cotranslational protein targeting to membrane.
    REACT_198524. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_198528. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

    Miscellaneous databases

    ChiTaRSi RPS11. mouse.
    NextBioi 24099.
    PROi P62281.
    SOURCEi Search...

    Gene expression databases

    Bgeei P62281.
    CleanExi MM_RPS11.
    Genevestigatori P62281.

    Family and domain databases

    Gene3Di 2.40.50.140. 1 hit.
    HAMAPi MF_01345_B. Ribosomal_S17_B.
    InterProi IPR012340. NA-bd_OB-fold.
    IPR000266. Ribosomal_S17.
    IPR028333. Ribosomal_S17_arc-typ.
    IPR019979. Ribosomal_S17_CS.
    [Graphical view ]
    PANTHERi PTHR10744. PTHR10744. 1 hit.
    Pfami PF00366. Ribosomal_S17. 1 hit.
    [Graphical view ]
    PRINTSi PR00973. RIBOSOMALS17.
    ProDomi PD001295. Ribosomal_S17. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR03630. arch_S17P. 1 hit.
    PROSITEi PS00056. RIBOSOMAL_S17. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Rocha D., Anderson E., Botcherby M., Jordan B.
      Submitted (APR-1997) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: C57BL/6.
    2. "Gene organization and sequence of the region containing the ribosomal protein genes RPL13A and RPS11 in the human genome and conserved features in the mouse genome."
      Higa S., Yoshihama M., Tanaka T., Kenmochi N.
      Gene 240:371-377(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    4. Cited for: CITRULLINATION AT ARG-22.
    5. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
      Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-38; LYS-45 AND LYS-58, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Embryonic fibroblast.

    Entry informationi

    Entry nameiRS11_MOUSE
    AccessioniPrimary (citable) accession number: P62281
    Secondary accession number(s): P04643
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 13, 1987
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 86 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3