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P62281

- RS11_MOUSE

UniProt

P62281 - RS11_MOUSE

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Protein

40S ribosomal protein S11

Gene

Rps11

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. poly(A) RNA binding Source: Ensembl
  2. rRNA binding Source: UniProtKB-KW
  3. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. translation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Enzyme and pathway databases

ReactomeiREACT_196445. SRP-dependent cotranslational protein targeting to membrane.
REACT_198524. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
REACT_198528. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
REACT_231519. Eukaryotic Translation Termination.
REACT_236458. Ribosomal scanning and start codon recognition.
REACT_249044. Formation of a pool of free 40S subunits.
REACT_249316. Formation of the ternary complex, and subsequently, the 43S complex.
REACT_253640. Peptide chain elongation.
REACT_256488. Translation initiation complex formation.
REACT_259469. L13a-mediated translational silencing of Ceruloplasmin expression.
REACT_262078. GTP hydrolysis and joining of the 60S ribosomal subunit.

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S11
Gene namesi
Name:Rps11
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 7

Organism-specific databases

MGIiMGI:1351329. Rps11.

Subcellular locationi

GO - Cellular componenti

  1. cytosolic small ribosomal subunit Source: Ensembl
  2. extracellular vesicular exosome Source: Ensembl
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 15815740S ribosomal protein S11PRO_0000128511Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanineBy similarity
Modified residuei22 – 221Citrulline1 Publication
Modified residuei38 – 381N6-acetyllysine1 Publication
Modified residuei45 – 451N6-acetyllysine1 Publication
Modified residuei58 – 581N6-acetyllysine1 Publication
Lipidationi60 – 601S-palmitoyl cysteineBy similarity

Post-translational modificationi

Citrullinated by PADI4.1 Publication

Keywords - PTMi

Acetylation, Citrullination, Lipoprotein, Palmitate

Proteomic databases

MaxQBiP62281.
PaxDbiP62281.
PRIDEiP62281.

PTM databases

PhosphoSiteiP62281.

Expressioni

Gene expression databases

BgeeiP62281.
CleanExiMM_RPS11.
ExpressionAtlasiP62281. baseline and differential.
GenevestigatoriP62281.

Interactioni

Protein-protein interaction databases

BioGridi205129. 9 interactions.
DIPiDIP-59975N.
IntActiP62281. 2 interactions.
MINTiMINT-1857199.

Structurei

3D structure databases

ProteinModelPortaliP62281.
SMRiP62281. Positions 2-153.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S17P family.Curated

Phylogenomic databases

eggNOGiCOG0186.
HOGENOMiHOG000231341.
HOVERGENiHBG004670.
InParanoidiP62281.
KOiK02949.
OMAiESINFFT.
OrthoDBiEOG78H3VQ.
PhylomeDBiP62281.
TreeFamiTF300126.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_01345_B. Ribosomal_S17_B.
InterProiIPR012340. NA-bd_OB-fold.
IPR000266. Ribosomal_S17.
IPR028333. Ribosomal_S17_arc-typ.
IPR019979. Ribosomal_S17_CS.
[Graphical view]
PANTHERiPTHR10744. PTHR10744. 1 hit.
PfamiPF00366. Ribosomal_S17. 1 hit.
[Graphical view]
PRINTSiPR00973. RIBOSOMALS17.
ProDomiPD001295. Ribosomal_S17. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR03630. arch_S17P. 1 hit.
PROSITEiPS00056. RIBOSOMAL_S17. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P62281-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MADIQTERAY QKQPTIFQNK KRVLLGETGK EKLPRYYKNI GLGFKTPKEA
60 70 80 90 100
IEGTYIDKKC PFTGNVSIRG RILSGVVTKM KMQRTIVIRR DYLHYIRKYN
110 120 130 140 150
RFEKRHKNMS VHLSPCFRDV QIGDIVTVGE CRPLSKTVRF NVLKVTKAAG

TKKQFQKF
Length:158
Mass (Da):18,431
Last modified:January 23, 2007 - v3
Checksum:i9FB75DC1D99614B0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U93864 mRNA. Translation: AAB52256.1.
AB028894 Genomic DNA. Translation: BAA88216.1.
BC012641 mRNA. Translation: AAH12641.1.
CCDSiCCDS39947.1.
RefSeqiNP_038753.1. NM_013725.4.
UniGeneiMm.196538.
Mm.389435.

Genome annotation databases

EnsembliENSMUST00000003521; ENSMUSP00000003521; ENSMUSG00000003429.
GeneIDi27207.
KEGGimmu:27207.
UCSCiuc009gth.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U93864 mRNA. Translation: AAB52256.1 .
AB028894 Genomic DNA. Translation: BAA88216.1 .
BC012641 mRNA. Translation: AAH12641.1 .
CCDSi CCDS39947.1.
RefSeqi NP_038753.1. NM_013725.4.
UniGenei Mm.196538.
Mm.389435.

3D structure databases

ProteinModelPortali P62281.
SMRi P62281. Positions 2-153.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 205129. 9 interactions.
DIPi DIP-59975N.
IntActi P62281. 2 interactions.
MINTi MINT-1857199.

PTM databases

PhosphoSitei P62281.

Proteomic databases

MaxQBi P62281.
PaxDbi P62281.
PRIDEi P62281.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000003521 ; ENSMUSP00000003521 ; ENSMUSG00000003429 .
GeneIDi 27207.
KEGGi mmu:27207.
UCSCi uc009gth.2. mouse.

Organism-specific databases

CTDi 6205.
MGIi MGI:1351329. Rps11.

Phylogenomic databases

eggNOGi COG0186.
HOGENOMi HOG000231341.
HOVERGENi HBG004670.
InParanoidi P62281.
KOi K02949.
OMAi ESINFFT.
OrthoDBi EOG78H3VQ.
PhylomeDBi P62281.
TreeFami TF300126.

Enzyme and pathway databases

Reactomei REACT_196445. SRP-dependent cotranslational protein targeting to membrane.
REACT_198524. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
REACT_198528. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
REACT_231519. Eukaryotic Translation Termination.
REACT_236458. Ribosomal scanning and start codon recognition.
REACT_249044. Formation of a pool of free 40S subunits.
REACT_249316. Formation of the ternary complex, and subsequently, the 43S complex.
REACT_253640. Peptide chain elongation.
REACT_256488. Translation initiation complex formation.
REACT_259469. L13a-mediated translational silencing of Ceruloplasmin expression.
REACT_262078. GTP hydrolysis and joining of the 60S ribosomal subunit.

Miscellaneous databases

ChiTaRSi Rps11. mouse.
NextBioi 24099.
PROi P62281.
SOURCEi Search...

Gene expression databases

Bgeei P62281.
CleanExi MM_RPS11.
ExpressionAtlasi P62281. baseline and differential.
Genevestigatori P62281.

Family and domain databases

Gene3Di 2.40.50.140. 1 hit.
HAMAPi MF_01345_B. Ribosomal_S17_B.
InterProi IPR012340. NA-bd_OB-fold.
IPR000266. Ribosomal_S17.
IPR028333. Ribosomal_S17_arc-typ.
IPR019979. Ribosomal_S17_CS.
[Graphical view ]
PANTHERi PTHR10744. PTHR10744. 1 hit.
Pfami PF00366. Ribosomal_S17. 1 hit.
[Graphical view ]
PRINTSi PR00973. RIBOSOMALS17.
ProDomi PD001295. Ribosomal_S17. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SUPFAMi SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR03630. arch_S17P. 1 hit.
PROSITEi PS00056. RIBOSOMAL_S17. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Rocha D., Anderson E., Botcherby M., Jordan B.
    Submitted (APR-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: C57BL/6.
  2. "Gene organization and sequence of the region containing the ribosomal protein genes RPL13A and RPS11 in the human genome and conserved features in the mouse genome."
    Higa S., Yoshihama M., Tanaka T., Kenmochi N.
    Gene 240:371-377(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  4. Cited for: CITRULLINATION AT ARG-22.
  5. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
    Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
    Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-38; LYS-45 AND LYS-58, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Embryonic fibroblast.

Entry informationi

Entry nameiRS11_MOUSE
AccessioniPrimary (citable) accession number: P62281
Secondary accession number(s): P04643
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 13, 1987
Last sequence update: January 23, 2007
Last modified: November 26, 2014
This is version 88 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3