Reviewed,
UniProtKB/Swiss-Prot P62273 (RS29_HUMAN)
Last modified
June 16, 2009.
Version 48.
History...
Clusters with 100%,
90%,
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: 40S ribosomal protein S29 | ||
| Gene names |
| ||
| Organism | Homo sapiens (Human) | ||
| Taxonomic identifier | 9606 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Protein attributes
| Sequence length | 56 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Cofactor | Binds 1 zinc ion per subunit Potential. |
| Sequence similarities | Belongs to the ribosomal protein S14P family. |
Ontologies
| Keywords | |
|---|---|
| Ligand | Metal-binding Zinc |
| Molecular function | Ribonucleoprotein Ribosomal protein |
| Technical term | Direct protein sequencing |
| Gene Ontology (GO) | |
| Biological process | translational elongation Inferred from Experiment. Source: Reactome |
| Cellular component | cytosolic small ribosomal subunit Ref.5 Inferred from direct assay. Source: UniProtKB |
| Molecular function | protein binding Inferred from physical interaction. Source: IntAct structural constituent of ribosomeInferred from direct assay. Source: UniProtKB zinc ion binding Ref.2Inferred from direct assay. Source: UniProtKB |
| Complete GO annotation... | |
Binary interactions
With | Entry | #Exp. | IntAct | Notes |
|---|---|---|---|---|
| DDX56 | Q9NY93 | 1 | EBI-1054121,EBI-372376 | |
| EIF1B | O60739 | 1 | EBI-1054121,EBI-1043343 | |
| EIF4A2 | Q14240 | 1 | EBI-1054121,EBI-73473 | |
| EXT2 | Q93063 | 1 | EBI-1054121,EBI-1047761 | |
| STYXL1 | Q9Y6J8 | 1 | EBI-1054121,EBI-1044511 |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Initiator methionine | 1 | 1 | Removed Ref.5 Ref.6 | ||||||
| Chain | 2 – 56 | 55 | 40S ribosomal protein S29 | PRO_0000131019 | |||||
Sites | |||||||||
| Metal binding | 21 | 1 | Zinc Potential | ||||||
| Metal binding | 24 | 1 | Zinc Potential | ||||||
| Metal binding | 39 | 1 | Zinc Potential | ||||||
| Metal binding | 42 | 1 | Zinc Potential | ||||||
Sequences
References
| « Hide 'large scale' references | |
| [1] | "Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs." Frigerio J.-M., Dagorn J.-C., Iovanna J.L. Biochim. Biophys. Acta 1262:64-68(1995) [PubMed: 7772601] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Colon. |
| [2] | "The S29 ribosomal protein increases tumor suppressor activity of K rev-1 gene on v-K ras-transformed NIH3T3 cells." Kondoh N., Noda M., Fisher R.J., Schweinfest C.W., Papas T.S., Kondoh A., Samuel K.P., Oikawa T. Biochim. Biophys. Acta 1313:41-46(1996) [PubMed: 8781548] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Colon. |
| [3] | "The human ribosomal protein genes: sequencing and comparative analysis of 73 genes." Yoshihama M., Uechi T., Asakawa S., Kawasaki K., Kato S., Higa S., Maeda N., Minoshima S., Tanaka T., Shimizu N., Kenmochi N. Genome Res. 12:379-390(2002) [PubMed: 11875025] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| [4] | "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Blood and Eye. |
| [5] | "Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry." Vladimirov S.N., Ivanov A.V., Karpova G.G., Musolyamov A.K., Egorov T.A., Thiede B., Wittmann-Liebold B., Otto A. Eur. J. Biochem. 239:144-149(1996) [PubMed: 8706699] [Abstract] Cited for: PROTEIN SEQUENCE OF 2-11. Tissue: Placenta. |
| [6] | Bienvenut W.V., Murray L., Brunton V.G., Frame M.C. Submitted (FEB-2008) to UniProtKB Cited for: PROTEIN SEQUENCE OF 2-12 AND 49-56, CLEAVAGE OF INITIATOR METHIONINE, MASS SPECTROMETRY. Tissue: Colon adenocarcinoma. |
| [7] | "A map of 75 human ribosomal protein genes." Kenmochi N., Kawaguchi T., Rozen S., Davis E., Goodman N., Hudson T.J., Tanaka T., Page D.C. Genome Res. 8:509-523(1998) [PubMed: 9582194] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 29-54. |
| [8] | Colinge J., Superti-Furga G., Bennett K.L. Submitted (OCT-2008) to UniProtKB Cited for: IDENTIFICATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| U14973 mRNA. Translation: AAA85661.1. L31610 mRNA. Translation: AAB27426.1. AB061847 Genomic DNA. Translation: BAB79485.1. BC032813 mRNA. Translation: AAH32813.1. BC035313 mRNA. Translation: AAH35313.1. AB007165 Genomic DNA. Translation: BAA25827.1. | |
| IPI | IPI00182289. |
| PIR | S55919. |
| RefSeq | NP_001023.1. |
| UniGene | Hs.156367 |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| IntAct | P62273. 10 interactions. |
Proteomic databases | |
| PRIDE | P62273. |
Genome annotation databases | |
| Ensembl | ENSG00000213741. Homo sapiens. [Contig view] |
| GeneID | 6235. |
Organism-specific databases | |
| GeneCards | GC03P197747. GC04P025289. GC07P102776. GC14M049119. GC14M049121. |
| HGNC | HGNC:10419. RPS29. |
| HPA | HPA004107. |
| MIM | 603633. gene. |
| PharmGKB | PA34826. |
| GenAtlas | Search... |
Phylogenomic databases | |
| HOVERGEN | P62273. |
Enzyme and pathway databases | |
| Reactome | REACT_1762. 3' -UTR-mediated translational regulation. REACT_6167. Influenza Infection. REACT_71. Gene Expression. |
Gene expression databases | |
| ArrayExpress | P62273. |
| Bgee | P62273. |
| CleanEx | HS_RPS29. |
| GermOnline | ENSG00000125385. Homo sapiens. |
Family and domain databases | |
| InterPro | IPR001209. Ribosomal_S14. IPR018271. Ribosomal_S14_CS. [Graphical view] |
| Pfam | PF00253. Ribosomal_S14. 1 hit. [Graphical view] |
| PROSITE | PS00527. RIBOSOMAL_S14. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other Resources | |
| NextBio | 24205. |
| SOURCE | Search... |
Entry information
| Entry name | RS29_HUMAN | ||||||||
| Accession | Primary (citable) accession number: P62273 Secondary accession number(s): P30054 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HPI (Human Proteome Initiative) | ||||||||
Relevant documents
| Human chromosome 14 Human chromosome 14: entries, gene names and cross-references to MIM |
| MIM cross-references Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot |
| Ribosomal proteins Ribosomal proteins families and list of entries |
| SIMILARITY comments Index of protein domains and families |
