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Protein

40S ribosomal protein S18

Gene

RPS18

Organism
Sus scrofa (Pig)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Enzyme and pathway databases

ReactomeiR-SSC-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-SSC-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-SSC-72702. Ribosomal scanning and start codon recognition.
R-SSC-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-SSC-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S18
Gene namesi
Name:RPS18
OrganismiSus scrofa (Pig)
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Chromosome 7

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 15215140S ribosomal protein S18PRO_0000132214Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylserineBy similarity
Modified residuei94 – 941N6-acetyllysineBy similarity
Modified residuei106 – 1061N6-acetyllysineBy similarity

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiP62272.
PeptideAtlasiP62272.
PRIDEiP62272.

Expressioni

Gene expression databases

GenevisibleiP62272. SS.

Interactioni

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000001631.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3J7Pelectron microscopy3.50SS1-152[»]
3J7Relectron microscopy3.90SS1-152[»]
ProteinModelPortaliP62272.
SMRiP62272. Positions 3-145.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S13P family.Curated

Phylogenomic databases

eggNOGiKOG3311. Eukaryota.
COG0099. LUCA.
GeneTreeiENSGT00390000012691.
HOGENOMiHOG000039877.
HOVERGENiHBG000200.
InParanoidiP62272.
KOiK02964.
OMAiRIMNTDL.
OrthoDBiEOG7Q5HG2.
TreeFamiTF317649.

Family and domain databases

Gene3Di4.10.910.10. 1 hit.
HAMAPiMF_01315. Ribosomal_S13_S18.
InterProiIPR027437. 30s_Rbsml_prot_S13_C.
IPR001892. Ribosomal_S13.
IPR010979. Ribosomal_S13-like_H2TH.
IPR018269. Ribosomal_S13_CS.
[Graphical view]
PfamiPF00416. Ribosomal_S13. 1 hit.
[Graphical view]
PIRSFiPIRSF002134. Ribosomal_S13. 1 hit.
SUPFAMiSSF46946. SSF46946. 1 hit.
PROSITEiPS00646. RIBOSOMAL_S13_1. 1 hit.
PS50159. RIBOSOMAL_S13_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P62272-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLVIPEKFQ HILRVLNTNI DGRRKIAFAI TAIKGVGRRY AHVVLRKADI
60 70 80 90 100
DLTKRAGELT EDEVERVITI MQNPRQYKIP DWFLNRQKDV KDGKYSQVLA
110 120 130 140 150
NGLDNKLRED LERLKKIRAH RGLRHFWGLR VRGQHTKTTG RRGRTVGVSK

KK
Length:152
Mass (Da):17,719
Last modified:January 23, 2007 - v3
Checksum:i4DAF0662C3F37F22
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB000911 mRNA. Translation: BAA19211.1.
RefSeqiNP_999105.1. NM_213940.1.
UniGeneiSsc.53782.

Genome annotation databases

EnsembliENSSSCT00000001675; ENSSSCP00000001631; ENSSSCG00000001502.
GeneIDi396980.
KEGGissc:396980.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB000911 mRNA. Translation: BAA19211.1.
RefSeqiNP_999105.1. NM_213940.1.
UniGeneiSsc.53782.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3J7Pelectron microscopy3.50SS1-152[»]
3J7Relectron microscopy3.90SS1-152[»]
ProteinModelPortaliP62272.
SMRiP62272. Positions 3-145.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000001631.

Proteomic databases

PaxDbiP62272.
PeptideAtlasiP62272.
PRIDEiP62272.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSSSCT00000001675; ENSSSCP00000001631; ENSSSCG00000001502.
GeneIDi396980.
KEGGissc:396980.

Organism-specific databases

CTDi6222.

Phylogenomic databases

eggNOGiKOG3311. Eukaryota.
COG0099. LUCA.
GeneTreeiENSGT00390000012691.
HOGENOMiHOG000039877.
HOVERGENiHBG000200.
InParanoidiP62272.
KOiK02964.
OMAiRIMNTDL.
OrthoDBiEOG7Q5HG2.
TreeFamiTF317649.

Enzyme and pathway databases

ReactomeiR-SSC-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-SSC-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-SSC-72702. Ribosomal scanning and start codon recognition.
R-SSC-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-SSC-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Gene expression databases

GenevisibleiP62272. SS.

Family and domain databases

Gene3Di4.10.910.10. 1 hit.
HAMAPiMF_01315. Ribosomal_S13_S18.
InterProiIPR027437. 30s_Rbsml_prot_S13_C.
IPR001892. Ribosomal_S13.
IPR010979. Ribosomal_S13-like_H2TH.
IPR018269. Ribosomal_S13_CS.
[Graphical view]
PfamiPF00416. Ribosomal_S13. 1 hit.
[Graphical view]
PIRSFiPIRSF002134. Ribosomal_S13. 1 hit.
SUPFAMiSSF46946. SSF46946. 1 hit.
PROSITEiPS00646. RIBOSOMAL_S13_1. 1 hit.
PS50159. RIBOSOMAL_S13_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Cloning of the pig homolog of bacterial ribosomal protein S13."
    Kimura M., Kawakami K., Suzuki H., Hamasima N.
    Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiRS18_PIG
AccessioniPrimary (citable) accession number: P62272
Secondary accession number(s): P25232
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: January 23, 2007
Last modified: July 6, 2016
This is version 82 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.