Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P62270 (RS18_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
40S ribosomal protein S18
Alternative name(s):
Ke-3
Short name=Ke3
Gene names
Name:Rps18
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length152 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA By similarity. HAMAP-Rule MF_01315

Subcellular location

Cytoplasm HAMAP-Rule MF_01315.

Sequence similarities

Belongs to the ribosomal protein S13P family.

Binary interactions

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 15215140S ribosomal protein S18 HAMAP-Rule MF_01315
PRO_0000132213

Amino acid modifications

Modified residue21N-acetylserine By similarity
Modified residue941N6-acetyllysine By similarity
Modified residue1061N6-acetyllysine By similarity

Experimental info

Sequence conflict1041D → H in AAA16796. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P62270 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: 4DAF0662C3F37F22

FASTA15217,719
        10         20         30         40         50         60 
MSLVIPEKFQ HILRVLNTNI DGRRKIAFAI TAIKGVGRRY AHVVLRKADI DLTKRAGELT 

        70         80         90        100        110        120 
EDEVERVITI MQNPRQYKIP DWFLNRQKDV KDGKYSQVLA NGLDNKLRED LERLKKIRAH 

       130        140        150 
RGLRHFWGLR VRGQHTKTTG RRGRTVGVSK KK 

« Hide

References

« Hide 'large scale' references
[1]"The murine MHC encodes a mammalian homolog of bacterial ribosomal protein S13."
Macmurray A.J., Shin H.S.
Mamm. Genome 2:87-95(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"Sequence of the mouse major histocomaptibility locus class II region."
Rowen L., Qin S., Madan A., Loretz C., James R., Dors M., Mix L., Hall J., Lasky S., Hood L.
Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 129/SvJ.
[3]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Thymus.
[4]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6.
Tissue: Brain.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M76763 mRNA. Translation: AAA16795.1.
M76762 Unassigned DNA. Translation: AAA16796.1.
AF100956 Genomic DNA. Translation: AAC69898.1.
AF110520 Genomic DNA. Translation: AAC97978.1.
AK050626 mRNA. Translation: BAC34350.1.
BC081459 mRNA. Translation: AAH81459.1.
BC081458 mRNA. Translation: AAH81458.1.
PIRI76666.
RefSeqNP_035426.1. NM_011296.2.
UniGeneMm.298745.
Mm.324762.
Mm.440079.

3D structure databases

ProteinModelPortalP62270.
SMRP62270. Positions 13-152.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP62270. 5 interactions.
MINTMINT-1865215.

PTM databases

PhosphoSiteP62270.

Proteomic databases

PaxDbP62270.
PRIDEP62270.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000008812; ENSMUSP00000008812; ENSMUSG00000008668.
GeneID20084.
KEGGmmu:20084.
UCSCuc008cak.1. mouse.

Organism-specific databases

CTD6222.
MGIMGI:98146. Rps18.

Phylogenomic databases

eggNOGCOG0099.
HOGENOMHOG000039877.
HOVERGENHBG000200.
InParanoidP62270.
KOK02964.
OMAIRAYRGI.
OrthoDBEOG7Q5HG2.
PhylomeDBP62270.
TreeFamTF317649.

Gene expression databases

BgeeP62270.
CleanExMM_RPS18.
GenevestigatorP62270.

Family and domain databases

Gene3D4.10.910.10. 1 hit.
HAMAPMF_01315. Ribosomal_S13_S18.
InterProIPR027437. 30s_Rbsml_prot_S13_C.
IPR001892. Ribosomal_S13.
IPR010979. Ribosomal_S13-like_H2TH.
IPR018269. Ribosomal_S13_CS.
[Graphical view]
PfamPF00416. Ribosomal_S13. 1 hit.
[Graphical view]
PIRSFPIRSF002134. Ribosomal_S13. 1 hit.
SUPFAMSSF46946. SSF46946. 1 hit.
PROSITEPS00646. RIBOSOMAL_S13_1. 1 hit.
PS50159. RIBOSOMAL_S13_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio24155.
PROP62270.
SOURCESearch...

Entry information

Entry nameRS18_MOUSE
AccessionPrimary (citable) accession number: P62270
Secondary accession number(s): P25232
Entry history
Integrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: January 23, 2007
Last modified: April 16, 2014
This is version 85 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot