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Protein

40S ribosomal protein S15a

Gene

Rps15a

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-RNO-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-RNO-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-RNO-6791226. Major pathway of rRNA processing in the nucleolus.
R-RNO-72649. Translation initiation complex formation.
R-RNO-72689. Formation of a pool of free 40S subunits.
R-RNO-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-RNO-72702. Ribosomal scanning and start codon recognition.
R-RNO-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-RNO-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-RNO-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S15a
Gene namesi
Name:Rps15a
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi619939. Rps15a.

Subcellular locationi

GO - Cellular componenti

  • cytosolic small ribosomal subunit Source: RGD
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemoved1 Publication
Chaini2 – 13012940S ribosomal protein S15aPRO_0000126604Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei88 – 881N6-succinyllysineBy similarity

Proteomic databases

PaxDbiP62246.
PRIDEiP62246.

Expressioni

Gene expression databases

GenevisibleiP62246. RN.

Interactioni

Protein-protein interaction databases

BioGridi250650. 1 interaction.
IntActiP62246. 2 interactions.
MINTiMINT-4577018.
STRINGi10116.ENSRNOP00000024678.

Structurei

3D structure databases

ProteinModelPortaliP62246.
SMRiP62246. Positions 2-130.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S8P family.Curated

Phylogenomic databases

eggNOGiKOG1754. Eukaryota.
COG0096. LUCA.
GeneTreeiENSGT00390000003021.
HOGENOMiHOG000204097.
HOVERGENiHBG056618.
InParanoidiP62246.
KOiK02957.
OMAiTHEVTPA.
OrthoDBiEOG77Q4ZM.
PhylomeDBiP62246.
TreeFamiTF300067.

Family and domain databases

HAMAPiMF_01302_A. Ribosomal_S8_A.
InterProiIPR000630. Ribosomal_S8.
[Graphical view]
PANTHERiPTHR11758. PTHR11758. 1 hit.
PfamiPF00410. Ribosomal_S8. 1 hit.
[Graphical view]
SUPFAMiSSF56047. SSF56047. 1 hit.
PROSITEiPS00053. RIBOSOMAL_S8. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P62246-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRMNVLADA LKSINNAEKR GKRQVLIRPC SKVIVRFLTV MMKHGYIGEF
60 70 80 90 100
EIIDDHRAGK IVVNLTGRLN KCGVISPRFD VQLKDLEKWQ NNLLPSRQFG
110 120 130
FIVLTTSAGI MDHEEARRKH TGGKILGFFF
Length:130
Mass (Da):14,840
Last modified:January 23, 2007 - v2
Checksum:iD4AC1E8864E3A184
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X77953 mRNA. Translation: CAA54918.1.
BC058452 mRNA. Translation: AAH58452.1.
PIRiJC2234.
RefSeqiNP_446434.1. NM_053982.1.
XP_006230159.1. XM_006230097.1.
XP_006230160.1. XM_006230098.1.
UniGeneiRn.2890.

Genome annotation databases

EnsembliENSRNOT00000024678; ENSRNOP00000024678; ENSRNOG00000018320.
ENSRNOT00000092282; ENSRNOP00000075906; ENSRNOG00000018320.
ENSRNOT00000092513; ENSRNOP00000075747; ENSRNOG00000018320.
GeneIDi117053.
KEGGirno:117053.
UCSCiRGD:619939. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X77953 mRNA. Translation: CAA54918.1.
BC058452 mRNA. Translation: AAH58452.1.
PIRiJC2234.
RefSeqiNP_446434.1. NM_053982.1.
XP_006230159.1. XM_006230097.1.
XP_006230160.1. XM_006230098.1.
UniGeneiRn.2890.

3D structure databases

ProteinModelPortaliP62246.
SMRiP62246. Positions 2-130.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi250650. 1 interaction.
IntActiP62246. 2 interactions.
MINTiMINT-4577018.
STRINGi10116.ENSRNOP00000024678.

Proteomic databases

PaxDbiP62246.
PRIDEiP62246.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000024678; ENSRNOP00000024678; ENSRNOG00000018320.
ENSRNOT00000092282; ENSRNOP00000075906; ENSRNOG00000018320.
ENSRNOT00000092513; ENSRNOP00000075747; ENSRNOG00000018320.
GeneIDi117053.
KEGGirno:117053.
UCSCiRGD:619939. rat.

Organism-specific databases

CTDi6210.
RGDi619939. Rps15a.

Phylogenomic databases

eggNOGiKOG1754. Eukaryota.
COG0096. LUCA.
GeneTreeiENSGT00390000003021.
HOGENOMiHOG000204097.
HOVERGENiHBG056618.
InParanoidiP62246.
KOiK02957.
OMAiTHEVTPA.
OrthoDBiEOG77Q4ZM.
PhylomeDBiP62246.
TreeFamiTF300067.

Enzyme and pathway databases

ReactomeiR-RNO-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-RNO-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-RNO-6791226. Major pathway of rRNA processing in the nucleolus.
R-RNO-72649. Translation initiation complex formation.
R-RNO-72689. Formation of a pool of free 40S subunits.
R-RNO-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-RNO-72702. Ribosomal scanning and start codon recognition.
R-RNO-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-RNO-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-RNO-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

PROiP62246.

Gene expression databases

GenevisibleiP62246. RN.

Family and domain databases

HAMAPiMF_01302_A. Ribosomal_S8_A.
InterProiIPR000630. Ribosomal_S8.
[Graphical view]
PANTHERiPTHR11758. PTHR11758. 1 hit.
PfamiPF00410. Ribosomal_S8. 1 hit.
[Graphical view]
SUPFAMiSSF56047. SSF56047. 1 hit.
PROSITEiPS00053. RIBOSOMAL_S8. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 2-38.
    Strain: Sprague-Dawley.
    Tissue: Liver.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Pituitary.

Entry informationi

Entry nameiRS15A_RAT
AccessioniPrimary (citable) accession number: P62246
Secondary accession number(s): P39027
, P39031, Q8C023, Q9BV24
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: January 23, 2007
Last modified: June 8, 2016
This is version 90 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.