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P62082

- RS7_MOUSE

UniProt

P62082 - RS7_MOUSE

Protein

40S ribosomal protein S7

Gene

Rps7

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 1 (21 Jun 2004)
      Previous versions | rss
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    Functioni

    Required for rRNA maturation.By similarity

    GO - Molecular functioni

    1. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. cell differentiation Source: MGI
    2. cytoplasmic translation Source: RefGenome
    3. neural tube closure Source: MGI
    4. ribosomal small subunit biogenesis Source: RefGenome
    5. rRNA processing Source: RefGenome

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    40S ribosomal protein S7
    Gene namesi
    Name:Rps7
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 12

    Organism-specific databases

    MGIiMGI:1333818. Rps7.

    Subcellular locationi

    Cytoplasmcytoskeletonmicrotubule organizing centercentrosome By similarity
    Note: Colocalizes with NEK6 in the centrosome.By similarity

    GO - Cellular componenti

    1. 90S preribosome Source: RefGenome
    2. cytosolic small ribosomal subunit Source: RefGenome
    3. microtubule organizing center Source: UniProtKB-SubCell
    4. ribonucleoprotein complex Source: MGI
    5. small-subunit processome Source: RefGenome

    Keywords - Cellular componenti

    Cytoplasm, Cytoskeleton

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 19419440S ribosomal protein S7PRO_0000174191Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei1 – 11N-acetylmethionineBy similarity
    Modified residuei74 – 741N6-acetyllysineBy similarity

    Post-translational modificationi

    Phosphorylated by NEK6.By similarity

    Keywords - PTMi

    Acetylation

    Proteomic databases

    MaxQBiP62082.
    PaxDbiP62082.
    PRIDEiP62082.

    PTM databases

    PhosphoSiteiP62082.

    Expressioni

    Gene expression databases

    ArrayExpressiP62082.
    BgeeiP62082.
    CleanExiMM_RPS7.
    GenevestigatoriP62082.

    Interactioni

    Subunit structurei

    Binds IPO9 with high affinity. Interacts with NEK6.By similarity

    Protein-protein interaction databases

    BioGridi203016. 5 interactions.
    IntActiP62082. 8 interactions.
    MINTiMINT-1857682.
    STRINGi10090.ENSMUSP00000073880.

    Structurei

    3D structure databases

    ProteinModelPortaliP62082.
    SMRiP62082. Positions 5-194.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi98 – 12023Arg/Lys-rich (basic)Add
    BLAST

    Sequence similaritiesi

    Belongs to the ribosomal protein S7e family.Curated

    Phylogenomic databases

    eggNOGiNOG280542.
    HOGENOMiHOG000197237.
    HOVERGENiHBG001698.
    InParanoidiP62082.
    KOiK02993.
    OMAiIEVGHGK.
    OrthoDBiEOG74J997.
    PhylomeDBiP62082.
    TreeFamiTF343364.

    Family and domain databases

    InterProiIPR000554. Ribosomal_S7e.
    [Graphical view]
    PANTHERiPTHR11278. PTHR11278. 1 hit.
    PfamiPF01251. Ribosomal_S7e. 1 hit.
    [Graphical view]
    PROSITEiPS00948. RIBOSOMAL_S7E. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P62082-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFSSSAKIVK PNGEKPDEFE SGISQALLEL EMNSDLKAQL RELNITAAKE    50
    IEVGGGRKAI IIFVPVPQLK SFQKIQVRLV RELEKKFSGK HVVFIAQRRI 100
    LPKPTRKSRT KNKQKRPRSR TLTAVHDAIL EDLVFPSEIV GKRIRVKLDG 150
    SRLIKVHLDK AQQNNVEHKV ETFSGVYKKL TGKDVNFEFP EFQL 194
    Length:194
    Mass (Da):22,127
    Last modified:June 21, 2004 - v1
    Checksum:iE21089929CC061E9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF043285 Genomic DNA. Translation: AAB97861.1.
    BC002014 mRNA. Translation: AAH02014.1.
    CCDSiCCDS25851.1.
    RefSeqiNP_035430.1. NM_011300.3.
    UniGeneiMm.279839.
    Mm.371579.

    Genome annotation databases

    EnsembliENSMUST00000074267; ENSMUSP00000073880; ENSMUSG00000061477.
    GeneIDi20115.
    KEGGimmu:20115.
    UCSCiuc007nfs.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF043285 Genomic DNA. Translation: AAB97861.1 .
    BC002014 mRNA. Translation: AAH02014.1 .
    CCDSi CCDS25851.1.
    RefSeqi NP_035430.1. NM_011300.3.
    UniGenei Mm.279839.
    Mm.371579.

    3D structure databases

    ProteinModelPortali P62082.
    SMRi P62082. Positions 5-194.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 203016. 5 interactions.
    IntActi P62082. 8 interactions.
    MINTi MINT-1857682.
    STRINGi 10090.ENSMUSP00000073880.

    PTM databases

    PhosphoSitei P62082.

    Proteomic databases

    MaxQBi P62082.
    PaxDbi P62082.
    PRIDEi P62082.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000074267 ; ENSMUSP00000073880 ; ENSMUSG00000061477 .
    GeneIDi 20115.
    KEGGi mmu:20115.
    UCSCi uc007nfs.2. mouse.

    Organism-specific databases

    CTDi 6201.
    MGIi MGI:1333818. Rps7.

    Phylogenomic databases

    eggNOGi NOG280542.
    HOGENOMi HOG000197237.
    HOVERGENi HBG001698.
    InParanoidi P62082.
    KOi K02993.
    OMAi IEVGHGK.
    OrthoDBi EOG74J997.
    PhylomeDBi P62082.
    TreeFami TF343364.

    Miscellaneous databases

    NextBioi 24083.
    PROi P62082.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi P62082.
    Bgeei P62082.
    CleanExi MM_RPS7.
    Genevestigatori P62082.

    Family and domain databases

    InterProi IPR000554. Ribosomal_S7e.
    [Graphical view ]
    PANTHERi PTHR11278. PTHR11278. 1 hit.
    Pfami PF01251. Ribosomal_S7e. 1 hit.
    [Graphical view ]
    PROSITEi PS00948. RIBOSOMAL_S7E. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Isolation and characterization of the mouse ribosomal protein S7 gene."
      Annilo T., Jelina J., Pata I., Metspalu A.
      Biochem. Mol. Biol. Int. 46:287-295(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: 129/Sv.
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Mammary tumor.

    Entry informationi

    Entry nameiRS7_MOUSE
    AccessioniPrimary (citable) accession number: P62082
    Secondary accession number(s): P23821, P24818
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 21, 2004
    Last sequence update: June 21, 2004
    Last modified: October 1, 2014
    This is version 81 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3