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P62082

- RS7_MOUSE

UniProt

P62082 - RS7_MOUSE

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Protein

40S ribosomal protein S7

Gene
Rps7
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Required for rRNA maturation By similarity.

GO - Molecular functioni

  1. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. cell differentiation Source: MGI
  2. cytoplasmic translation Source: RefGenome
  3. neural tube closure Source: MGI
  4. ribosomal small subunit biogenesis Source: RefGenome
  5. rRNA processing Source: RefGenome
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S7
Gene namesi
Name:Rps7
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 12

Organism-specific databases

MGIiMGI:1333818. Rps7.

Subcellular locationi

Cytoplasmcytoskeletonmicrotubule organizing centercentrosome By similarity
Note: Colocalizes with NEK6 in the centrosome By similarity.

GO - Cellular componenti

  1. 90S preribosome Source: RefGenome
  2. cytosolic small ribosomal subunit Source: RefGenome
  3. microtubule organizing center Source: UniProtKB-SubCell
  4. ribonucleoprotein complex Source: MGI
  5. small-subunit processome Source: RefGenome
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 19419440S ribosomal protein S7PRO_0000174191Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylmethionine By similarity
Modified residuei74 – 741N6-acetyllysine By similarity

Post-translational modificationi

Phosphorylated by NEK6 By similarity.

Keywords - PTMi

Acetylation

Proteomic databases

MaxQBiP62082.
PaxDbiP62082.
PRIDEiP62082.

PTM databases

PhosphoSiteiP62082.

Expressioni

Gene expression databases

ArrayExpressiP62082.
BgeeiP62082.
CleanExiMM_RPS7.
GenevestigatoriP62082.

Interactioni

Subunit structurei

Binds IPO9 with high affinity By similarity. Interacts with NEK6 By similarity.

Protein-protein interaction databases

BioGridi203016. 5 interactions.
IntActiP62082. 8 interactions.
MINTiMINT-1857682.
STRINGi10090.ENSMUSP00000073880.

Structurei

3D structure databases

ProteinModelPortaliP62082.
SMRiP62082. Positions 5-194.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi98 – 12023Arg/Lys-rich (basic)Add
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiNOG280542.
HOGENOMiHOG000197237.
HOVERGENiHBG001698.
InParanoidiP62082.
KOiK02993.
OMAiIEVGHGK.
OrthoDBiEOG74J997.
PhylomeDBiP62082.
TreeFamiTF343364.

Family and domain databases

InterProiIPR000554. Ribosomal_S7e.
[Graphical view]
PANTHERiPTHR11278. PTHR11278. 1 hit.
PfamiPF01251. Ribosomal_S7e. 1 hit.
[Graphical view]
PROSITEiPS00948. RIBOSOMAL_S7E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P62082-1 [UniParc]FASTAAdd to Basket

« Hide

MFSSSAKIVK PNGEKPDEFE SGISQALLEL EMNSDLKAQL RELNITAAKE    50
IEVGGGRKAI IIFVPVPQLK SFQKIQVRLV RELEKKFSGK HVVFIAQRRI 100
LPKPTRKSRT KNKQKRPRSR TLTAVHDAIL EDLVFPSEIV GKRIRVKLDG 150
SRLIKVHLDK AQQNNVEHKV ETFSGVYKKL TGKDVNFEFP EFQL 194
Length:194
Mass (Da):22,127
Last modified:June 21, 2004 - v1
Checksum:iE21089929CC061E9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF043285 Genomic DNA. Translation: AAB97861.1.
BC002014 mRNA. Translation: AAH02014.1.
CCDSiCCDS25851.1.
RefSeqiNP_035430.1. NM_011300.3.
UniGeneiMm.279839.
Mm.371579.

Genome annotation databases

EnsembliENSMUST00000074267; ENSMUSP00000073880; ENSMUSG00000061477.
GeneIDi20115.
KEGGimmu:20115.
UCSCiuc007nfs.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF043285 Genomic DNA. Translation: AAB97861.1 .
BC002014 mRNA. Translation: AAH02014.1 .
CCDSi CCDS25851.1.
RefSeqi NP_035430.1. NM_011300.3.
UniGenei Mm.279839.
Mm.371579.

3D structure databases

ProteinModelPortali P62082.
SMRi P62082. Positions 5-194.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 203016. 5 interactions.
IntActi P62082. 8 interactions.
MINTi MINT-1857682.
STRINGi 10090.ENSMUSP00000073880.

PTM databases

PhosphoSitei P62082.

Proteomic databases

MaxQBi P62082.
PaxDbi P62082.
PRIDEi P62082.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000074267 ; ENSMUSP00000073880 ; ENSMUSG00000061477 .
GeneIDi 20115.
KEGGi mmu:20115.
UCSCi uc007nfs.2. mouse.

Organism-specific databases

CTDi 6201.
MGIi MGI:1333818. Rps7.

Phylogenomic databases

eggNOGi NOG280542.
HOGENOMi HOG000197237.
HOVERGENi HBG001698.
InParanoidi P62082.
KOi K02993.
OMAi IEVGHGK.
OrthoDBi EOG74J997.
PhylomeDBi P62082.
TreeFami TF343364.

Miscellaneous databases

NextBioi 24083.
PROi P62082.
SOURCEi Search...

Gene expression databases

ArrayExpressi P62082.
Bgeei P62082.
CleanExi MM_RPS7.
Genevestigatori P62082.

Family and domain databases

InterProi IPR000554. Ribosomal_S7e.
[Graphical view ]
PANTHERi PTHR11278. PTHR11278. 1 hit.
Pfami PF01251. Ribosomal_S7e. 1 hit.
[Graphical view ]
PROSITEi PS00948. RIBOSOMAL_S7E. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Isolation and characterization of the mouse ribosomal protein S7 gene."
    Annilo T., Jelina J., Pata I., Metspalu A.
    Biochem. Mol. Biol. Int. 46:287-295(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 129/Sv.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Mammary tumor.

Entry informationi

Entry nameiRS7_MOUSE
AccessioniPrimary (citable) accession number: P62082
Secondary accession number(s): P23821, P24818
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 21, 2004
Last sequence update: June 21, 2004
Last modified: September 3, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi