P62014 (RPOK_PYRAB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA-directed RNA polymerase subunit K
EC=2.7.7.6

Gene names

Name:	rpoK
Ordered Locus Names:	PYRAB05350
ORF Names:	PAB7132

Organism

Pyrococcus abyssi (strain GE5 / Orsay) [Complete proteome] [HAMAP]

Taxonomic identifier

272844 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	57 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. HAMAP MF_00192
Catalytic activity	Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP MF_00192
Sequence similarities	Belongs to the archaeal rpoK/eukaryotic RPB6 RNA polymerase subunit family.

Ontologies

Keywords
Biological process	Transcription
Cellular component	DNA-directed RNA polymerase
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	RNA polymerase complex Inferred from electronic annotation. Source: InterPro
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 57	57	DNA-directed RNA polymerase subunit K HAMAP MF_00192		PRO_0000133817

Sequences

	Sequence		Length	Mass (Da)
	P62014 [UniParc]. Last modified June 7, 2004. Version 1. Checksum: 8E945FCC29A80968	FASTA	57	6,271
	10 20 30 40 50 MFKYTRFEKA RIIGARALQI AMGAPVLIDV PEGITPLEAA IMEFEKGVIP ITVIRPS

References

[1]

"An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi." Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O., Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P. Mol. Microbiol. 47:1495-1512(2003) [PubMed: 12622808] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GE5 / Orsay.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ248284 Genomic DNA. Translation: CAB49457.1.
PIR	B75172.
RefSeq	NP_126226.1. NC_000868.1.
3D structure databases
ProteinModelPortal	P62014.
SMR	P62014. Positions 3-55.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBPYRT00000002488; EBPYRP00000002419; EBPYRG00000002488.
GeneID	1495437.
GenomeReviews	Gene locus PYRAB05350 in contig AL096836_GR.
KEGG	pab:PAB7132.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000022807.
HOGENOM	HBG646526.
OMA	FRYTRFE.
ProtClustDB	PRK01099.
Enzyme and pathway databases
BioCyc	PABY272844:PAB7132-MONOMER.
Family and domain databases
HAMAP	MF_00192. RNApol_arch_K. [Tree]
InterPro	IPR020708. DNA-dir_RNA_polK_14-18kDa_CS. IPR006111. DNA-dir_RNA_polK_K/RPABC2. IPR006110. RNA_poly_omega/K/RPABC2. IPR012293. RNAP_RPB6_omega. [Graphical view]
Gene3D	G3DSA:3.90.940.10. RNAP_RPB6_omega. 1 hit.
KO	K03055.
PANTHER	PTHR10773. RNA_polK_14kDa. 1 hit.
Pfam	PF01192. RNA_pol_Rpb6. 1 hit. [Graphical view]
PIRSF	PIRSF000778. RpoK/RPB6. 1 hit.
SUPFAM	SSF63562. RNA_pol_omega. 1 hit.
PROSITE	PS01111. RNA_POL_K_14KD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RPOK_PYRAB

Accession

Primary (citable) accession number: P62014
Secondary accession number(s): Q9V193

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 7, 2004
Last sequence update:	June 7, 2004
Last modified:	November 16, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program