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Protein

50S ribosomal protein L7Ae

Gene

rpl7ae

Organism
Pyrococcus abyssi (strain GE5 / Orsay)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L7AeUniRule annotation
Alternative name(s):
Ribosomal protein L8eUniRule annotation
Gene namesi
Name:rpl7aeUniRule annotation
Ordered Locus Names:PYRAB06750
ORF Names:PAB0460
OrganismiPyrococcus abyssi (strain GE5 / Orsay)
Taxonomic identifieri272844 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000000810 Componenti: Chromosome
  • UP000009139 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001368001 – 12350S ribosomal protein L7AeAdd BLAST123

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Probably part of the RNase P complex.UniRule annotation

Protein-protein interaction databases

STRINGi272844.PAB0460.

Structurei

Secondary structure

1123
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi13 – 29Combined sources17
Beta strandi30 – 35Combined sources6
Helixi36 – 44Combined sources9
Beta strandi49 – 55Combined sources7
Helixi60 – 62Combined sources3
Turni63 – 65Combined sources3
Helixi66 – 72Combined sources7
Beta strandi77 – 81Combined sources5
Helixi83 – 89Combined sources7
Beta strandi97 – 103Combined sources7
Helixi105 – 107Combined sources3
Helixi108 – 121Combined sources14

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1PXWX-ray1.94A/B1-123[»]
ProteinModelPortaliP62008.
SMRiP62008.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP62008.

Family & Domainsi

Sequence similaritiesi

Belongs to the eukaryotic ribosomal protein eL8 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01751. Archaea.
COG1358. LUCA.
HOGENOMiHOG000055225.
KOiK02936.
OMAiKPFYVRF.
OrthoDBiPOG093Z0LB6.

Family and domain databases

Gene3Di3.30.1330.30. 1 hit.
HAMAPiMF_00326. Ribosomal_L7Ae_Arch. 1 hit.
InterProiView protein in InterPro
IPR029064. L30e-like.
IPR004038. Ribosomal_L7Ae/L30e/S12e/Gad45.
IPR018492. Ribosomal_L7Ae/L8/Nhp2.
IPR022481. Ribosomal_L7Ae_arc.
IPR004037. Ribosomal_L7Ae_CS.
IPR000948. Ribosomal_L7Ae_prok.
PfamiView protein in Pfam
PF01248. Ribosomal_L7Ae. 1 hit.
PRINTSiPR00881. L7ARS6FAMILY.
PR00884. RIBOSOMALHS6.
SUPFAMiSSF55315. SSF55315. 1 hit.
TIGRFAMsiTIGR03677. eL8_ribo. 1 hit.
PROSITEiView protein in PROSITE
PS01082. RIBOSOMAL_L7AE. 1 hit.

Sequencei

Sequence statusi: Complete.

P62008-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKPSYVKFE VPKELAEKAL QAVEIARDTG KIRKGTNETT KAVERGQAKL
60 70 80 90 100
VIIAEDVDPE EIVAHLPPLC EEKEIPYIYV PSKKELGAAA GIEVAAASVA
110 120
IIEPGKARDL VEEIAMKVRE LMK
Length:123
Mass (Da):13,423
Last modified:June 7, 2004 - v1
Checksum:i934817F40CD2D4C5
GO

Sequence cautioni

The sequence CAB49588 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence CCE70060 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ248285 Genomic DNA. Translation: CAB49588.1. Different initiation.
HE613800 Genomic DNA. Translation: CCE70060.1. Different initiation.
PIRiC75109.
RefSeqiWP_048053601.1. NC_000868.1.

Genome annotation databases

EnsemblBacteriaiCAB49588; CAB49588; PAB0460.
GeneIDi1495573.
KEGGipab:PAB0460.
PATRICifig|272844.11.peg.705.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiRL7A_PYRAB
AccessioniPrimary (citable) accession number: P62008
Secondary accession number(s): G8ZJD3, O59165, Q9V0W4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: June 7, 2004
Last modified: June 7, 2017
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families