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Protein

30S ribosomal protein S12

Gene

rps12

Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
30S ribosomal protein S12UniRule annotation
Gene namesi
Name:rps12UniRule annotation
Ordered Locus Names:PF1559
OrganismiPyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Taxonomic identifieri186497 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000001013 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 14714730S ribosomal protein S12PRO_0000146378Add
BLAST

Proteomic databases

PRIDEiP61995.

Interactioni

Subunit structurei

Part of the 30S ribosomal subunit.UniRule annotation

Protein-protein interaction databases

STRINGi186497.PF1559.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4V6Uelectron microscopy6.60AN1-147[»]
ProteinModelPortaliP61995.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S12P family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04255. Archaea.
COG0048. LUCA.
HOGENOMiHOG000040064.
KOiK02950.
OMAiMPGKKSP.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_00403_A. Ribosomal_S12_A.
InterProiIPR012340. NA-bd_OB-fold.
IPR022863. Ribosomal_S12.
IPR006032. Ribosomal_S12/S23.
IPR005680. Ribosomal_S23_euk/arc.
[Graphical view]
PANTHERiPTHR11652. PTHR11652. 1 hit.
PfamiPF00164. Ribosom_S12_S23. 1 hit.
[Graphical view]
PIRSFiPIRSF002133. Ribosomal_S12/S23. 1 hit.
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00982. uS12_E_A. 1 hit.

Sequencei

Sequence statusi: Complete.

P61995-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGKKAPNGE FAGRKLKLKR KKFRWSDIRY KRRVLRLKEK SDPLEGAPQA
60 70 80 90 100
RGIVLEKIAV EAKQPNSGMR KAVRVQLIKN GKVVTAFCPG DGAIKFIDEH
110 120 130 140
DEVIIEGIGG PKGGSMGDIP GIRYKVVKVN RVSLKELVKG RKEKPRR
Length:147
Mass (Da):16,439
Last modified:June 7, 2004 - v1
Checksum:iB8E77B974B2CF5CB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009950 Genomic DNA. Translation: AAL81683.1.
RefSeqiWP_010867743.1. NC_003413.1.

Genome annotation databases

EnsemblBacteriaiAAL81683; AAL81683; PF1559.
GeneIDi1495524.
KEGGipfu:PF1559.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009950 Genomic DNA. Translation: AAL81683.1.
RefSeqiWP_010867743.1. NC_003413.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4V6Uelectron microscopy6.60AN1-147[»]
ProteinModelPortaliP61995.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi186497.PF1559.

Proteomic databases

PRIDEiP61995.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL81683; AAL81683; PF1559.
GeneIDi1495524.
KEGGipfu:PF1559.

Phylogenomic databases

eggNOGiarCOG04255. Archaea.
COG0048. LUCA.
HOGENOMiHOG000040064.
KOiK02950.
OMAiMPGKKSP.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_00403_A. Ribosomal_S12_A.
InterProiIPR012340. NA-bd_OB-fold.
IPR022863. Ribosomal_S12.
IPR006032. Ribosomal_S12/S23.
IPR005680. Ribosomal_S23_euk/arc.
[Graphical view]
PANTHERiPTHR11652. PTHR11652. 1 hit.
PfamiPF00164. Ribosom_S12_S23. 1 hit.
[Graphical view]
PIRSFiPIRSF002133. Ribosomal_S12/S23. 1 hit.
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00982. uS12_E_A. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P. horikoshii inferred from complete genomic sequences."
    Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M., DiRuggiero J., Robb F.T.
    Genetics 152:1299-1305(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43587 / DSM 3638 / JCM 8422 / Vc1.

Entry informationi

Entry nameiRS12_PYRFU
AccessioniPrimary (citable) accession number: P61995
Secondary accession number(s): Q9V110
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: June 7, 2004
Last modified: November 11, 2015
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.