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Protein

30S ribosomal protein S4

Gene

rps4

Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.UniRule annotation
With S5 and S12 plays an important role in translational accuracy.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
30S ribosomal protein S4UniRule annotation
Gene namesi
Name:rps4UniRule annotation
Ordered Locus Names:PF1649
OrganismiPyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Taxonomic identifieri186497 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000001013 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001325171 – 18030S ribosomal protein S4Add BLAST180

Proteomic databases

PRIDEiP61993.

Interactioni

Subunit structurei

Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.UniRule annotation

Protein-protein interaction databases

STRINGi186497.PF1649.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4V6Uelectron microscopy6.60AD1-180[»]
ProteinModelPortaliP61993.
SMRiP61993.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini103 – 174S4 RNA-bindingUniRule annotationAdd BLAST72

Sequence similaritiesi

Belongs to the ribosomal protein S4P family.UniRule annotation
Contains 1 S4 RNA-binding domain.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04239. Archaea.
COG0522. LUCA.
HOGENOMiHOG000194524.
KOiK02986.
OMAiTIVYRKG.

Family and domain databases

Gene3Di3.10.290.10. 1 hit.
HAMAPiMF_01306_A. Ribosomal_S4_A. 1 hit.
InterProiIPR022801. Ribosomal_S4/S9.
IPR005710. Ribosomal_S4/S9_euk/arc.
IPR001912. Ribosomal_S4/S9_N.
IPR022802. Ribosomal_S4_arc.
IPR018079. Ribosomal_S4_CS.
IPR002942. S4_RNA-bd.
[Graphical view]
PANTHERiPTHR11831. PTHR11831. 1 hit.
PfamiPF01479. S4. 1 hit.
[Graphical view]
SMARTiSM01390. Ribosomal_S4. 1 hit.
SM00363. S4. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01018. uS4_arch. 1 hit.
PROSITEiPS00632. RIBOSOMAL_S4. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P61993-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGDPKRQRKK YETPPHPWIK ERLDRERVLM DKYELKNKKE LWKHETQLKN
60 70 80 90 100
FRRRARRLLA ARGKQAEIER EQLLARLKRL GLLPEDAVLD DVLSLTIEDI
110 120 130 140 150
LERRLQTIVY KKGLARTMRQ ARQLIVHGHI EVNGQIIRSP SYLVLKEEED
160 170 180
TITYARTSPF ANPQHPERMM IEKAKQGGEA
Length:180
Mass (Da):21,338
Last modified:June 7, 2004 - v1
Checksum:iD59E61EF49F6CE57
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009950 Genomic DNA. Translation: AAL81773.1.
RefSeqiWP_010867652.1. NC_003413.1.

Genome annotation databases

EnsemblBacteriaiAAL81773; AAL81773; PF1649.
GeneIDi1495430.
KEGGipfu:PF1649.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009950 Genomic DNA. Translation: AAL81773.1.
RefSeqiWP_010867652.1. NC_003413.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4V6Uelectron microscopy6.60AD1-180[»]
ProteinModelPortaliP61993.
SMRiP61993.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi186497.PF1649.

Proteomic databases

PRIDEiP61993.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL81773; AAL81773; PF1649.
GeneIDi1495430.
KEGGipfu:PF1649.

Phylogenomic databases

eggNOGiarCOG04239. Archaea.
COG0522. LUCA.
HOGENOMiHOG000194524.
KOiK02986.
OMAiTIVYRKG.

Family and domain databases

Gene3Di3.10.290.10. 1 hit.
HAMAPiMF_01306_A. Ribosomal_S4_A. 1 hit.
InterProiIPR022801. Ribosomal_S4/S9.
IPR005710. Ribosomal_S4/S9_euk/arc.
IPR001912. Ribosomal_S4/S9_N.
IPR022802. Ribosomal_S4_arc.
IPR018079. Ribosomal_S4_CS.
IPR002942. S4_RNA-bd.
[Graphical view]
PANTHERiPTHR11831. PTHR11831. 1 hit.
PfamiPF01479. S4. 1 hit.
[Graphical view]
SMARTiSM01390. Ribosomal_S4. 1 hit.
SM00363. S4. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01018. uS4_arch. 1 hit.
PROSITEiPS00632. RIBOSOMAL_S4. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRS4_PYRFU
AccessioniPrimary (citable) accession number: P61993
Secondary accession number(s): Q9V199
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: June 7, 2004
Last modified: November 2, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.