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Protein

DNA-binding protein 7a

Gene

sso7a1

more
Organism
Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Constrain negative DNA supercoils; may be involved in maintaining the integrity of their genome at high temperature. Has RNase activity. Has a narrow substrate specificity; the cleavage products are 3'-phosphooligonucleotides.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BRENDAi3.1.27.5. 6163.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-binding protein 7a
Alternative name(s):
7 kDa DNA-binding protein a
Endoribonuclease P2 (EC:3.1.27.-)
p7ss
Gene namesi
Name:sso7a1
Synonyms:sso7d-2
Ordered Locus Names:SSO9180
AND
Name:sso7a2
Synonyms:sso7d-3
Ordered Locus Names:SSO9535
OrganismiSulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Taxonomic identifieri273057 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
Proteomesi
  • UP000001974 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved2 Publications
ChainiPRO_00002130772 – 64DNA-binding protein 7aAdd BLAST63

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei5N6-methyllysine; partial1 Publication1
Modified residuei7N6-methyllysine; partial1 Publication1

Post-translational modificationi

Lys-5 and Lys-7 were found to be 60% monomethylated.

Keywords - PTMi

Methylation

Interactioni

Subunit structurei

Homodimer.Curated

Protein-protein interaction databases

STRINGi273057.SSO9535.

Structurei

Secondary structure

164
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi3 – 10Combined sources8
Beta strandi14 – 16Combined sources3
Beta strandi17 – 19Combined sources3
Beta strandi20 – 25Combined sources6
Beta strandi26 – 29Combined sources4
Beta strandi37 – 39Combined sources3
Beta strandi41 – 47Combined sources7
Beta strandi48 – 50Combined sources3
Helixi53 – 57Combined sources5
Beta strandi58 – 60Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1B4ONMR-A2-63[»]
1JICNMR-A2-63[»]
1SSONMR-A2-63[»]
2CVRNMR-A2-63[»]
ProteinModelPortaliP61991.
SMRiP61991.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP61991.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiarCOG05888. Archaea.
ENOG410YVM7. LUCA.
HOGENOMiHOG000270553.
KOiK16640.
OMAiMATKIKF.

Family and domain databases

InterProiIPR016197. Chromodomain-like.
IPR003212. DNA-bd_7kDa_arc.
[Graphical view]
PfamiPF02294. 7kD_DNA_binding. 1 hit.
[Graphical view]
PIRSFiPIRSF036912. Sac7. 1 hit.
ProDomiPD010328. 7kDa_DNA_bd_arc. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF54160. SSF54160. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P61991-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATVKFKYKG EEKQVDISKI KKVWRVGKMI SFTYDEGGGK TGRGAVSEKD
60
APKELLQMLE KQKK
Length:64
Mass (Da):7,279
Last modified:January 23, 2007 - v2
Checksum:i0E4BA126FCCF84DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006641 Genomic DNA. Translation: AAK42090.1.
AE006641 Genomic DNA. Translation: AAK42212.1.
PIRiE90369.
RefSeqiWP_009992021.1. NC_002754.1.

Genome annotation databases

EnsemblBacteriaiAAK42090; AAK42090; SSO9180.
AAK42212; AAK42212; SSO9535.
GeneIDi7812726.
KEGGisso:SSO9180.
sso:SSO9535.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006641 Genomic DNA. Translation: AAK42090.1.
AE006641 Genomic DNA. Translation: AAK42212.1.
PIRiE90369.
RefSeqiWP_009992021.1. NC_002754.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1B4ONMR-A2-63[»]
1JICNMR-A2-63[»]
1SSONMR-A2-63[»]
2CVRNMR-A2-63[»]
ProteinModelPortaliP61991.
SMRiP61991.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi273057.SSO9535.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK42090; AAK42090; SSO9180.
AAK42212; AAK42212; SSO9535.
GeneIDi7812726.
KEGGisso:SSO9180.
sso:SSO9535.

Phylogenomic databases

eggNOGiarCOG05888. Archaea.
ENOG410YVM7. LUCA.
HOGENOMiHOG000270553.
KOiK16640.
OMAiMATKIKF.

Enzyme and pathway databases

BRENDAi3.1.27.5. 6163.

Miscellaneous databases

EvolutionaryTraceiP61991.

Family and domain databases

InterProiIPR016197. Chromodomain-like.
IPR003212. DNA-bd_7kDa_arc.
[Graphical view]
PfamiPF02294. 7kD_DNA_binding. 1 hit.
[Graphical view]
PIRSFiPIRSF036912. Sac7. 1 hit.
ProDomiPD010328. 7kDa_DNA_bd_arc. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF54160. SSF54160. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiDN71_SULSO
AccessioniPrimary (citable) accession number: P61991
Secondary accession number(s): O59631, P80170, Q9UWI8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: January 23, 2007
Last modified: November 2, 2016
This is version 78 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.