ID   MT1_DROAN               Reviewed;          40 AA.
AC   P61873; P22254;
DT   07-JUN-2004, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2004, sequence version 1.
DT   24-JAN-2024, entry version 48.
DE   RecName: Full=Metallothionein-1;
DE            Short=MT-1;
GN   Name=MtnA;
OS   Drosophila ananassae (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7217;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8001781; DOI=10.1093/genetics/138.1.135;
RA   Stephan W., Rodriguez V.S., Zhou B., Parsch J.;
RT   "Molecular evolution of the metallothionein gene Mtn in the melanogaster
RT   species group: results from Drosophila ananassae.";
RL   Genetics 138:135-143(1994).
CC   -!- FUNCTION: This protein binds cations of several transition elements. It
CC       is thought to be involved in detoxification processes.
CC   -!- DEVELOPMENTAL STAGE: Late embryogenesis, larva and adult.
CC   -!- INDUCTION: Strongly induced by cadmium, copper and mercury.
CC   -!- DOMAIN: All cysteine residues are arranged in C-X-C groups. These are
CC       thought to be the metal-binding sites in other metallothioneins.
CC   -!- SIMILARITY: Belongs to the metallothionein superfamily. Type 5 family.
CC       {ECO:0000305}.
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DR   EMBL; S75822; AAB32801.2; -; Genomic_DNA.
DR   AlphaFoldDB; P61873; -.
DR   eggNOG; KOG4738; Eukaryota.
DR   ChiTaRS; MtnA; fly.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR000966; Metalthion_5.
DR   Pfam; PF02067; Metallothio_5; 1.
DR   PRINTS; PR00872; MTDIPTERA.
PE   2: Evidence at transcript level;
KW   Cadmium; Copper; Metal-binding; Zinc.
FT   CHAIN           1..40
FT                   /note="Metallothionein-1"
FT                   /id="PRO_0000197352"
SQ   SEQUENCE   40 AA;  3852 MW;  9182A53CCCAE634A CRC64;
     MPCPCGSGCK CASQATKGSC NCGSDCKCGG DKKSACGCSK
//