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P61873

- MT1_DROAN

UniProt

P61873 - MT1_DROAN

Protein

Metallothionein-1

Gene

MtnA

Organism
Drosophila ananassae (Fruit fly)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    This protein binds cations of several transition elements. It is thought to be involved in detoxification processes.

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW

    Keywords - Ligandi

    Cadmium, Copper, Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Metallothionein-1
    Short name:
    MT-1
    Gene namesi
    Name:MtnA
    OrganismiDrosophila ananassae (Fruit fly)
    Taxonomic identifieri7217 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

    Organism-specific databases

    FlyBaseiFBgn0013782. Dana\MtnA.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 4040Metallothionein-1PRO_0000197352Add
    BLAST

    Expressioni

    Developmental stagei

    Late embryogenesis, larva and adult.

    Inductioni

    Strongly induced by cadmium, copper and mercury.

    Family & Domainsi

    Domaini

    All cysteine residues are arranged in C-X-C groups. These are thought to be the metal-binding sites in other metallothioneins.

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiNOG262036.
    InParanoidiP61873.
    OrthoDBiEOG789CFK.

    Family and domain databases

    InterProiIPR000966. Metalthion_5.
    [Graphical view]
    PfamiPF02067. Metallothio_5. 1 hit.
    [Graphical view]
    PRINTSiPR00872. MTDIPTERA.

    Sequencei

    Sequence statusi: Complete.

    P61873-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPCPCGSGCK CASQATKGSC NCGSDCKCGG DKKSACGCSK              40
    Length:40
    Mass (Da):3,852
    Last modified:June 7, 2004 - v1
    Checksum:i9182A53CCCAE634A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    S75822 Genomic DNA. Translation: AAB32801.2.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    S75822 Genomic DNA. Translation: AAB32801.2 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    FlyBasei FBgn0013782. Dana\MtnA.

    Phylogenomic databases

    eggNOGi NOG262036.
    InParanoidi P61873.
    OrthoDBi EOG789CFK.

    Family and domain databases

    InterProi IPR000966. Metalthion_5.
    [Graphical view ]
    Pfami PF02067. Metallothio_5. 1 hit.
    [Graphical view ]
    PRINTSi PR00872. MTDIPTERA.
    ProtoNeti Search...

    Publicationsi

    1. "Molecular evolution of the metallothionein gene Mtn in the melanogaster species group: results from Drosophila ananassae."
      Stephan W., Rodriguez V.S., Zhou B., Parsch J.
      Genetics 138:135-143(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

    Entry informationi

    Entry nameiMT1_DROAN
    AccessioniPrimary (citable) accession number: P61873
    Secondary accession number(s): P22254
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 7, 2004
    Last sequence update: June 7, 2004
    Last modified: October 1, 2014
    This is version 27 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programDrosophila annotation project

    Miscellaneousi

    Documents

    1. Drosophila
      Drosophila: entries, gene names and cross-references to FlyBase
    2. Metallothioneins
      Classification of metallothioneins and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3