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P61807

- SNN_MOUSE

UniProt

P61807 - SNN_MOUSE

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Protein

Stannin

Gene

Snn

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Plays a role in the toxic effects of organotins.

Names & Taxonomyi

Protein namesi
Recommended name:
Stannin
Gene namesi
Name:Snn
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 16

Organism-specific databases

MGIiMGI:1276549. Snn.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 1010Mitochondrial intermembraneBy similarity
Transmembranei11 – 3121HelicalSequence AnalysisAdd
BLAST
Topological domaini32 – 8857CytoplasmicBy similarityAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial outer membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion outer membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 8888StanninPRO_0000072015Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei49 – 491Phosphoserine1 Publication
Modified residuei83 – 831Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP61807.
PRIDEiP61807.

PTM databases

PhosphoSiteiP61807.

Expressioni

Gene expression databases

BgeeiP61807.
CleanExiMM_SNN.
ExpressionAtlasiP61807. baseline and differential.
GenevestigatoriP61807.

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

IntActiP61807. 1 interaction.
MINTiMINT-7997209.

Structurei

3D structure databases

ProteinModelPortaliP61807.
SMRiP61807. Positions 1-88.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the stannin family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG47301.
HOGENOMiHOG000261688.
HOVERGENiHBG017824.
InParanoidiP61807.
OMAiYSARGPC.
OrthoDBiEOG7N8ZZJ.
PhylomeDBiP61807.
TreeFamiTF336244.

Family and domain databases

Gene3Di4.10.280.20. 1 hit.
InterProiIPR015137. SNN_cytoplasm.
IPR015136. SNN_linker.
IPR015135. SNN_transmemb.
IPR027435. Stannin.
[Graphical view]
PfamiPF09051. SNN_cytoplasm. 1 hit.
PF09050. SNN_linker. 1 hit.
PF09049. SNN_transmemb. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P61807-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSIMDHSPTT GVVTVIVILI AIAALGALIL GCWCYLRLQR ISQSEDEESI
60 70 80
VGDGETKEPF LLVQYSAKGP CVERKAKLMT ANSPEVHG
Length:88
Mass (Da):9,501
Last modified:June 7, 2004 - v1
Checksum:iEB8DA73323D816C5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF030522 Genomic DNA. Translation: AAC28428.1.
BC017685 mRNA. Translation: AAH17685.1.
BC063027 mRNA. Translation: AAH63027.1.
CCDSiCCDS37255.1.
RefSeqiNP_033249.1. NM_009223.3.
XP_006521943.1. XM_006521880.1.
UniGeneiMm.325800.

Genome annotation databases

EnsembliENSMUST00000089011; ENSMUSP00000086405; ENSMUSG00000037972.
GeneIDi20621.
KEGGimmu:20621.
UCSCiuc007yeq.3. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF030522 Genomic DNA. Translation: AAC28428.1 .
BC017685 mRNA. Translation: AAH17685.1 .
BC063027 mRNA. Translation: AAH63027.1 .
CCDSi CCDS37255.1.
RefSeqi NP_033249.1. NM_009223.3.
XP_006521943.1. XM_006521880.1.
UniGenei Mm.325800.

3D structure databases

ProteinModelPortali P61807.
SMRi P61807. Positions 1-88.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P61807. 1 interaction.
MINTi MINT-7997209.

PTM databases

PhosphoSitei P61807.

Proteomic databases

MaxQBi P61807.
PRIDEi P61807.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000089011 ; ENSMUSP00000086405 ; ENSMUSG00000037972 .
GeneIDi 20621.
KEGGi mmu:20621.
UCSCi uc007yeq.3. mouse.

Organism-specific databases

CTDi 8303.
MGIi MGI:1276549. Snn.

Phylogenomic databases

eggNOGi NOG47301.
HOGENOMi HOG000261688.
HOVERGENi HBG017824.
InParanoidi P61807.
OMAi YSARGPC.
OrthoDBi EOG7N8ZZJ.
PhylomeDBi P61807.
TreeFami TF336244.

Miscellaneous databases

ChiTaRSi Snn. mouse.
NextBioi 299013.
PROi P61807.
SOURCEi Search...

Gene expression databases

Bgeei P61807.
CleanExi MM_SNN.
ExpressionAtlasi P61807. baseline and differential.
Genevestigatori P61807.

Family and domain databases

Gene3Di 4.10.280.20. 1 hit.
InterProi IPR015137. SNN_cytoplasm.
IPR015136. SNN_linker.
IPR015135. SNN_transmemb.
IPR027435. Stannin.
[Graphical view ]
Pfami PF09051. SNN_cytoplasm. 1 hit.
PF09050. SNN_linker. 1 hit.
PF09049. SNN_transmemb. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Chromosomal localization and characterization of the stannin (Snn) gene."
    Dejneka N.S., Polavarapu R., Deng X., Martin-Deleon P.A., Billingsley M.L.
    Mamm. Genome 9:556-564(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/N.
    Tissue: Kidney and Mammary tumor.
  3. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-49 AND SER-83, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Embryonic brain.

Entry informationi

Entry nameiSNN_MOUSE
AccessioniPrimary (citable) accession number: P61807
Secondary accession number(s): O88369
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: June 7, 2004
Last modified: November 26, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3