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Protein

60S ribosomal protein L37a

Gene

Rpl37a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri39 – 6022C4-typeAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-MMU-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-MMU-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-MMU-6791226. Major pathway of rRNA processing in the nucleolus.
R-MMU-72689. Formation of a pool of free 40S subunits.
R-MMU-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-MMU-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-MMU-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L37a
Gene namesi
Name:Rpl37a
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:98068. Rpl37a.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 929160S ribosomal protein L37aPRO_0000139818Add
BLAST

Proteomic databases

EPDiP61514.
PaxDbiP61514.
PeptideAtlasiP61514.
PRIDEiP61514.
TopDownProteomicsiP61514.

PTM databases

iPTMnetiP61514.
PhosphoSiteiP61514.

Expressioni

Gene expression databases

BgeeiENSMUSG00000046330.
CleanExiMM_RPL37A.
ExpressionAtlasiP61514. baseline and differential.
GenevisibleiP61514. MM.

Interactioni

Protein-protein interaction databases

BioGridi202984. 3 interactions.
IntActiP61514. 3 interactions.
MINTiMINT-1843413.
STRINGi10090.ENSMUSP00000058919.

Structurei

3D structure databases

ProteinModelPortaliP61514.
SMRiP61514. Positions 10-81.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L37Ae family.Curated

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri39 – 6022C4-typeAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiKOG0402. Eukaryota.
COG1997. LUCA.
HOVERGENiHBG056620.
InParanoidiP61514.
KOiK02921.
OMAiCKSCKRT.
OrthoDBiEOG091G107U.
PhylomeDBiP61514.
TreeFamiTF313068.

Family and domain databases

Gene3Di2.20.25.30. 1 hit.
HAMAPiMF_00327. Ribosomal_L37Ae. 1 hit.
InterProiIPR002674. Ribosomal_L37ae.
IPR011331. Ribosomal_L37ae/L37e.
IPR011332. Ribosomal_zn-bd.
[Graphical view]
PfamiPF01780. Ribosomal_L37ae. 1 hit.
[Graphical view]
SUPFAMiSSF57829. SSF57829. 1 hit.
TIGRFAMsiTIGR00280. eL43_euk_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P61514-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKRTKKVGI VGKYGTRYGA SLRKMVKKIE ISQHAKYTCS FCGKTKMKRR
60 70 80 90
AVGIWHCGSC MKTVAGGAWT YNTTSAVTVK SAIRRLKELK DQ
Length:92
Mass (Da):10,275
Last modified:January 23, 2007 - v2
Checksum:i7122AF87B0E24CF6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X73331 mRNA. Translation: CAA51758.1.
AK003501 mRNA. Translation: BAB22825.1.
AK011634 mRNA. Translation: BAB27748.1.
AK012396 mRNA. Translation: BAB28213.1.
AK012439 mRNA. Translation: BAB28239.1.
AK012655 mRNA. Translation: BAB28386.1.
AK014283 mRNA. Translation: BAB29243.1.
CCDSiCCDS35610.1.
PIRiS42109.
RefSeqiNP_033110.1. NM_009084.4.
UniGeneiMm.21529.
Mm.491227.

Genome annotation databases

EnsembliENSMUST00000059980; ENSMUSP00000058919; ENSMUSG00000046330.
GeneIDi19981.
KEGGimmu:19981.
UCSCiuc007bkv.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X73331 mRNA. Translation: CAA51758.1.
AK003501 mRNA. Translation: BAB22825.1.
AK011634 mRNA. Translation: BAB27748.1.
AK012396 mRNA. Translation: BAB28213.1.
AK012439 mRNA. Translation: BAB28239.1.
AK012655 mRNA. Translation: BAB28386.1.
AK014283 mRNA. Translation: BAB29243.1.
CCDSiCCDS35610.1.
PIRiS42109.
RefSeqiNP_033110.1. NM_009084.4.
UniGeneiMm.21529.
Mm.491227.

3D structure databases

ProteinModelPortaliP61514.
SMRiP61514. Positions 10-81.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi202984. 3 interactions.
IntActiP61514. 3 interactions.
MINTiMINT-1843413.
STRINGi10090.ENSMUSP00000058919.

PTM databases

iPTMnetiP61514.
PhosphoSiteiP61514.

Proteomic databases

EPDiP61514.
PaxDbiP61514.
PeptideAtlasiP61514.
PRIDEiP61514.
TopDownProteomicsiP61514.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000059980; ENSMUSP00000058919; ENSMUSG00000046330.
GeneIDi19981.
KEGGimmu:19981.
UCSCiuc007bkv.2. mouse.

Organism-specific databases

CTDi6168.
MGIiMGI:98068. Rpl37a.

Phylogenomic databases

eggNOGiKOG0402. Eukaryota.
COG1997. LUCA.
HOVERGENiHBG056620.
InParanoidiP61514.
KOiK02921.
OMAiCKSCKRT.
OrthoDBiEOG091G107U.
PhylomeDBiP61514.
TreeFamiTF313068.

Enzyme and pathway databases

ReactomeiR-MMU-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-MMU-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-MMU-6791226. Major pathway of rRNA processing in the nucleolus.
R-MMU-72689. Formation of a pool of free 40S subunits.
R-MMU-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-MMU-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-MMU-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

ChiTaRSiRpl37a. mouse.
PROiP61514.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000046330.
CleanExiMM_RPL37A.
ExpressionAtlasiP61514. baseline and differential.
GenevisibleiP61514. MM.

Family and domain databases

Gene3Di2.20.25.30. 1 hit.
HAMAPiMF_00327. Ribosomal_L37Ae. 1 hit.
InterProiIPR002674. Ribosomal_L37ae.
IPR011331. Ribosomal_L37ae/L37e.
IPR011332. Ribosomal_zn-bd.
[Graphical view]
PfamiPF01780. Ribosomal_L37ae. 1 hit.
[Graphical view]
SUPFAMiSSF57829. SSF57829. 1 hit.
TIGRFAMsiTIGR00280. eL43_euk_arch. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRL37A_MOUSE
AccessioniPrimary (citable) accession number: P61514
Secondary accession number(s): P12751
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: January 23, 2007
Last modified: September 7, 2016
This is version 116 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.