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Protein

10 kDa chaperonin

Gene

groS

Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Enzyme and pathway databases

BioCyciTTHE262724:GCAT-1746-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
10 kDa chaperonin
Alternative name(s):
GroES protein
Protein Cpn10
Gene namesi
Name:groS
Synonyms:chpS, groES, hsp10
Ordered Locus Names:TT_C1713
OrganismiThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Taxonomic identifieri262724 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000000592 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 10110010 kDa chaperoninPRO_0000174885Add
BLAST

Interactioni

Subunit structurei

Heptamer of 7 subunits arranged in a ring.By similarity

Protein-protein interaction databases

STRINGi262724.TTC1713.

Structurei

Secondary structure

1
101
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi9 – 113Combined sources
Beta strandi16 – 205Combined sources
Turni35 – 373Combined sources
Beta strandi42 – 476Combined sources
Beta strandi70 – 734Combined sources
Beta strandi78 – 825Combined sources
Beta strandi87 – 915Combined sources
Turni93 – 953Combined sources
Beta strandi96 – 1005Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4V4OX-ray2.80O/P/Q/R/S/T/U/o/p/q/r/s/t/u2-101[»]
ProteinModelPortaliP61492.
SMRiP61492. Positions 6-101.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP61492.

Family & Domainsi

Sequence similaritiesi

Belongs to the GroES chaperonin family.Curated

Phylogenomic databases

eggNOGiENOG4105K5Y. Bacteria.
COG0234. LUCA.
KOiK04078.
OMAiDTGKEKP.

Family and domain databases

CDDicd00320. cpn10. 1 hit.
Gene3Di2.30.33.40. 1 hit.
HAMAPiMF_00580. CH10. 1 hit.
InterProiIPR020818. Chaperonin_GroES.
IPR018369. Chaprnonin_Cpn10_CS.
IPR011032. GroES-like.
[Graphical view]
PANTHERiPTHR10772. PTHR10772. 1 hit.
PfamiPF00166. Cpn10. 1 hit.
[Graphical view]
PRINTSiPR00297. CHAPERONIN10.
SMARTiSM00883. Cpn10. 1 hit.
[Graphical view]
SUPFAMiSSF50129. SSF50129. 1 hit.
PROSITEiPS00681. CHAPERONINS_CPN10. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P61492-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAEVKTVIK PLGDRVVVKR IEEEPKTKGG IVLPDTAKEK PQKGKVIAVG
60 70 80 90 100
TGRVLENGQR VPLEVKEGDI VVFAKYGGTE IEIDGEEYVI LSERDLLAVL

Q
Length:101
Mass (Da):10,996
Last modified:January 23, 2007 - v2
Checksum:i49DCA870AC325063
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ250409 Genomic DNA. Translation: CAB65481.1.
AE017221 Genomic DNA. Translation: AAS82055.1.
RefSeqiWP_011174076.1. NC_005835.1.

Genome annotation databases

EnsemblBacteriaiAAS82055; AAS82055; TT_C1713.
KEGGitth:TTC1713.
PATRICi23953883. VBITheThe54392_1712.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ250409 Genomic DNA. Translation: CAB65481.1.
AE017221 Genomic DNA. Translation: AAS82055.1.
RefSeqiWP_011174076.1. NC_005835.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4V4OX-ray2.80O/P/Q/R/S/T/U/o/p/q/r/s/t/u2-101[»]
ProteinModelPortaliP61492.
SMRiP61492. Positions 6-101.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi262724.TTC1713.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAS82055; AAS82055; TT_C1713.
KEGGitth:TTC1713.
PATRICi23953883. VBITheThe54392_1712.

Phylogenomic databases

eggNOGiENOG4105K5Y. Bacteria.
COG0234. LUCA.
KOiK04078.
OMAiDTGKEKP.

Enzyme and pathway databases

BioCyciTTHE262724:GCAT-1746-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP61492.

Family and domain databases

CDDicd00320. cpn10. 1 hit.
Gene3Di2.30.33.40. 1 hit.
HAMAPiMF_00580. CH10. 1 hit.
InterProiIPR020818. Chaperonin_GroES.
IPR018369. Chaprnonin_Cpn10_CS.
IPR011032. GroES-like.
[Graphical view]
PANTHERiPTHR10772. PTHR10772. 1 hit.
PfamiPF00166. Cpn10. 1 hit.
[Graphical view]
PRINTSiPR00297. CHAPERONIN10.
SMARTiSM00883. Cpn10. 1 hit.
[Graphical view]
SUPFAMiSSF50129. SSF50129. 1 hit.
PROSITEiPS00681. CHAPERONINS_CPN10. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCH10_THET2
AccessioniPrimary (citable) accession number: P61492
Secondary accession number(s): P45747, Q60017
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: January 23, 2007
Last modified: September 7, 2016
This is version 83 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.