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Reviewed, UniProtKB/Swiss-Prot P61433 (MURB_BDEBA)

Last modified November 3, 2009. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    UDP-N-acetylenolpyruvoylglucosamine reductase
    EC=1.1.1.158
Alternative name(s):
    UDP-N-acetylmuramate dehydrogenase
Gene names
Name: murB
Ordered Locus Names: Bd3233
OrganismBdellovibrio bacteriovorus [Complete proteome] [HAMAP]
Taxonomic identifier959 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Deltaproteobacteria › Bdellovibrionales › Bdellovibrionaceae › Bdellovibrio

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Protein attributes

Sequence length336 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Cell wall formation By similarity.

Catalytic activity

UDP-N-acetylmuramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine + NADPH. HAMAP MF_00037

Cofactor

FAD By similarity.

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00037

Subcellular location

Cytoplasm Probable.

Sequence similarities

Belongs to the murB family.

Contains 1 FAD-binding PCMH-type domain.

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 336336UDP-N-acetylenolpyruvoylglucosamine reductase HAMAP MF_00037
PRO_0000179179

Regions

Domain17 – 188172FAD-binding PCMH-type

Sites

Active site1641 By similarity
Active site2371Proton donor By similarity
Active site3321 By similarity

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Sequences

Sequence LengthMass (Da)Tools
P61433-1 [UniParc].

Last modified May 24, 2004. Version 1.
Checksum: FA5352363B3F713A

FASTA33638,105
        10         20         30         40         50         60 
MQIQNSHDLS SSNTLQLRSL AERFVELYTP ADLSTLLMNP ELKNLPWKIL GGGSNLVLPS 

        70         80         90        100        110        120 
QIEGLVLKVS NLGRKLIHED PDYWFVKAQA GEVWNDFVQW TLEEGYWGLE NLSLIPGTVG 

       130        140        150        160        170        180 
AAPIQNIGAY GVEVKDTLWE VHALDLQTGE PRVFSNKECQ FSYRDSYFKQ EGAGRYLIWD 

       190        200        210        220        230        240 
VTFRLPKKNV LHLEYGDIRK EVERNNWPQD PRHVAQAVIN IRQSKLPDPK VIGNAGSFFK 

       250        260        270        280        290        300 
NPIVSKELRD GLLSKHNDLV SFPYEDRYKL AAGWLIDRAG WKGKKLGPVG MYEKQALVLV 

       310        320        330 
NHGGATADDV WKLARQVSSD VHTQFGVEIE AEPIRW

« Hide

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References

[1]"A predator unmasked: life cycle of Bdellovibrio bacteriovorus from a genomic perspective."
Rendulic S., Jagtap P., Rosinus A., Eppinger M., Baar C., Lanz C., Keller H., Lambert C., Evans K.J., Goesmann A., Meyer F., Sockett R.E., Schuster S.C.
Science 303:689-692(2004) [PubMed: 14752164] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 15356 / HD100 / DSM 50701 / NCIB 9529.

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Cross-references

Sequence databases

BX842655 Genomic DNA. Translation: CAE78050.1.
RefSeqNP_969991.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID2736854.
GenomeReviewsGene locus Bd3233 in contig BX842601_GR.
KEGGbba:Bd3233.
NMPDRfig|264462.1.peg.2964.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMP61433.
OMAIGNAGSF.

Enzyme and pathway databases

BioCycBBAC264462:BD3233-MON.
BRENDA1.1.1.158. 3459.

Family and domain databases

HAMAPMF_00037.
[Tree]
InterProIPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR016166. FAD-bd_2.
IPR016167. FAD-bd_2_sub1.
IPR003170. MurB.
IPR011601. MurB_C.
IPR006094. Oxid_FAD_bind_N.
[Graphical view]
Gene3DG3DSA:3.30.465.10. CO_DH_flavoprot_FAD-bd_sub2. 1 hit.
G3DSA:3.30.43.10. FAD-binding_2_sub1. 1 hit.
G3DSA:3.90.78.10. MurB_C. 1 hit.
PANTHERPTHR21071. MurB. 1 hit.
PfamPF01565. FAD_binding_4. 1 hit.
PF02873. MurB_C. 1 hit.
[Graphical view]
TIGRFAMsTIGR00179. murB. 1 hit.
PROSITEPS51387. FAD_PCMH. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameMURB_BDEBA
AccessionPrimary (citable) accession number: P61433
Entry history
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: May 24, 2004
Last modified: November 3, 2009
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents