Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

60S ribosomal protein L27

Gene

Rpl27

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of the large ribosomal subunit (By similarity). Required for proper rRNA processing and maturation of 28S and 5.8S rRNAs (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L27
Gene namesi
Name:Rpl27
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi

Organism-specific databases

MGIiMGI:98036 Rpl27

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001260781 – 13660S ribosomal protein L27Add BLAST136

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei27N6-acetyllysineCombined sources1
Modified residuei93N6-acetyllysineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

EPDiP61358
PaxDbiP61358
PeptideAtlasiP61358
PRIDEiP61358
TopDownProteomicsiP61358

PTM databases

iPTMnetiP61358
PhosphoSitePlusiP61358
SwissPalmiP61358

Expressioni

Gene expression databases

BgeeiENSMUSG00000063316
CleanExiMM_RPL27
ExpressionAtlasiP61358 baseline and differential
GenevisibleiP61358 MM

Interactioni

Subunit structurei

Component of the large ribosomal subunit (By similarity). Interacts with RRP1B (By similarity). Interacts with DHX33 (PubMed:26100019).By similarity1 Publication

Protein-protein interaction databases

BioGridi202974, 7 interactors
IntActiP61358, 2 interactors
MINTiP61358
STRINGi10090.ENSMUSP00000095287

Structurei

3D structure databases

ProteinModelPortaliP61358
SMRiP61358
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 40KOWAdd BLAST36

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3418 Eukaryota
COG2163 LUCA
GeneTreeiENSGT00390000010721
HOGENOMiHOG000210138
HOVERGENiHBG050005
InParanoidiP61358
KOiK02901
OMAiRYPRKVH
OrthoDBiEOG091G0YBM
PhylomeDBiP61358
TreeFamiTF314648

Family and domain databases

Gene3Di2.30.30.770, 1 hit
InterProiView protein in InterPro
IPR005824 KOW
IPR038655 L27e_sf
IPR001141 Ribosomal_L27e
IPR018262 Ribosomal_L27e_CS
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR10497 PTHR10497, 1 hit
PfamiView protein in Pfam
PF00467 KOW, 1 hit
PF01777 Ribosomal_L27e, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD009396 Ribosomal_L27e, 1 hit
SMARTiView protein in SMART
SM00739 KOW, 1 hit
SUPFAMiSSF50104 SSF50104, 1 hit
PROSITEiView protein in PROSITE
PS01107 RIBOSOMAL_L27E, 1 hit

Sequencei

Sequence statusi: Complete.

P61358-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKFMKPGKV VLVLAGRYSG RKAVIVKNID DGTSDRPYSH ALVAGIDRYP
60 70 80 90 100
RKVTAAMGKK KIAKRSKIKS FVKVYNYNHL MPTRYSVDIP LDKTVVNKDV
110 120 130
FRDPALKRKA RREAKVKFEE RYKTGKNKWF FQKLRF
Length:136
Mass (Da):15,798
Last modified:January 23, 2007 - v2
Checksum:i73F4151495029A32
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF214527 mRNA Translation: AAF25951.1
AK002945 mRNA Translation: BAB22471.1
AK008120 mRNA Translation: BAB25475.1
AK088211 mRNA Translation: BAC40213.1
AK010627 mRNA Translation: BAB27073.1
AK012566 mRNA Translation: BAB28321.1
BC024366 mRNA Translation: AAH24366.1
BC082284 mRNA Translation: AAH82284.1
CCDSiCCDS25470.1
RefSeqiNP_035419.1, NM_011289.3
XP_017170385.1, XM_017314896.1
UniGeneiMm.340658
Mm.439813

Genome annotation databases

EnsembliENSMUST00000077856; ENSMUSP00000090305; ENSMUSG00000063316
ENSMUST00000097682; ENSMUSP00000095287; ENSMUSG00000073640
ENSMUST00000107249; ENSMUSP00000102870; ENSMUSG00000063316
GeneIDi108167922
19942
KEGGimmu:108167922
mmu:19942
UCSCiuc007low.2 mouse

Entry informationi

Entry nameiRL27_MOUSE
AccessioniPrimary (citable) accession number: P61358
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 139 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health