Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

60S ribosomal protein L27

Gene

Rpl27

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • response to aldosterone Source: RGD
  • translation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-RNO-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-RNO-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-RNO-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.
R-RNO-72689. Formation of a pool of free 40S subunits.
R-RNO-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-RNO-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-RNO-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L27
Gene namesi
Name:Rpl27
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi621192. Rpl27.

Subcellular locationi

GO - Cellular componenti

  • cytosolic large ribosomal subunit Source: RGD
  • ribosome Source: RGD
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001260791 – 13660S ribosomal protein L27Add BLAST136

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei27N6-acetyllysineBy similarity1
Modified residuei93N6-acetyllysineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiP61354.
PRIDEiP61354.

PTM databases

iPTMnetiP61354.
PhosphoSitePlusiP61354.
SwissPalmiP61354.

Expressioni

Gene expression databases

BgeeiENSRNOG00000020674.
GenevisibleiP61354. RN.

Interactioni

Protein-protein interaction databases

BioGridi249021. 3 interactors.
IntActiP61354. 1 interactor.
MINTiMINT-4578026.
STRINGi10116.ENSRNOP00000028060.

Structurei

3D structure databases

ProteinModelPortaliP61354.
SMRiP61354.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 40KOWAdd BLAST36

Sequence similaritiesi

Belongs to the ribosomal protein L27e family.Curated
Contains 1 KOW domain.Curated

Phylogenomic databases

eggNOGiKOG3418. Eukaryota.
COG2163. LUCA.
GeneTreeiENSGT00390000010721.
HOGENOMiHOG000210138.
HOVERGENiHBG050005.
InParanoidiP61354.
KOiK02901.
OMAiFNYNHLM.
OrthoDBiEOG091G0YBM.
PhylomeDBiP61354.
TreeFamiTF314648.

Family and domain databases

Gene3Di2.30.30.30. 1 hit.
InterProiIPR005824. KOW.
IPR014722. Rib_L2_dom2.
IPR001141. Ribosomal_L27e.
IPR018262. Ribosomal_L27e_CS.
IPR008991. Translation_prot_SH3-like.
[Graphical view]
PANTHERiPTHR10497. PTHR10497. 1 hit.
PfamiPF00467. KOW. 1 hit.
PF01777. Ribosomal_L27e. 1 hit.
[Graphical view]
ProDomiPD009396. Ribosomal_L27e. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00739. KOW. 1 hit.
[Graphical view]
SUPFAMiSSF50104. SSF50104. 1 hit.
PROSITEiPS01107. RIBOSOMAL_L27E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P61354-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKFMKPGKV VLVLAGRYSG RKAVIVKNID DGTSDRPYSH ALVAGIDRYP
60 70 80 90 100
RKVTAAMGKK KIAKRSKIKS FVKVYNYNHL MPTRYSVDIP LDKTVVNKDV
110 120 130
FRDPALKRKA RREAKVKFEE RYKTGKNKWF FQKLRF
Length:136
Mass (Da):15,798
Last modified:January 23, 2007 - v2
Checksum:i73F4151495029A32
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X07424 mRNA. Translation: CAA30313.1.
BC058474 mRNA. Translation: AAH58474.1.
BC091566 mRNA. Translation: AAH91566.1.
PIRiS00401. R5RT27.
RefSeqiNP_071959.1. NM_022514.1.
UniGeneiRn.1254.

Genome annotation databases

EnsembliENSRNOT00000028060; ENSRNOP00000028060; ENSRNOG00000020674.
GeneIDi64306.
KEGGirno:64306.
UCSCiRGD:621192. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X07424 mRNA. Translation: CAA30313.1.
BC058474 mRNA. Translation: AAH58474.1.
BC091566 mRNA. Translation: AAH91566.1.
PIRiS00401. R5RT27.
RefSeqiNP_071959.1. NM_022514.1.
UniGeneiRn.1254.

3D structure databases

ProteinModelPortaliP61354.
SMRiP61354.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi249021. 3 interactors.
IntActiP61354. 1 interactor.
MINTiMINT-4578026.
STRINGi10116.ENSRNOP00000028060.

PTM databases

iPTMnetiP61354.
PhosphoSitePlusiP61354.
SwissPalmiP61354.

Proteomic databases

PaxDbiP61354.
PRIDEiP61354.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000028060; ENSRNOP00000028060; ENSRNOG00000020674.
GeneIDi64306.
KEGGirno:64306.
UCSCiRGD:621192. rat.

Organism-specific databases

CTDi6155.
RGDi621192. Rpl27.

Phylogenomic databases

eggNOGiKOG3418. Eukaryota.
COG2163. LUCA.
GeneTreeiENSGT00390000010721.
HOGENOMiHOG000210138.
HOVERGENiHBG050005.
InParanoidiP61354.
KOiK02901.
OMAiFNYNHLM.
OrthoDBiEOG091G0YBM.
PhylomeDBiP61354.
TreeFamiTF314648.

Enzyme and pathway databases

ReactomeiR-RNO-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-RNO-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-RNO-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.
R-RNO-72689. Formation of a pool of free 40S subunits.
R-RNO-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-RNO-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-RNO-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

PROiP61354.

Gene expression databases

BgeeiENSRNOG00000020674.
GenevisibleiP61354. RN.

Family and domain databases

Gene3Di2.30.30.30. 1 hit.
InterProiIPR005824. KOW.
IPR014722. Rib_L2_dom2.
IPR001141. Ribosomal_L27e.
IPR018262. Ribosomal_L27e_CS.
IPR008991. Translation_prot_SH3-like.
[Graphical view]
PANTHERiPTHR10497. PTHR10497. 1 hit.
PfamiPF00467. KOW. 1 hit.
PF01777. Ribosomal_L27e. 1 hit.
[Graphical view]
ProDomiPD009396. Ribosomal_L27e. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00739. KOW. 1 hit.
[Graphical view]
SUPFAMiSSF50104. SSF50104. 1 hit.
PROSITEiPS01107. RIBOSOMAL_L27E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRL27_RAT
AccessioniPrimary (citable) accession number: P61354
Secondary accession number(s): P08526, Q5BJ97
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: January 23, 2007
Last modified: November 30, 2016
This is version 93 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.