P61336 (EFTS_MYCPA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Elongation factor Ts
Short name=EF-Ts

Gene names

Name:	tsf
Ordered Locus Names:	MAP_2955c

Organism

Mycobacterium paratuberculosis [Complete proteome] [HAMAP]

Taxonomic identifier

1770 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium avium complex (MAC)

Protein attributes

Sequence length	275 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. HAMAP MF_00050
Subcellular location	Cytoplasm HAMAP MF_00050.
Sequence similarities	Belongs to the EF-Ts family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Molecular function	Elongation factor
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	translation elongation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 275	275	Elongation factor Ts HAMAP MF_00050		PRO_0000161156
Regions
	Region	76 – 79	4	Involved in Mg(2+) ion dislocation from EF-Tu By similarity

Sequences

	Sequence		Length	Mass (Da)
	P61336 [UniParc]. Last modified May 10, 2004. Version 1. Checksum: 67399F0466836CEA	FASTA	275	29,084
	10 20 30 40 50 60 MANFTAADVK RLRELTGAGM LDCKNALAES DGDFDKAVEA LRIKGAKDVG KRAERATAEG 70 80 90 100 110 120 LVAAQGGALI ELNSETDFVA KNAEFQALAD QIVAAAASSK AADVDALKAA KIGDTTVEQA 130 140 150 160 170 180 IAELSAKIGE KLELRRVAHF DGTVEAYLHR RAADLPPAVG VLVEYQGSGK DSDKEAAHAV 190 200 210 220 230 240 ALQIAALKAR YLSRGDVPED VVASERRIAE ETAKAEGKPE QALPKIVEGR LNGFFKDAVL 250 260 270 LEQPSVSDSK KTVKALLDEA GVTVTRFVRF EVGQA

References

[1]

"The complete genome sequence of Mycobacterium avium subspecies paratuberculosis." Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N., Kanjilal S., Kapur V. Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005) [PubMed: 16116077] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-968 / K-10.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016958 Genomic DNA. Translation: AAS05272.1.
RefSeq	NP_961889.1. NC_002944.2.
3D structure databases
ProteinModelPortal	P61336.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000036379; EBMYCP00000034768; EBMYCG00000036374.
GeneID	2719457.
GenomeReviews	Gene locus MAP_2955c in contig AE016958_GR.
KEGG	mpa:MAP2955c.
NMPDR	fig|262316.1.peg.2955.
PATRIC	17998642. VBIMycAvi108102_3131.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000016347.
HOGENOM	HBG713289.
OMA	YLHGTRI.
ProtClustDB	PRK09377.
Family and domain databases
HAMAP	MF_00050. EF_Ts. [Tree]
InterPro	IPR001816. Transl_elong_EFTs/EF1B. IPR014039. Transl_elong_EFTs/EF1B_dimer. IPR018101. Transl_elong_Ts_CS. IPR009060. UBA-like. IPR000449. UBA/transl_elong_EF1B_N. [Graphical view]
Gene3D	G3DSA:3.30.479.20. Transl_elong_EFTs/EF1B_dimer. 3 hits.
KO	K02357.
PANTHER	PTHR11741. Transl_elong_EFTs/EF1B. 1 hit.
Pfam	PF00889. EF_TS. 1 hit. PF00627. UBA. 1 hit. [Graphical view]
SUPFAM	SSF54713. EF_TS. 1 hit. SSF46934. UBA_like. 1 hit.
TIGRFAMs	TIGR00116. Tsf. 1 hit.
PROSITE	PS01126. EF_TS_1. 1 hit. PS01127. EF_TS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EFTS_MYCPA

Accession

Primary (citable) accession number: P61336

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 10, 2004
Last sequence update:	May 10, 2004
Last modified:	January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program