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Protein

Elongation factor Ts

Gene

tsf

Organism
Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Elongation factor

Keywords - Biological processi

Protein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TsUniRule annotation
Short name:
EF-TsUniRule annotation
Gene namesi
Name:tsfUniRule annotation
Ordered Locus Names:DIP1507
OrganismiCorynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)
Taxonomic identifieri257309 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesCorynebacteriaceaeCorynebacterium
Proteomesi
  • UP000002198 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001611101 – 275Elongation factor TsAdd BLAST275

Structurei

3D structure databases

ProteinModelPortaliP61332.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni76 – 79Involved in Mg(2+) ion dislocation from EF-TuUniRule annotation4

Sequence similaritiesi

Belongs to the EF-Ts family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000220986.
KOiK02357.
OMAiFIMEPKK.

Family and domain databases

Gene3Di3.30.479.20. 3 hits.
HAMAPiMF_00050. EF_Ts. 1 hit.
InterProiIPR001816. Transl_elong_EFTs/EF1B.
IPR014039. Transl_elong_EFTs/EF1B_dimer.
IPR018101. Transl_elong_Ts_CS.
IPR009060. UBA-like.
[Graphical view]
PANTHERiPTHR11741. PTHR11741. 1 hit.
PfamiPF00889. EF_TS. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
SSF54713. SSF54713. 2 hits.
TIGRFAMsiTIGR00116. tsf. 1 hit.
PROSITEiPS01126. EF_TS_1. 1 hit.
PS01127. EF_TS_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P61332-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANYTAADVK KLREITGSGM LDCKKALEET NGDFDKAVEV LRIKGAKDVG
60 70 80 90 100
KRAERNATEG LIAVSGNTMV EINSETDFVA KNAEFKEFAQ KVADAAAAVK
110 120 130 140 150
ANTPEELAAA DLDGKTAADA IQELSAKIGE KLELRRAITL EGEKLSVYLH
160 170 180 190 200
QRSADLPPAV GVLVAYTGEG EAAQAAAHAA AMQVAALKAQ YLTREDVPAE
210 220 230 240 250
VIEKERSIAE QITREEGKPE KAIPKIVEGR LNGFYKDVCL VEQASVADSK
260 270
KTVKQVMDEA GVTLTGFARY EVGQH
Length:275
Mass (Da):29,463
Last modified:May 10, 2004 - v1
Checksum:i851DE2992CF40121
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX248358 Genomic DNA. Translation: CAE50034.1.
RefSeqiWP_010935114.1. NC_002935.2.

Genome annotation databases

EnsemblBacteriaiCAE50034; CAE50034; DIP1507.
GeneIDi2650391.
KEGGicdi:DIP1507.
PATRICi21484224. VBICorDip47633_1488.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX248358 Genomic DNA. Translation: CAE50034.1.
RefSeqiWP_010935114.1. NC_002935.2.

3D structure databases

ProteinModelPortaliP61332.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAE50034; CAE50034; DIP1507.
GeneIDi2650391.
KEGGicdi:DIP1507.
PATRICi21484224. VBICorDip47633_1488.

Phylogenomic databases

HOGENOMiHOG000220986.
KOiK02357.
OMAiFIMEPKK.

Family and domain databases

Gene3Di3.30.479.20. 3 hits.
HAMAPiMF_00050. EF_Ts. 1 hit.
InterProiIPR001816. Transl_elong_EFTs/EF1B.
IPR014039. Transl_elong_EFTs/EF1B_dimer.
IPR018101. Transl_elong_Ts_CS.
IPR009060. UBA-like.
[Graphical view]
PANTHERiPTHR11741. PTHR11741. 1 hit.
PfamiPF00889. EF_TS. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
SSF54713. SSF54713. 2 hits.
TIGRFAMsiTIGR00116. tsf. 1 hit.
PROSITEiPS01126. EF_TS_1. 1 hit.
PS01127. EF_TS_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiEFTS_CORDI
AccessioniPrimary (citable) accession number: P61332
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: May 10, 2004
Last modified: September 7, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.