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Protein

Translationally-controlled tumor protein

Gene

TPT1

Organism
Sus scrofa (Pig)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in calcium binding and microtubule stabilization.By similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Calcium

Names & Taxonomyi

Protein namesi
Recommended name:
Translationally-controlled tumor protein
Short name:
TCTP
Gene namesi
Name:TPT1
OrganismiSus scrofa (Pig)
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 172172Translationally-controlled tumor proteinPRO_0000211270Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei46 – 461Phosphoserine; by PLK1By similarity
Modified residuei53 – 531PhosphoserineBy similarity
Modified residuei64 – 641Phosphoserine; by PLK1By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PeptideAtlasiP61288.
PRIDEiP61288.

Interactioni

Subunit structurei

Interacts with STEAP3.By similarity

Structurei

3D structure databases

ProteinModelPortaliP61288.
SMRiP61288. Positions 1-172.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 172172TCTPPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the TCTP family.PROSITE-ProRule annotation
Contains 1 TCTP domain.PROSITE-ProRule annotation

Phylogenomic databases

HOVERGENiHBG002282.
InParanoidiP61288.

Family and domain databases

Gene3Di2.170.150.10. 1 hit.
InterProiIPR011057. Mss4-like.
IPR011323. Mss4/transl-control_tumor.
IPR018103. Translation_control_tumour_CS.
IPR018105. Translational_control_tumour_p.
[Graphical view]
PANTHERiPTHR11991. PTHR11991. 1 hit.
PfamiPF00838. TCTP. 1 hit.
[Graphical view]
PRINTSiPR01653. TCTPROTEIN.
SUPFAMiSSF51316. SSF51316. 1 hit.
PROSITEiPS01002. TCTP_1. 1 hit.
PS01003. TCTP_2. 1 hit.
PS51797. TCTP_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P61288-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIIYRDLISH DEMFSDIYKI REIADGLCLE VEGKMVSRTE GNIDDSLIGG
60 70 80 90 100
NASAEGPEGE GTESTVITGV DIVMNHHLQE TSFTKEAYKK YIKDYMKSIK
110 120 130 140 150
GKLEEQRPER VKPFMTGAAE QIKHILANFK NYQFFIGENM NPDGMVALLD
160 170
YREDGVTPYM IFFKDGLEME KC
Length:172
Mass (Da):19,595
Last modified:May 10, 2004 - v1
Checksum:iBD31399B71CA62F9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY072784 mRNA. Translation: AAL68965.1.
RefSeqiNP_999538.1. NM_214373.1.
UniGeneiSsc.49584.
Ssc.95493.

Genome annotation databases

GeneIDi397664.
KEGGissc:397664.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY072784 mRNA. Translation: AAL68965.1.
RefSeqiNP_999538.1. NM_214373.1.
UniGeneiSsc.49584.
Ssc.95493.

3D structure databases

ProteinModelPortaliP61288.
SMRiP61288. Positions 1-172.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiP61288.
PRIDEiP61288.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi397664.
KEGGissc:397664.

Organism-specific databases

CTDi7178.

Phylogenomic databases

HOVERGENiHBG002282.
InParanoidiP61288.

Family and domain databases

Gene3Di2.170.150.10. 1 hit.
InterProiIPR011057. Mss4-like.
IPR011323. Mss4/transl-control_tumor.
IPR018103. Translation_control_tumour_CS.
IPR018105. Translational_control_tumour_p.
[Graphical view]
PANTHERiPTHR11991. PTHR11991. 1 hit.
PfamiPF00838. TCTP. 1 hit.
[Graphical view]
PRINTSiPR01653. TCTPROTEIN.
SUPFAMiSSF51316. SSF51316. 1 hit.
PROSITEiPS01002. TCTP_1. 1 hit.
PS01003. TCTP_2. 1 hit.
PS51797. TCTP_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Molecular characterization of the gene coding for the pig translationally controlled tumor protein (TCTP)."
    Yubero N., Barbancho M.J., Llanes D., Garrido J.J.
    Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiTCTP_PIG
AccessioniPrimary (citable) accession number: P61288
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: May 10, 2004
Last modified: July 6, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.