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Protein

60S ribosomal protein L35a

Gene

RPL35A

Organism
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Required for the proliferation and viability of hematopoietic cells. Plays a role in 60S ribosomal subunit formation. The protein was found to bind to both initiator and elongator tRNAs and consequently was assigned to the P site or P and A site.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, tRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L35a
Gene namesi
Name:RPL35A
ORF Names:QnpA-15663
OrganismiMacaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Taxonomic identifieri9541 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001927971 – 11060S ribosomal protein L35aAdd BLAST110

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei8N6-acetyllysineBy similarity1
Modified residuei63N6-acetyllysine; alternateBy similarity1
Modified residuei63N6-succinyllysine; alternateBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

PRIDEiP61272.

Structurei

3D structure databases

ProteinModelPortaliP61272.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOVERGENiHBG054581.
KOiK02917.

Family and domain databases

HAMAPiMF_00573. Ribosomal_L35Ae. 1 hit.
InterProiView protein in InterPro
IPR001780. Ribosomal_L35A.
IPR018266. Ribosomal_L35Ae_CS.
IPR009000. Transl_B-barrel.
PANTHERiPTHR10902. PTHR10902. 1 hit.
PfamiView protein in Pfam
PF01247. Ribosomal_L35Ae. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD012670. Ribosomal_L35Ae. 1 hit.
SUPFAMiSSF50447. SSF50447. 1 hit.
PROSITEiView protein in PROSITE
PS01105. RIBOSOMAL_L35AE. 1 hit.

Sequencei

Sequence statusi: Complete.

P61272-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGRLWSKAI FAGYKRGLRN QREHTALLKI EGVYARDETE FYLGKRCAYV
60 70 80 90 100
YKAKNNTVTP GGKPNKTRVI WGKVTRAHGN SGMVRAKFRS NLPAKAIGHR
110
IRVMLYPSRI
Length:110
Mass (Da):12,538
Last modified:May 10, 2004 - v1
Checksum:iF32E4A26A25E79E8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB093673 mRNA. Translation: BAC21647.1.
RefSeqiNP_001270366.1. NM_001283437.1.
XP_015300053.1. XM_015444567.1.
UniGeneiMfa.8218.

Genome annotation databases

GeneIDi102120755.
KEGGimcf:102120755.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiRL35A_MACFA
AccessioniPrimary (citable) accession number: P61272
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: May 10, 2004
Last modified: May 10, 2017
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families