P61255 (RL26_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
60S ribosomal protein L26

Alternative name(s):
Silica-induced gene 20 protein
Short name=SIG-20

Gene names

Name:

Rpl26

Organism

Mus musculus (Mouse) [Reference proteome]

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	145 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Induction	Up-regulated in silica-treated macrophages. Ref.1
Sequence similarities	Belongs to the ribosomal protein L24P family.

Ontologies

Keywords
Molecular function	Ribonucleoprotein Ribosomal protein
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	rRNA processing Inferred from electronic annotation. Source: Compara ribosomal large subunit biogenesis Inferred from electronic annotation. Source: Compara translation Inferred from electronic annotation. Source: InterPro
Cellular_component	cytosolic large ribosomal subunit Inferred from electronic annotation. Source: Compara
Molecular_function	structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 145	145	60S ribosomal protein L26		PRO_0000130789
Amino acid modifications
	Modified residue	139	1	Phosphothreonine By similarity

Sequences

	Sequence		Length	Mass (Da)
	P61255 [UniParc]. Last modified May 10, 2004. Version 1. Checksum: 049D53AB4E3F46B6	FASTA	145	17,258
	10 20 30 40 50 60 MKFNPFVTSD RSKNRKRHFN APSHIRRKIM SSPLSKELRQ KYNVRSMPIR KDDEVQVVRG 70 80 90 100 110 120 HYKGQQIGKV VQVYRKKYVI YIERVQREKA NGTTVHVGIH PSKVVITRLK LDKDRKKILE 130 140 RKAKSRQVGK EKGKYKEETI EKMQE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Isolation of nine gene sequences induced by silica in murine macrophages." Segade F., Claudio E., Wrobel K., Ramos S., Lazo P.S. J. Immunol. 154:2384-2392(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], INDUCTION. Tissue: Macrophage.
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6. Tissue: Brain.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X80699 mRNA. Translation: CAA56716.1. BC070397 mRNA. Translation: AAH70397.1.
IPI	IPI00132460.
PIR	S48864. I48616.
RefSeq	NP_033106.1. NM_009080.2.
UniGene	Mm.306548. Mm.3229.
3D structure databases
ProteinModelPortal	P61255.
ModBase	Search...
PTM databases
PhosphoSite	P61255.
Proteomic databases
PaxDb	P61255.
PRIDE	P61255.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000073471; ENSMUSP00000073175; ENSMUSG00000060938. ENSMUST00000167436; ENSMUSP00000129072; ENSMUSG00000060938.
GeneID	19941.
KEGG	mmu:19941.
Organism-specific databases
CTD	6154.
MGI	MGI:106022. Rpl26.
Phylogenomic databases
eggNOG	COG0198.
HOGENOM	HOG000216571.
HOVERGEN	HBG017293.
InParanoid	P61255.
KO	K02898.
OMA	VRIMRGD.
OrthoDB	EOG4TF0MM.
Gene expression databases
ArrayExpress	P61255.
Bgee	P61255.
CleanEx	MM_RPL26.
Genevestigator	P61255.
GermOnline	ENSMUSG00000060938. Mus musculus. ENSMUSG00000063754. Mus musculus.
Family and domain databases
Gene3D	2.30.30.30. 1 hit.
InterPro	IPR005824. KOW. IPR014722. Rib_L2_dom2. IPR005825. Ribosomal_L24/26_CS. IPR005756. Ribosomal_L26/L24P_euk/arc. IPR008991. Translation_prot_SH3-like. [Graphical view]
PANTHER	PTHR11143. PTHR11143. 1 hit.
Pfam	PF00467. KOW. 1 hit. [Graphical view]
SMART	SM00739. KOW. 1 hit. [Graphical view]
SUPFAM	SSF50104. Transl_SH3_like. 1 hit.
TIGRFAMs	TIGR01080. rplX_A_E. 1 hit.
PROSITE	PS01108. RIBOSOMAL_L24. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	23899.
SOURCE	Search...

Entry information

Entry name

RL26_MOUSE

Accession

Primary (citable) accession number: P61255
Secondary accession number(s): Q02877

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 10, 2004
Last sequence update:	May 10, 2004
Last modified:	May 1, 2013
This is version 74 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program