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P61108

- DEOC1_STAAM

UniProt

P61108 - DEOC1_STAAM

Protein

Deoxyribose-phosphate aldolase 1

Gene

deoC1

Organism
Staphylococcus aureus (strain Mu50 / ATCC 700699)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 80 (01 Oct 2014)
      Sequence version 1 (26 Apr 2004)
      Previous versions | rss
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    Functioni

    Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.By similarity

    Catalytic activityi

    2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei151 – 1511Schiff-base intermediate with acetaldehydeBy similarity
    Active sitei180 – 1801By similarity

    GO - Molecular functioni

    1. deoxyribose-phosphate aldolase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbohydrate catabolic process Source: UniProtKB-HAMAP
    2. deoxyribonucleotide catabolic process Source: InterPro
    3. deoxyribose phosphate catabolic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Lyase

    Keywords - Ligandi

    Schiff base

    Enzyme and pathway databases

    BioCyciSAUR158878:GJJ5-138-MONOMER.
    UniPathwayiUPA00002; UER00468.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Deoxyribose-phosphate aldolase 1 (EC:4.1.2.4)
    Short name:
    DERA 1
    Alternative name(s):
    2-deoxy-D-ribose 5-phosphate aldolase 1
    Phosphodeoxyriboaldolase 1
    Short name:
    Deoxyriboaldolase 1
    Gene namesi
    Name:deoC1
    Synonyms:dra
    Ordered Locus Names:SAV0138
    OrganismiStaphylococcus aureus (strain Mu50 / ATCC 700699)
    Taxonomic identifieri158878 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000002481: Chromosome

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 220220Deoxyribose-phosphate aldolase 1PRO_0000057257Add
    BLAST

    2D gel databases

    World-2DPAGE0002:P61108.

    Interactioni

    Protein-protein interaction databases

    STRINGi158878.SAV0138.

    Structurei

    3D structure databases

    ProteinModelPortaliP61108.
    SMRiP61108. Positions 5-214.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0274.
    HOGENOMiHOG000241645.
    KOiK01619.
    OMAiYVYEDIR.
    OrthoDBiEOG6QZMW5.
    PhylomeDBiP61108.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00114. DeoC_type1.
    InterProiIPR013785. Aldolase_TIM.
    IPR011343. DeoC.
    IPR002915. DeoC/FbaB/lacD_aldolase.
    IPR028581. DeoC_typeI.
    [Graphical view]
    PANTHERiPTHR10889. PTHR10889. 1 hit.
    PfamiPF01791. DeoC. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001357. DeoC. 1 hit.
    TIGRFAMsiTIGR00126. deoC. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P61108-1 [UniParc]FASTAAdd to Basket

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    MKFEKYIDHT LLKPESTRTQ IDQIIDEAKA YNFKSVCVNP THVKYAAERL    50
    ADSEVLVCTV IGFPLGASTT ATKAFETEDA IQNGADEIDM VINIGALKDG 100
    RFDDVQQDIE AVVKAAKGHT VKVIIETVLL DHDEIVKASE LTKAAGADFV 150
    KTSTGFAGGG ATAEDVKLMK DTVGADVEVK ASGGVRNLED FNKMVEAGAT 200
    RIGASAGVQI MQGLEADSDY 220
    Length:220
    Mass (Da):23,472
    Last modified:April 26, 2004 - v1
    Checksum:iA77DAC561C6B70A3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000017 Genomic DNA. Translation: BAB56300.1.
    RefSeqiNP_370662.1. NC_002758.2.

    Genome annotation databases

    EnsemblBacteriaiBAB56300; BAB56300; SAV0138.
    GeneIDi1120097.
    KEGGisav:SAV0138.
    PATRICi19560877. VBIStaAur52173_0136.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000017 Genomic DNA. Translation: BAB56300.1 .
    RefSeqi NP_370662.1. NC_002758.2.

    3D structure databases

    ProteinModelPortali P61108.
    SMRi P61108. Positions 5-214.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 158878.SAV0138.

    2D gel databases

    World-2DPAGE 0002:P61108.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAB56300 ; BAB56300 ; SAV0138 .
    GeneIDi 1120097.
    KEGGi sav:SAV0138.
    PATRICi 19560877. VBIStaAur52173_0136.

    Phylogenomic databases

    eggNOGi COG0274.
    HOGENOMi HOG000241645.
    KOi K01619.
    OMAi YVYEDIR.
    OrthoDBi EOG6QZMW5.
    PhylomeDBi P61108.

    Enzyme and pathway databases

    UniPathwayi UPA00002 ; UER00468 .
    BioCyci SAUR158878:GJJ5-138-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00114. DeoC_type1.
    InterProi IPR013785. Aldolase_TIM.
    IPR011343. DeoC.
    IPR002915. DeoC/FbaB/lacD_aldolase.
    IPR028581. DeoC_typeI.
    [Graphical view ]
    PANTHERi PTHR10889. PTHR10889. 1 hit.
    Pfami PF01791. DeoC. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001357. DeoC. 1 hit.
    TIGRFAMsi TIGR00126. deoC. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Mu50 / ATCC 700699.

    Entry informationi

    Entry nameiDEOC1_STAAM
    AccessioniPrimary (citable) accession number: P61108
    Secondary accession number(s): Q99X77
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 26, 2004
    Last sequence update: April 26, 2004
    Last modified: October 1, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3