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P61106

- RAB14_HUMAN

UniProt

P61106 - RAB14_HUMAN

Protein

Ras-related protein Rab-14

Gene

RAB14

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 125 (01 Oct 2014)
      Sequence version 4 (23 Jan 2007)
      Previous versions | rss
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    Functioni

    Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes By similarity. Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion.By similarity1 Publication

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi18 – 269GTP
    Nucleotide bindingi66 – 705GTP
    Nucleotide bindingi124 – 1274GTP
    Nucleotide bindingi154 – 1563GTP

    GO - Molecular functioni

    1. GDP binding Source: UniProtKB
    2. GTPase activity Source: UniProtKB
    3. GTP binding Source: UniProtKB
    4. protein binding Source: UniProtKB

    GO - Biological processi

    1. embryo development Source: UniProtKB
    2. endocytic recycling Source: UniProtKB
    3. fibroblast growth factor receptor signaling pathway Source: UniProtKB
    4. Golgi to endosome transport Source: UniProtKB
    5. GTP catabolic process Source: GOC
    6. intracellular transport Source: UniProtKB
    7. membrane organization Source: Reactome
    8. protein transport Source: UniProtKB-KW
    9. regulation of protein localization Source: UniProtKB
    10. small GTPase mediated signal transduction Source: InterPro
    11. vesicle-mediated transport Source: UniProtKB

    Keywords - Biological processi

    Protein transport, Transport

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    ReactomeiREACT_147867. Translocation of GLUT4 to the plasma membrane.
    SignaLinkiP61106.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ras-related protein Rab-14
    Gene namesi
    Name:RAB14
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 9

    Organism-specific databases

    HGNCiHGNC:16524. RAB14.

    Subcellular locationi

    Recycling endosome. Early endosome membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane By similarity; Lipid-anchor By similarity; Cytoplasmic side By similarity. Golgi apparatustrans-Golgi network membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesiclephagosome. Cytoplasmic vesiclephagosome membrane By similarity; Lipid-anchor By similarity; Cytoplasmic side By similarity
    Note: Recruited to recycling endosomes by DENND6A. Recruited to phagosomes containing S.aureus or M.tuberculosis.

    GO - Cellular componenti

    1. cytoplasmic vesicle membrane Source: Reactome
    2. cytosol Source: UniProtKB
    3. early endosome Source: UniProtKB
    4. early endosome membrane Source: UniProtKB-SubCell
    5. extracellular vesicular exosome Source: UniProt
    6. Golgi membrane Source: UniProtKB-SubCell
    7. Golgi stack Source: UniProtKB
    8. intracellular Source: LIFEdb
    9. intracellular membrane-bounded organelle Source: HPA
    10. late endosome Source: UniProtKB
    11. lysosomal membrane Source: UniProtKB
    12. lysosome Source: UniProtKB
    13. nuclear outer membrane-endoplasmic reticulum membrane network Source: UniProtKB
    14. perinuclear region of cytoplasm Source: UniProtKB
    15. phagocytic vesicle Source: UniProtKB
    16. phagocytic vesicle membrane Source: UniProtKB-SubCell
    17. plasma membrane Source: UniProtKB
    18. recycling endosome Source: UniProtKB
    19. rough endoplasmic reticulum Source: UniProtKB
    20. trans-Golgi network transport vesicle Source: UniProtKB

    Keywords - Cellular componenti

    Cytoplasmic vesicle, Endosome, Golgi apparatus, Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA34104.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed3 Publications
    Chaini2 – 215214Ras-related protein Rab-14PRO_0000121185Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei2 – 21N-acetylalanine3 Publications
    Lipidationi213 – 2131S-geranylgeranyl cysteineBy similarity
    Modified residuei215 – 2151Cysteine methyl esterBy similarity
    Lipidationi215 – 2151S-geranylgeranyl cysteineBy similarity

    Keywords - PTMi

    Acetylation, Lipoprotein, Methylation, Prenylation

    Proteomic databases

    MaxQBiP61106.
    PaxDbiP61106.
    PeptideAtlasiP61106.
    PRIDEiP61106.

    PTM databases

    PhosphoSiteiP61106.

    Expressioni

    Gene expression databases

    BgeeiP61106.
    CleanExiHS_RAB14.
    GenevestigatoriP61106.

    Organism-specific databases

    HPAiHPA026419.

    Interactioni

    Subunit structurei

    Interacts with KIF16B By similarity. Interacts with ZFYVE20.By similarity2 Publications

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    OCRLQ019683EBI-1056404,EBI-6148898

    Protein-protein interaction databases

    BioGridi119605. 25 interactions.
    DIPiDIP-42491N.
    IntActiP61106. 11 interactions.
    MINTiMINT-2882831.
    STRINGi9606.ENSP00000362946.

    Structurei

    Secondary structure

    1
    215
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi9 – 179
    Helixi24 – 3310
    Beta strandi48 – 558
    Beta strandi58 – 669
    Helixi70 – 723
    Helixi75 – 828
    Beta strandi85 – 928
    Helixi96 – 1005
    Helixi102 – 11211
    Beta strandi118 – 1247
    Helixi129 – 1313
    Helixi136 – 14510
    Beta strandi149 – 1524
    Turni155 – 1573
    Helixi161 – 17212

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1Z0FX-ray2.15A2-175[»]
    4DRZX-ray2.30A1-177[»]
    ProteinModelPortaliP61106.
    SMRiP61106. Positions 7-173.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP61106.

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi40 – 489Effector regionBy similarity

    Sequence similaritiesi

    Belongs to the small GTPase superfamily. Rab family.Curated

    Phylogenomic databases

    eggNOGiCOG1100.
    HOVERGENiHBG009351.
    InParanoidiP61106.
    KOiK07881.
    OMAiASCPHTI.
    OrthoDBiEOG7QK0CV.
    PhylomeDBiP61106.
    TreeFamiTF300032.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR001806. Small_GTPase.
    IPR003579. Small_GTPase_Rab_type.
    [Graphical view]
    PfamiPF00071. Ras. 1 hit.
    [Graphical view]
    PRINTSiPR00449. RASTRNSFRMNG.
    SMARTiSM00175. RAB. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00231. small_GTP. 1 hit.
    PROSITEiPS51419. RAB. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P61106-1 [UniParc]FASTAAdd to Basket

    « Hide

    MATAPYNYSY IFKYIIIGDM GVGKSCLLHQ FTEKKFMADC PHTIGVEFGT    50
    RIIEVSGQKI KLQIWDTAGQ ERFRAVTRSY YRGAAGALMV YDITRRSTYN 100
    HLSSWLTDAR NLTNPNTVII LIGNKADLEA QRDVTYEEAK QFAEENGLLF 150
    LEASAKTGEN VEDAFLEAAK KIYQNIQDGS LDLNAAESGV QHKPSAPQGG 200
    RLTSEPQPQR EGCGC 215
    Length:215
    Mass (Da):23,897
    Last modified:January 23, 2007 - v4
    Checksum:iBC8A8B98FB9944AC
    GO

    Sequence cautioni

    The sequence CAI12361.1 differs from that shown. Reason: Erroneous gene model prediction.

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti4 – 41A → T.3 Publications
    VAR_012986

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF152463 mRNA. Translation: AAF00150.1.
    AF203689 mRNA. Translation: AAF19400.1.
    AY553875 mRNA. Translation: AAS64573.1.
    AF112206 mRNA. Translation: AAF17194.1.
    AL162081 mRNA. Translation: CAB82414.1.
    AK023524 mRNA. Translation: BAB14598.1.
    AK090889 mRNA. Translation: BAG52243.1.
    AF498949 mRNA. Translation: AAM21097.1.
    AL137068 Genomic DNA. Translation: CAD20124.1.
    AL137068 Genomic DNA. Translation: CAI12361.1. Sequence problems.
    CR457394 mRNA. Translation: CAG33675.1.
    CH471090 Genomic DNA. Translation: EAW87487.1.
    BC006081 mRNA. Translation: AAH06081.1.
    CCDSiCCDS6827.1.
    RefSeqiNP_057406.2. NM_016322.3.
    UniGeneiHs.371563.

    Genome annotation databases

    EnsembliENST00000373840; ENSP00000362946; ENSG00000119396.
    GeneIDi51552.
    KEGGihsa:51552.
    UCSCiuc004blc.3. human.

    Polymorphism databases

    DMDMi85700392.

    Keywords - Coding sequence diversityi

    Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF152463 mRNA. Translation: AAF00150.1 .
    AF203689 mRNA. Translation: AAF19400.1 .
    AY553875 mRNA. Translation: AAS64573.1 .
    AF112206 mRNA. Translation: AAF17194.1 .
    AL162081 mRNA. Translation: CAB82414.1 .
    AK023524 mRNA. Translation: BAB14598.1 .
    AK090889 mRNA. Translation: BAG52243.1 .
    AF498949 mRNA. Translation: AAM21097.1 .
    AL137068 Genomic DNA. Translation: CAD20124.1 .
    AL137068 Genomic DNA. Translation: CAI12361.1 . Sequence problems.
    CR457394 mRNA. Translation: CAG33675.1 .
    CH471090 Genomic DNA. Translation: EAW87487.1 .
    BC006081 mRNA. Translation: AAH06081.1 .
    CCDSi CCDS6827.1.
    RefSeqi NP_057406.2. NM_016322.3.
    UniGenei Hs.371563.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1Z0F X-ray 2.15 A 2-175 [» ]
    4DRZ X-ray 2.30 A 1-177 [» ]
    ProteinModelPortali P61106.
    SMRi P61106. Positions 7-173.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 119605. 25 interactions.
    DIPi DIP-42491N.
    IntActi P61106. 11 interactions.
    MINTi MINT-2882831.
    STRINGi 9606.ENSP00000362946.

    PTM databases

    PhosphoSitei P61106.

    Polymorphism databases

    DMDMi 85700392.

    Proteomic databases

    MaxQBi P61106.
    PaxDbi P61106.
    PeptideAtlasi P61106.
    PRIDEi P61106.

    Protocols and materials databases

    DNASUi 51552.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000373840 ; ENSP00000362946 ; ENSG00000119396 .
    GeneIDi 51552.
    KEGGi hsa:51552.
    UCSCi uc004blc.3. human.

    Organism-specific databases

    CTDi 51552.
    GeneCardsi GC09M123940.
    HGNCi HGNC:16524. RAB14.
    HPAi HPA026419.
    MIMi 612673. gene.
    neXtProti NX_P61106.
    PharmGKBi PA34104.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG1100.
    HOVERGENi HBG009351.
    InParanoidi P61106.
    KOi K07881.
    OMAi ASCPHTI.
    OrthoDBi EOG7QK0CV.
    PhylomeDBi P61106.
    TreeFami TF300032.

    Enzyme and pathway databases

    Reactomei REACT_147867. Translocation of GLUT4 to the plasma membrane.
    SignaLinki P61106.

    Miscellaneous databases

    ChiTaRSi RAB14. human.
    EvolutionaryTracei P61106.
    GeneWikii RAB14.
    GenomeRNAii 51552.
    NextBioi 55334.
    PROi P61106.
    SOURCEi Search...

    Gene expression databases

    Bgeei P61106.
    CleanExi HS_RAB14.
    Genevestigatori P61106.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR001806. Small_GTPase.
    IPR003579. Small_GTPase_Rab_type.
    [Graphical view ]
    Pfami PF00071. Ras. 1 hit.
    [Graphical view ]
    PRINTSi PR00449. RASTRNSFRMNG.
    SMARTi SM00175. RAB. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00231. small_GTP. 1 hit.
    PROSITEi PS51419. RAB. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Human Rab14 cloning and intracellular localization to the biosynthetic/secretory trafficking pathway."
      Proikas-Cezanne T., Jenkins J.R.
      Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], VARIANT THR-4.
      Tissue: Liver.
    2. "Cloning and characterization of human small GTPase Rab14."
      Ren Y.
      Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], VARIANT THR-4.
    3. "Screening and identification of HCV F protein-binding protein 1."
      Huang Y.-P., Wang L., Cheng J.
      Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Adrenal gland.
    5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Melanoma.
    6. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Amygdala and Placenta.
    7. "cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)."
      Puhl H.L. III, Ikeda S.R., Aronstam R.S.
      Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT THR-4.
      Tissue: Brain.
    8. "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
      Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    9. "DNA sequence and analysis of human chromosome 9."
      Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
      , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
      Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    10. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    11. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Placenta.
    12. Bienvenut W.V., Claeys D.
      Submitted (FEB-2006) to UniProtKB
      Cited for: PROTEIN SEQUENCE OF 2-24; 36-59; 62-72; 83-95; 97-132 AND 141-171, CLEAVAGE OF INITIATOR METHIONINE, ACETYLATION AT ALA-2, IDENTIFICATION BY MASS SPECTROMETRY.
      Tissue: B-cell lymphoma and Platelet.
    13. "Rab14 is part of the early endosomal clathrin-coated TGN microdomain."
      Proikas-Cezanne T., Gaugel A., Frickey T., Nordheim A.
      FEBS Lett. 580:5241-5246(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION.
    14. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
      Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    15. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    16. "Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes."
      Seto S., Tsujimura K., Koide Y.
      Traffic 12:407-420(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION.
    17. "Rab14 and its exchange factor FAM116 link endocytic recycling and adherens junction stability in migrating cells."
      Linford A., Yoshimura S., Nunes Bastos R., Langemeyer L., Gerondopoulos A., Rigden D.J., Barr F.A.
      Dev. Cell 22:952-966(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, SUBCELLULAR LOCATION.
    18. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
      Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T., Giglione C.
      Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    19. "Structural basis of family-wide Rab GTPase recognition by rabenosyn-5."
      Eathiraj S., Pan X., Ritacco C., Lambright D.G.
      Nature 436:415-419(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.15 ANGSTROMS) OF 2-175 IN COMPLEX WITH GDP, INTERACTION WITH ZFYVE20.
    20. "Crystal structure of human RAB14."
      Structural genomics consortium (SGC)
      Submitted (FEB-2009) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 1-181 IN COMPLEX WITH GDP.

    Entry informationi

    Entry nameiRAB14_HUMAN
    AccessioniPrimary (citable) accession number: P61106
    Secondary accession number(s): B3KR31
    , P35287, Q5JVD4, Q6Q7K5, Q969L0, Q9UI11
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 26, 2004
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 125 of the entry and version 4 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. Human chromosome 9
      Human chromosome 9: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    6. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3