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P61106

- RAB14_HUMAN

UniProt

P61106 - RAB14_HUMAN

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Protein
Ras-related protein Rab-14
Gene
RAB14
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes By similarity. Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion.1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi18 – 269GTP
Nucleotide bindingi66 – 705GTP
Nucleotide bindingi124 – 1274GTP
Nucleotide bindingi154 – 1563GTP

GO - Molecular functioni

  1. GDP binding Source: UniProtKB
  2. GTP binding Source: UniProtKB
  3. GTPase activity Source: UniProtKB
  4. protein binding Source: UniProtKB
Complete GO annotation...

GO - Biological processi

  1. GTP catabolic process Source: GOC
  2. Golgi to endosome transport Source: UniProtKB
  3. embryo development Source: UniProtKB
  4. endocytic recycling Source: UniProtKB
  5. fibroblast growth factor receptor signaling pathway Source: UniProtKB
  6. intracellular transport Source: UniProtKB
  7. membrane organization Source: Reactome
  8. protein transport Source: UniProtKB-KW
  9. regulation of protein localization Source: UniProtKB
  10. small GTPase mediated signal transduction Source: InterPro
  11. vesicle-mediated transport Source: UniProtKB
Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiREACT_147867. Translocation of GLUT4 to the plasma membrane.
SignaLinkiP61106.

Names & Taxonomyi

Protein namesi
Recommended name:
Ras-related protein Rab-14
Gene namesi
Name:RAB14
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 9

Organism-specific databases

HGNCiHGNC:16524. RAB14.

Subcellular locationi

Recycling endosome. Early endosome membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side By similarity. Golgi apparatustrans-Golgi network membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesiclephagosome. Cytoplasmic vesiclephagosome membrane; Lipid-anchor; Cytoplasmic side By similarity
Note: Recruited to recycling endosomes by DENND6A. Recruited to phagosomes containing S.aureus or M.tuberculosis.3 Publications

GO - Cellular componenti

  1. Golgi membrane Source: UniProtKB-SubCell
  2. Golgi stack Source: UniProtKB
  3. cytoplasmic vesicle membrane Source: Reactome
  4. cytosol Source: UniProtKB
  5. early endosome Source: UniProtKB
  6. early endosome membrane Source: UniProtKB-SubCell
  7. extracellular vesicular exosome Source: UniProt
  8. intracellular Source: LIFEdb
  9. intracellular membrane-bounded organelle Source: HPA
  10. late endosome Source: UniProtKB
  11. lysosomal membrane Source: UniProtKB
  12. lysosome Source: UniProtKB
  13. nuclear outer membrane-endoplasmic reticulum membrane network Source: UniProtKB
  14. perinuclear region of cytoplasm Source: UniProtKB
  15. phagocytic vesicle Source: UniProtKB
  16. phagocytic vesicle membrane Source: UniProtKB-SubCell
  17. plasma membrane Source: UniProtKB
  18. recycling endosome Source: UniProtKB
  19. rough endoplasmic reticulum Source: UniProtKB
  20. trans-Golgi network transport vesicle Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasmic vesicle, Endosome, Golgi apparatus, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA34104.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed1 Publication
Chaini2 – 215214Ras-related protein Rab-14
PRO_0000121185Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanine3 Publications
Lipidationi213 – 2131S-geranylgeranyl cysteine By similarity
Modified residuei215 – 2151Cysteine methyl ester By similarity
Lipidationi215 – 2151S-geranylgeranyl cysteine By similarity

Keywords - PTMi

Acetylation, Lipoprotein, Methylation, Prenylation

Proteomic databases

MaxQBiP61106.
PaxDbiP61106.
PeptideAtlasiP61106.
PRIDEiP61106.

PTM databases

PhosphoSiteiP61106.

Expressioni

Gene expression databases

BgeeiP61106.
CleanExiHS_RAB14.
GenevestigatoriP61106.

Organism-specific databases

HPAiHPA026419.

Interactioni

Subunit structurei

Interacts with KIF16B By similarity. Interacts with ZFYVE20.1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
OCRLQ019683EBI-1056404,EBI-6148898

Protein-protein interaction databases

BioGridi119605. 25 interactions.
DIPiDIP-42491N.
IntActiP61106. 11 interactions.
MINTiMINT-2882831.
STRINGi9606.ENSP00000362946.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi9 – 179
Helixi24 – 3310
Beta strandi48 – 558
Beta strandi58 – 669
Helixi70 – 723
Helixi75 – 828
Beta strandi85 – 928
Helixi96 – 1005
Helixi102 – 11211
Beta strandi118 – 1247
Helixi129 – 1313
Helixi136 – 14510
Beta strandi149 – 1524
Turni155 – 1573
Helixi161 – 17212

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1Z0FX-ray2.15A2-175[»]
4DRZX-ray2.30A1-177[»]
ProteinModelPortaliP61106.
SMRiP61106. Positions 7-173.

Miscellaneous databases

EvolutionaryTraceiP61106.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi40 – 489Effector region By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1100.
HOVERGENiHBG009351.
InParanoidiP61106.
KOiK07881.
OMAiASCPHTI.
OrthoDBiEOG7QK0CV.
PhylomeDBiP61106.
TreeFamiTF300032.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
IPR003579. Small_GTPase_Rab_type.
[Graphical view]
PfamiPF00071. Ras. 1 hit.
[Graphical view]
PRINTSiPR00449. RASTRNSFRMNG.
SMARTiSM00175. RAB. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51419. RAB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P61106-1 [UniParc]FASTAAdd to Basket

« Hide

MATAPYNYSY IFKYIIIGDM GVGKSCLLHQ FTEKKFMADC PHTIGVEFGT    50
RIIEVSGQKI KLQIWDTAGQ ERFRAVTRSY YRGAAGALMV YDITRRSTYN 100
HLSSWLTDAR NLTNPNTVII LIGNKADLEA QRDVTYEEAK QFAEENGLLF 150
LEASAKTGEN VEDAFLEAAK KIYQNIQDGS LDLNAAESGV QHKPSAPQGG 200
RLTSEPQPQR EGCGC 215
Length:215
Mass (Da):23,897
Last modified:January 23, 2007 - v4
Checksum:iBC8A8B98FB9944AC
GO

Sequence cautioni

The sequence CAI12361.1 differs from that shown. Reason: Erroneous gene model prediction.

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti4 – 41A → T.3 Publications
VAR_012986

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF152463 mRNA. Translation: AAF00150.1.
AF203689 mRNA. Translation: AAF19400.1.
AY553875 mRNA. Translation: AAS64573.1.
AF112206 mRNA. Translation: AAF17194.1.
AL162081 mRNA. Translation: CAB82414.1.
AK023524 mRNA. Translation: BAB14598.1.
AK090889 mRNA. Translation: BAG52243.1.
AF498949 mRNA. Translation: AAM21097.1.
AL137068 Genomic DNA. Translation: CAD20124.1.
AL137068 Genomic DNA. Translation: CAI12361.1. Sequence problems.
CR457394 mRNA. Translation: CAG33675.1.
CH471090 Genomic DNA. Translation: EAW87487.1.
BC006081 mRNA. Translation: AAH06081.1.
CCDSiCCDS6827.1.
RefSeqiNP_057406.2. NM_016322.3.
UniGeneiHs.371563.

Genome annotation databases

EnsembliENST00000373840; ENSP00000362946; ENSG00000119396.
GeneIDi51552.
KEGGihsa:51552.
UCSCiuc004blc.3. human.

Polymorphism databases

DMDMi85700392.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF152463 mRNA. Translation: AAF00150.1 .
AF203689 mRNA. Translation: AAF19400.1 .
AY553875 mRNA. Translation: AAS64573.1 .
AF112206 mRNA. Translation: AAF17194.1 .
AL162081 mRNA. Translation: CAB82414.1 .
AK023524 mRNA. Translation: BAB14598.1 .
AK090889 mRNA. Translation: BAG52243.1 .
AF498949 mRNA. Translation: AAM21097.1 .
AL137068 Genomic DNA. Translation: CAD20124.1 .
AL137068 Genomic DNA. Translation: CAI12361.1 . Sequence problems.
CR457394 mRNA. Translation: CAG33675.1 .
CH471090 Genomic DNA. Translation: EAW87487.1 .
BC006081 mRNA. Translation: AAH06081.1 .
CCDSi CCDS6827.1.
RefSeqi NP_057406.2. NM_016322.3.
UniGenei Hs.371563.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1Z0F X-ray 2.15 A 2-175 [» ]
4DRZ X-ray 2.30 A 1-177 [» ]
ProteinModelPortali P61106.
SMRi P61106. Positions 7-173.
ModBasei Search...

Protein-protein interaction databases

BioGridi 119605. 25 interactions.
DIPi DIP-42491N.
IntActi P61106. 11 interactions.
MINTi MINT-2882831.
STRINGi 9606.ENSP00000362946.

PTM databases

PhosphoSitei P61106.

Polymorphism databases

DMDMi 85700392.

Proteomic databases

MaxQBi P61106.
PaxDbi P61106.
PeptideAtlasi P61106.
PRIDEi P61106.

Protocols and materials databases

DNASUi 51552.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000373840 ; ENSP00000362946 ; ENSG00000119396 .
GeneIDi 51552.
KEGGi hsa:51552.
UCSCi uc004blc.3. human.

Organism-specific databases

CTDi 51552.
GeneCardsi GC09M123940.
HGNCi HGNC:16524. RAB14.
HPAi HPA026419.
MIMi 612673. gene.
neXtProti NX_P61106.
PharmGKBi PA34104.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG1100.
HOVERGENi HBG009351.
InParanoidi P61106.
KOi K07881.
OMAi ASCPHTI.
OrthoDBi EOG7QK0CV.
PhylomeDBi P61106.
TreeFami TF300032.

Enzyme and pathway databases

Reactomei REACT_147867. Translocation of GLUT4 to the plasma membrane.
SignaLinki P61106.

Miscellaneous databases

ChiTaRSi RAB14. human.
EvolutionaryTracei P61106.
GeneWikii RAB14.
GenomeRNAii 51552.
NextBioi 55334.
PROi P61106.
SOURCEi Search...

Gene expression databases

Bgeei P61106.
CleanExi HS_RAB14.
Genevestigatori P61106.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
InterProi IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
IPR003579. Small_GTPase_Rab_type.
[Graphical view ]
Pfami PF00071. Ras. 1 hit.
[Graphical view ]
PRINTSi PR00449. RASTRNSFRMNG.
SMARTi SM00175. RAB. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00231. small_GTP. 1 hit.
PROSITEi PS51419. RAB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Human Rab14 cloning and intracellular localization to the biosynthetic/secretory trafficking pathway."
    Proikas-Cezanne T., Jenkins J.R.
    Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], VARIANT THR-4.
    Tissue: Liver.
  2. "Cloning and characterization of human small GTPase Rab14."
    Ren Y.
    Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], VARIANT THR-4.
  3. "Screening and identification of HCV F protein-binding protein 1."
    Huang Y.-P., Wang L., Cheng J.
    Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Adrenal gland.
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Melanoma.
  6. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Amygdala and Placenta.
  7. "cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)."
    Puhl H.L. III, Ikeda S.R., Aronstam R.S.
    Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT THR-4.
    Tissue: Brain.
  8. "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
    Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
    Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  9. "DNA sequence and analysis of human chromosome 9."
    Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
    , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
    Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  10. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  11. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Placenta.
  12. Bienvenut W.V., Claeys D.
    Submitted (FEB-2006) to UniProtKB
    Cited for: PROTEIN SEQUENCE OF 2-24; 36-59; 62-72; 83-95; 97-132 AND 141-171, CLEAVAGE OF INITIATOR METHIONINE, ACETYLATION AT ALA-2, IDENTIFICATION BY MASS SPECTROMETRY.
    Tissue: B-cell lymphoma and Platelet.
  13. "Rab14 is part of the early endosomal clathrin-coated TGN microdomain."
    Proikas-Cezanne T., Gaugel A., Frickey T., Nordheim A.
    FEBS Lett. 580:5241-5246(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION.
  14. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  15. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  16. "Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes."
    Seto S., Tsujimura K., Koide Y.
    Traffic 12:407-420(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION.
  17. "Rab14 and its exchange factor FAM116 link endocytic recycling and adherens junction stability in migrating cells."
    Linford A., Yoshimura S., Nunes Bastos R., Langemeyer L., Gerondopoulos A., Rigden D.J., Barr F.A.
    Dev. Cell 22:952-966(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION.
  18. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
    Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T., Giglione C.
    Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  19. "Structural basis of family-wide Rab GTPase recognition by rabenosyn-5."
    Eathiraj S., Pan X., Ritacco C., Lambright D.G.
    Nature 436:415-419(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.15 ANGSTROMS) OF 2-175 IN COMPLEX WITH GDP, INTERACTION WITH ZFYVE20.
  20. "Crystal structure of human RAB14."
    Structural genomics consortium (SGC)
    Submitted (FEB-2009) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 1-181 IN COMPLEX WITH GDP.

Entry informationi

Entry nameiRAB14_HUMAN
AccessioniPrimary (citable) accession number: P61106
Secondary accession number(s): B3KR31
, P35287, Q5JVD4, Q6Q7K5, Q969L0, Q9UI11
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: January 23, 2007
Last modified: September 3, 2014
This is version 124 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi